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    League City, TX
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    League City, TX Office Spaces for Lease

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    Dickinson, TX Webster, TX Houston, TX
    13 results
    South Shore
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    High-Visibility Retail and Flex Space
    $24 SF/Yr
    10,000 SF
    High-Visibility Retail and Flex Space

    2403 Gulf Freeway S, League City, TX

    Newly built 10,000 SF retail/flex space with freeway visibility.
    • Prime I‑45 visibility in a high‑traffic location near major retailers.
    • Strategic future access to SH 99 with designated access point less than a mile away.
    • Newly built 10,000 SF high‑impact retail and flex space suitable for office, retail, or medical use; can be subdivided.
    • Convenient access to major thoroughfares within a 10‑mile radius.
    • Proximity to Houston's Downtown and the #1 Medical Center in the World (25 miles).
    Updated: Jul 31, 2025
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    Professional/Medical Office Space Available
    $20 SF/Yr
    Professional/Medical Office Space Available

    1455 FM 646 West, League City, TX 77573

    Two-story office building near Gulf Freeway and UTMB Health.
    • Prime Location: Less than 1 mile east of the Gulf Freeway.
    • Proximity to Amenities: Close to shopping centers, UTMB Health League City campus, restaurants, retailers, and recreational facilities.
    • Well‑Maintained Building: Indicates a property in good condition.
    • Professional/Medical Office Building: Suited for specific business types.
    • Established Tenants: Includes All Care Medical Group, Texas Farm Bureau, Leigh Cates Law Firm, and League City Endodontics.
    Updated: Mar 5
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    Office/Retail Space on High-Traffic Road
    $24 SF/Yr
    Office/Retail Space on High-Traffic Road

    Versatile space suitable for office or retail use.

    549 Egret Bay Boulevard, League City, TX 77573

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    Medical Office Space For Rent
    $15 SF/Yr
    Medical Office Space For Rent

    Professional Center at South Shore Harbour, League City, TX

    3023 Marina Bay Dr -Ste 205, League City, TX 77573

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    Medical Office Complex For Rent
    Contact for pricing
    26,850 SF
    Medical Office Complex For Rent

    Three-building medical office complex near South Shore Harbour Resort.

    League City, TX 77573

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    Office Space for Lease
    Contact for pricing
    5,000 SF
    Office Space for Lease

    Flexible office suites are available for lease, ranging from 1,000 to 5,000 square feet.

    951 FM 646 Rd, League City, TX 77573

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    Professional/Medical Office Space Available
    $20 SF/Yr
    800 SF
    Professional/Medical Office Space Available

    Well-maintained office building near Gulf Freeway and UTMB Health.

    1455 FM 646, League City, TX

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    League City Commercial Suites Available
    $19 SF/Yr
    3,300 SF
    League City Commercial Suites Available

    Two suites available: dental office and open space.

    1001 FM270, League City, TX 77573

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    Prime Medical and Retail Space
    $30 SF/Yr
    Prime Medical and Retail Space

    Medical and retail spaces available in League City, Texas.

    1320 W League City Pkwy, League City, TX 77573

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    Office Space in League City
    $15 SF/Yr
    1,453 SF
    Office Space in League City

    Office space available for lease in League City, TX.

    3023 Marina Bay Dr, League City, TX

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    Retail/Office Space For Lease
    $24 SF/Yr
    5,000 SF
    Retail/Office Space For Lease

    5,000 SF divisible space available for lease.

    3881 E League City Pkwy, League City, TX 77573

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    League City Flex Space Available
    Contact for pricing
    League City Flex Space Available

    Office, warehouse, and showroom space for lease in League City.

    4807 FM 646, League City, TX 77573

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    Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 13 Active listings in League City, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    New Retail Center in League
    $1.10 SF/Yr
    New Retail Center in League

    Centrally located retail center with move-in ready spaces.

    395 Columbia Memorial Parkway, Kemah, TX 77565

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    Professional Office Space Available
    $25 SF/Yr
    346 SF
    Professional Office Space Available

    Quality, affordable office space in Clear Lake area.

