Desoto County, MS Medical Office Space for Rent & Lease

Updated: Nov 22, 2025

Medical Office Park Near I-55

7900 Airways Boulevard, Southaven, MS 38671

$19 SF/Yr

1,206 sqft $1,959/Mo

Conveniently located less than one mile from I‑55
3 Building Medical Office Park
Near Baptist DeSoto Hospital

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Updated: May 10, 2024

Office Space on Goodman Road

892 Goodman Rd E, Southaven, MS

$28 SF/Yr

1,500 sqft $3,600/Mo

Great location on Goodman Rd
Across the street from Southaven Commons Shopping Center
Suite 4 is a medical clinic buildout
Utilities included
Shared break area

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Hernando Medical Office Space

124 W Commerce St, Hernando, MS

$20 SF/Yr

4,608 sqft $7,872/Mo

Medical office space in the heart of Hernando.

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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 3 Active listings in Desoto County, MS, we suggest exploring alternatives. Similar 3 Properties for Sales.

Similar Spaces for Sale in Desoto County, MS

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Medical Office Building

4033 Fountain Lane, Horn Lake, MS 38637

$3,545,451

For sale medical office building well-suited for healthcare practices and related professional services.

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Southaven Medical Office Building

7732 Airways Blvd, Southaven, MS

$775,000

3,152 sqft 0.73 AC lot

3,152 SF building ideal for office or medical use.

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Professional Office Building For Sale

7289 Goodman Rd, Olive Branch, MS 38654

Contact for pricing

Two-story office building ideal for medical, professional, or service users.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Office Development Land For Lease

1323 Strawfloor Drive, Jonesboro, AR 72401

Contact for pricing

4,000 sqft

2.43 acres for office development with build-to-suit opportunity.

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Corner Lot on Highway 72

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft $32 SF/Yr

1.7 acre corner lot zoned for commercial, medical, residential.

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Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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Beaumont Centre Outparcel Opportunity

3199 Beaumont Centre Circle, Lexington, KY 40513

Contact for pricing

Outparcel opportunity in established shopping center for ground lease.

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Desoto County, MS Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Desoto County, MS with 3 listings featured on our commercial real estate exchange. The current inventory includes 7,314 square feet of properties with an estimated lease value of $68 SF/Yr.

Estimated lease rates for Medical Office Space in Desoto County, MS begin at $19 SF/Yr, with an average of $22 SF/Yr and extend to $28 SF/Yr.