League City, TX Medical Office Space for Rent & Lease

Updated: Jul 24

New Medical Professional Center

1070 FM 646 Road East, League City, TX 77573

$24 SF/Yr

Newly constructed medical and professional center built to serve imaging and physical therapy needs
Available spaces designed as an imaging center and physical therapy clinic
Capable of accommodating a variety of medical office and retail uses
Located on one of the area’s heavily traveled roadways
Easy access to Gulf Freeway (Interstate 45) and Highway 3

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Updated: Mar 5

Professional/Medical Office Space Available

1455 FM 646 West, League City, TX 77573

$20 SF/Yr

Prime Location: Less than 1 mile east of the Gulf Freeway.
Proximity to Amenities: Close to shopping centers, UTMB Health League City campus, restaurants, retailers, and recreational facilities.
Well‑Maintained Building: Indicates a property in good condition.
Professional/Medical Office Building: Suited for specific business types.
Established Tenants: Includes All Care Medical Group, Texas Farm Bureau, Leigh Cates Law Firm, and League City Endodontics.

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Medical Office Space For Rent

3023 Marina Bay Dr -Ste 205, League City, TX 77573

$15 SF/Yr

Professional Center at South Shore Harbour, League City, TX

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Prime Medical and Retail Space

1320 West League City Parkway, League City, TX 77573

$30 SF/Yr

Medical and retail spaces available in League City, Texas.

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League City Commercial Suites Available

1001 FM270, League City, TX 77573

Contact for pricing

3,300 sqft

Two suites available: dental office and open space.

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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 5 Active listings in League City, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Clinic Space

985 Nasa Rd 1, Webster, TX 77598

Contact for pricing

1,056 sqft

Clinic-oriented lease space with I-45 access and proximity to NASA Johnson Space Center and Clear Lake Regional Medical Center.

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Medical Office Building Near Freeway

1045 Gemini Street, Houston, TX 77058

Contact for pricing

40,214 sqft

Two-story medical office building with easy freeway access.

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Medical Office Building with Signage

202 N Texas Ave, Webster, TX 77598

Contact for pricing

Professional medical office space within the Clear Lake Medical Center, with monument and fascia signage available.

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Medical Office Building Near I-45

16840 Buccaneer Ln, Houston, TX 77058

Contact for pricing

40,038 sqft

Two-story medical office building with easy access to I-45.

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Similar Spaces for Sale in League City, TX

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Medical Office Building With MRI

2401 W FM 646, League City, TX 77573

Contact for pricing

13,200 sqft 1.46 AC lot

Fully occupied medical office property with diagnostic imaging infrastructure and immediate connectivity to Interstate 45.

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League City, TX Medical Office Space Lease Rates & Market Statistics

Browse 5 Medical Office Space listings for lease in League City, TX on Realmo, a commercial real estate marketplace serving the League City area. The current inventory totals 3,300 square feet of properties.

Asking lease rates for Medical Office Space in League City start at $15 SF/Yr, average $22.25 SF/Yr, and reach $30 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $22.25 SF/Yr, the local average runs 9% below Texas's state average of $24.57 SF/Yr.

League City accounts for 50% of the 10 medical office space listings currently available across Galveston County, where nearby markets include Texas City and Friendswood. Medical Office Space listings make up 38% of the 13 Office Spaces currently for lease in League City, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office Units (5 listings) and Office buildings (3 listings) elsewhere in the League City market.