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    South Setauket, NY
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    South Setauket, NY Office Spaces for Lease

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    East Setauket, NY Stonybrook, NY Lake Grove, NY
    7 listings
    Centereach Office Space For Rent
    $4,200/Mo
    2,500 SF
    Centereach Office Space For Rent

    2450 Middle Country Road, Centereach, NY 11720

    Highly visible Centereach office space with flexible layout options.
    • Second‑floor office suite with approximately 2,500 SF of flexible workspace on highly visible Middle Country Road in Centereach
    • Includes 6 private offices, including an executive office with a private bathroom, plus reception and open workstation area
    • Large conference room for meetings and client sessions
    • 3 bathrooms total, including 1 ADA‑accessible restroom
    • Stair lifts installed for accessibility; utilities and common charges paid by the tenant
    Updated: May 26
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    Built-Out Medical Office Suite
    $25 SF/Yr
    2,000 SF
    Built-Out Medical Office Suite

    1787 Middle Country Road, Centereach, NY 11720

    Move-in ready medical office with reception, waiting, five exam rooms, private office, and ample front and rear parking.
    • 2,000 SF medical office space available for lease
    • Built‑out interior includes large reception area and large waiting room
    • Features 5 private exam rooms plus a private office
    • Includes staff lounge, 3 bathrooms, and multiple storage closets
    • Ample front and rear parking
    Updated: Dec 11, 2025
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    Retail/Office Space For Rent
    $2,200/Mo
    Retail/Office Space For Rent

    Retail or office space available for rent.

    2570 Middle Country Rd, Centereach, NY 11720

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    Centereach Office Space Available
    $4,200/Mo
    2,500 SF
    Centereach Office Space Available

    Furnished Centereach office space with private offices and conference room.

    2450 Middle Country Rd, Centereach, NY 11720

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    Centereach Commercial Space For Lease
    Contact for pricing
    Centereach Commercial Space For Lease

    Commercial space available for lease in Centereach, New York.

    2101 Middle Country Rd, Centereach, NY 11720

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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 7 Active listings in South Setauket, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Lake Grove Office Space Available
    Contact for pricing
    4,500 SF
    Lake Grove Office Space Available

    Ground floor office space for lease on Middle Country Road.

    2780 Middle Country Rd, Lake Grove, NY

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    Lake Grove Office Space Available
    Contact for pricing
    Lake Grove Office Space Available

    Office space for lease in Lake Grove, New York.

    3070 Middle Country Rd, Lake Grove, NY 11755

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    Medical/Office Space For Lease
    $360/Mo
    Medical/Office Space For Lease

    Medical/Office space available for lease.

    500 Portion Rd, Lake Ronkonkoma, NY 11779

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    Lake Ronkonkoma Retail Center
    $17 SF/Yr
    87,560 SF
    Lake Ronkonkoma Retail Center

    Retail and office spaces available in Lake Ronkonkoma.

    601 Portion Rd, Lake Ronkonkoma, NY 11779

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    Similar Spaces for Sale in South Setauket, NY

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Centereach Office Space For Sale
    $699,000
    0.30 Acres
    Centereach Office Space For Sale

    Office spaces in high-traffic Centereach location on Middle Country Road.

    2539 Middle Country Road, Centereach, NY 11720

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    Established Dental Office For Sale
    Contact for pricing
    3,549 SF
    Established Dental Office For Sale

    Long-term dental tenant in medical corridor.

    1 Mark Tree Road, Centereach, NY 11720

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    Centereach Retail and Office Space
    Contact for pricing
    5,600 SF
    Centereach Retail and Office Space

    5,600 SqFt retail and office space available for sale.

    2101 Middle Country Rd, Centereach, NY 11720

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Corner Lot on Busy Road
    $1,500/Mo
    Corner Lot on Busy Road

    High-visibility commercial land for lease on a busy road.

    574 Montauk Highway, Shirley, NY 11967

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    Commercial Land in High-Traffic Area
    $1,000/Mo
    Commercial Land in High-Traffic Area

    0.18 acre vacant lot with high visibility and traffic.

    586 Montauk Highway, Shirley, NY 11967

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    Prime Land for Ground Lease
    Contact for pricing
    Prime Land for Ground Lease

    20,245 sq ft land in high-traffic retail corridor.

    550 William Floyd Parkway, Brookhaven, NY 11967

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    Prime Retail Corridor Land Lease
    $10,000/Mo
    Prime Retail Corridor Land Lease

    20,245 sq ft land for lease in Shirley, NY.

    550 William Floyd Pkwy, Shirley, NY 11967

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    South Setauket, NY Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in South Setauket, NY with 7 listings featured on our commercial real estate exchange. The current inventory includes 7,000 square feet of properties with an estimated lease value of $65 SF/Yr.

    Estimated lease rates for Office Spaces in South Setauket, NY begin at $20 SF/Yr, with an average of $21 SF/Yr and extend to $25 SF/Yr.
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