    1120 NASA Parkway, Houston, TX 77058

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    Well-Maintained Flex Space Available
    $16 SF/Yr
    6,000 SF
    Well-Maintained Flex Space Available

    Flex spaces available in thriving small-business community.

    351 Columbia Memorial Pkwy, Kemah, TX 77565

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    Professional Office Space Available
    $24 SF/Yr
    Professional Office Space Available

    Quality, affordable office space in a convenient Clear Lake location.

    1120 E NASA Pkwy, Houston, TX 77058

    View details

    Similar Spaces for Sale in League City, TX

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    League City Retail Center
    $2,913,000
    7,980 SF
    League City Retail Center

    7,980 SF shopping center with diverse tenants.

    2750 W Main St, League City, TX 77573

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    League City Industrial Facility For Sale
    $4,990,000
    29,244 SF
    League City Industrial Facility For Sale

    Industrial facility in a growing area between Houston and Galveston.

    2705 Dickinson Avenue, League City, TX 77573

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    League City Commercial Opportunity
    $2,600,000
    2,400 SF
    League City Commercial Opportunity

    Multiple properties for sale on high-traffic West Main Street.

    624 West Main Street, League City, TX 77573

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    League City Commercial Opportunity
    $2,600,000
    1.44 Acres
    League City Commercial Opportunity

    Prime commercial properties for sale in high-growth League City.

    610-620 W Main Street, League City, TX

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    Value-Add Office Building Opportunity
    Contact for pricing
    57,939 SF
    Value-Add Office Building Opportunity

    Class B office building with value-add potential in Clear Lake.

    3027 Marina Bay Dr, League City, TX 77573

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    League City Commercial Property
    $2,818,000
    6,688 SF
    League City Commercial Property

    Commercial property in League City, Texas, available for sale.

    3052 South Shore Blvd, League City, TX 77573

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    Commercial Land with High Visibility
    Contact for pricing
    Commercial Land with High Visibility

    Two-acre commercial land with frontage on two streets.

    1425 East Main Street, League City, TX 77573

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    League City Office Space Available
    $1,500,000
    1,400 SF
    League City Office Space Available

    Single-story office space with individual entry in League City, TX.

    820 Lawrence Road, League City, TX

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    League City Commercial Development Opportunity
    $6,000,000
    4.69 Acres
    League City Commercial Development Opportunity

    4.69-acre commercial property near Kemah Boardwalk, ready for development.

    820 Lawrence Rd, League City, TX 77573

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    Prime Commercial Tract on FM 270
    $730,414
    1.68 Acres
    Prime Commercial Tract on FM 270

    1.6768 acre tract ideal for retail, office, restaurant.

    0 S FM 270, League City, TX 77573

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cleared Commercial Lot For Lease
    Contact for pricing
    Cleared Commercial Lot For Lease

    1.33-acre commercial lot in growing New Braunfels market.

    943 King Arthur, New Braunfels, TX 78130

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    Prime Pad Site Near Baylor
    $105,000 SF/Yr
    30,797 SF
    Prime Pad Site Near Baylor

    30,798 SF lot near Baylor and Magnolia Silos.

    722 S 7th Street, Waco, TX 76706

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    Build-to-Suit Office Land Parcel
    $20,000/Mo
    20,000 SF
    Build-to-Suit Office Land Parcel

    Land offering build-to-suit development flexibility for an office complex in South Tyler near major roadways.

    5637 Paluxy Dr, Tyler, TX 75703

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    Build-to-Suit Retail/Office
    $3,480/Mo
    Build-to-Suit Retail/Office

    Flexible retail or office build-to-suit with C-1 zoning, NNN terms, and delivery planned for Summer 2027.

    5647 KPE Way, Tyler, TX 75703

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    League City, TX Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in League City, TX with 13 listings featured on our commercial real estate exchange. The current inventory includes 21,856 square feet of properties with an estimated lease value of $242 SF/Yr.

    Estimated lease rates for Office Spaces in League City, TX begin at $15 SF/Yr, with an average of $40 SF/Yr and extend to $140 SF/Yr.
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