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Lake St Louis, MO Office Spaces for Lease

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Weldon Spring, MO Dardenne Prairie, MO Chesterfield, MO Wentzville, MO Saint Charles, MO Town And Country, MO Ellisville, MO Wildwood, MO
31 properties
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Three-Suite Office Property
Updated: Jul 13
Three-Suite Office Property

1405 Jungermann Road, St Peters, MO 63376

$4,636/Mo
1,798 sqft 1.23 AC lot
Three office suites with two connected units
Separate bathroom and utility room for each suite
Approximately 60 open parking spaces
Covered walkway along the front of the suites
1.23‑acre site in St. Peters
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Lower-Level Retail Space
Updated: Jul 6
Lower-Level Retail Space

4053 N Saint Peters Parkway, St Peters, MO 63304

$960/Mo
1.84 AC lot
960 sf lower‑level suite at the rear of Signature Center
Two large open areas plus a break room and office area
Quick access to Hwy 94/364, I‑64, and I‑70
Ample open parking lot serving the retail center
1.842‑acre property with public water available
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All-Brick Professional Office Building
All-Brick Professional Office Building

O Fallon, MO 63368

$18 SF/Yr
5,892 sqft 0.16 AC lot

All-brick office building with 2,946 SF available for lease near Hwy K and US 64 in Keaton Corporate Park.

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Furnished Private Coworking Office
Furnished Private Coworking Office

8-22 Richmond Center Ct, Saint Peters, MO 63376

$1,200/Mo per office
260 sqft

Renovated workspace includes utilities, Wi-Fi, parking, and access to shared business amenities.

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Furnished Coworking Space
Furnished Coworking Space

1000 Mid Rivers Mall Drive Conference, St Peters, MO 63376

$129 SF/Yr
8,800 sqft

Furnished offices provide meeting, mailing, and shared workplace services.

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All-Brick Professional Office Building
All-Brick Professional Office Building

O Fallon, MO 63368

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2,946 sqft 0.16 AC lot

All-brick professional office building with space available for lease in Keaton Corporate Park near Hwy K and US 64.

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Modern Office Space for Lease
Modern Office Space for Lease

11400 Veterans Memorial Pkwy, Lake St Louis, MO 63367

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1,000 sqft

Flexible office suites with spacious floor plans, customizable layouts, and ample parking for convenient day-to-day operations.

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Renovated Medical Office Suites
Renovated Medical Office Suites

St Peters, MO 63376

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2,724 sqft

Newly renovated second-floor suites ranging from small to large medical or professional office configurations.

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Office Units with Covered Walkway
Office Units with Covered Walkway

C-1405 Jungermann Rd, Saint Peters, MO 63376

$4,636/Mo
1,798 sqft

Three finished office suites in a suburban business park with separate support areas and convenient regional highway access.

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Two-Story Medical Office Building
Two-Story Medical Office Building

St Peters, MO 63376

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18,763 sqft

Divisible office space includes signage, elevator access, and renovated suite and common-area interiors.

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Medical Office Suite with Monument Signage
Medical Office Suite with Monument Signage

O Fallon, MO 63368

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2,184 sqft

Medical office suite in a newer building with monument signage and building signage near local amenities.

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Fully Built-Out Medical Office Suite
Fully Built-Out Medical Office Suite

O Fallon, MO 63366

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1,707 sqft

Fully built-out 1,707 SF medical suite available in a multi-tenant retail building with monument and building signage.

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Office Units
Office Units

O Fallon, MO 63368

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10,600 sqft

Commercial office space suitable for professional users in a substantial multi-suite property.

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Class A Office Building Suite
Class A Office Building Suite

O Fallon, MO 63368

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1,825 sqft 4.63 AC lot

Class A office building offering upscale finishes within a well-maintained professional setting in O’Fallon’s business corridor.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

St Peters, MO 63376

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1,500 sqft

Move-in ready suite features four exam rooms, a waiting area, reception office, kitchenette, and separate bathroom.

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Medical/Professional Office Suite For Rent
Medical/Professional Office Suite For Rent

114 Piper Hill Dr, St Peters, MO

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7,180 sqft 1.00 AC lot

Medical/professional office suite available for lease with monument signage.

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Class A Office Building
Class A Office Building

O Fallon, MO 63368

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Corporate office setting with on-site fitness, café, parking, and prominent signage opportunities.

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St Peters Office Space Available
St Peters Office Space Available

4600 Executive Center Pkwy, St Peters, MO

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4,826 sqft 2.17 AC lot

Office space available in St Peters, move-in November 2025.

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O'Fallon Office Space Available
O'Fallon Office Space Available

O Fallon, MO

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966 sqft 1.33 AC lot

Office space available for lease in O'Fallon, Missouri.

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Furnished Coworking Offices
Furnished Coworking Offices

B-1000 Mid Rivers Mall Dr, Saint Peters, MO 63376

$300/Mo per office

Private workspaces offer shared business amenities, controlled entry, and convenient parking at a corner location.

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Office Space in St. Peters
Office Space in St. Peters

St Peters, MO

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870 sqft 2.31 AC lot

Office space available for lease in St. Peters, Missouri.

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O'Fallon Office Space Available
O'Fallon Office Space Available

O Fallon, MO

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2,000 sqft 0.23 AC lot

2000 square feet of office space for rent.

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Freestanding Office Building
Freestanding Office Building

O Fallon, MO 63366

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11,058 sqft

Freestanding office building with 8,053 SF main level, lower level space, and 71 parking spaces on a 1.44-acre lot.

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Built-to-Suit Medical Office
Built-to-Suit Medical Office

O Fallon, MO 63366

Contact for pricing
3,265 sqft

Built-to-suit medical office space with pylon signage exposure near Interstate 70 and Highway K.

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Lake St Louis, MO Office Spaces Lease Rates & Market Statistics

Explore 31 Office Spaces for lease in Lake St Louis, MO on Realmo, a commercial real estate exchange covering the Lake St Louis area. The current inventory totals 122,425 square feet of properties — an average of ~3,950 SF per listing.

Office Spaces lease rates in Lake St Louis range from $18 SF/Yr at the entry level to $129 SF/Yr at the top of the market, averaging $59.31 SF/Yr. That's a 7x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $59.31 SF/Yr, the local average runs 137% above Missouri's state average of $24.98 SF/Yr.

Lake St Louis accounts for 41% of the 76 office spaces currently available across St. Charles County, where nearby markets include Saint Charles and St Peters. By space type, the market includes 23 office units, 9 medical office space listings and 5 office buildings — office buildings typically offer the lowest entry point, while office units command the highest rates.

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