Add Listing
    Maine
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    York County, ME Office Spaces for Lease

    Notify Me
    List
    Map
    Portland, ME South Portland, ME Lewiston, ME
    33 results
    Medical Office Suite with Waiting Area
    $21 SF/Yr
    768 SF
    Medical Office Suite with Waiting Area

    62 Portland Rd, Kennebunk, ME 4043

    Well-appointed office spaces with a shared waiting area, suitable for therapist use and flexible suite configurations.
    • Well‑appointed office spaces with a common waiting area
    • Suitable for therapist use
    • Can be divided into a 500+ SF suite and a 268+ SF suite
    Updated: Jun 1
    View details
    Renovated Office Space Available
    $875/Mo
    1,500 SF
    Renovated Office Space Available

    860 Main St, Sanford, ME

    Renovated office space for lease with flexible configurations.
    • Newly renovated space with elegant gloss flooring and new heating/AC pumps.
    • Flexible configurations possible for office or retail use (600, 800, or 1500 +/- SF).
    • Excellent street visibility and ample signage space.
    • On‑site and street parking available.
    • Includes private offices, bathrooms, and a large open area.
    Updated: Nov 24, 2025
    View details
    Kennebunk Retail/Office Space Available
    $20 SF/Yr
    2,600 SF
    Kennebunk Retail/Office Space Available

    Retail and office suites available in Kennebunk's Lower Village.

    169 Port Rd, Kennebunk, ME

    View details
    Renovated Church Building Lower Level
    $11 SF/Yr
    7,651 SF
    Renovated Church Building Lower Level

    Renovated lower-level space with unique features available for lease.

    75 Bacon St, Biddeford, ME

    View details
    Saco Medical Office Suite
    $13 SF/Yr
    10,000 SF
    Saco Medical Office Suite

    10,000± SF medical office suite for rent.

    655 Main St, Saco, ME

    View details
    Flex/Office Building Near Route 1
    $1,750/Mo
    2,000 SF
    Flex/Office Building Near Route 1

    Multi-tenanted flex/office building with easy access to I-95.

    39 Limerick Rd, Arundel, ME

    View details
    Medical Office Condo For Lease
    $2,100/Mo
    1,088 SF
    Medical Office Condo For Lease

    Single-story medical office condo adjacent to SMHC Hospital.

    2 Medical Center Dr, Biddeford, ME

    View details
    Professional Office Suites For Rent
    $15 SF/Yr
    1,602 SF
    Professional Office Suites For Rent

    Professional office suites in high-traffic location near downtown Kennebunk.

    3-7 Webhannet Pl, Kennebunk, ME

    View details
    Kennebunk Office Space For Rent
    $27 SF/Yr
    3,134 SF
    Kennebunk Office Space For Rent

    Office space with open floor plan and architectural details.

    4 Main St, Kennebunk, ME

    View details
    York Office Space For Lease
    Contact for pricing
    3,200 SF
    York Office Space For Lease

    3,200 SF office space in the heart of York Town.

    16 Long Sands Rd, York, ME 3909

    View details
    York, ME Office Space
    $1,950/Mo
    900 SF
    York, ME Office Space

    Office space for lease in York, ME with parking.

    226 York Street, York, ME

    View details
    Retail/Office Space on Route 202
    $12 SF/Yr
    2,688 SF
    Retail/Office Space on Route 202

    Two-story retail or office space available for rent.

    400 Narragansett Trl, Buxton, ME

    View details
    Kennebunk Retail Development Opportunity
    $45 SF/Yr
    15,000 SF
    Kennebunk Retail Development Opportunity

    Proposed retail development with drive-thru and shop space available.

    70-72 Portland Rd, Kennebunk, ME

    View details
    Historic Mill Campus Commercial Space
    $16 SF/Yr
    630 SF
    Historic Mill Campus Commercial Space

    Revitalized mill campus offering flexible commercial suites for lease.

    2 Main St Ste 37-101, Biddeford, ME

    View details
    Downtown Saco Office Space Available
    $18 SF/Yr
    1,772 SF
    Downtown Saco Office Space Available

    Office/studio space for rent in downtown Saco.

    209 Main Street, Saco, ME

    View details
    Prime Retail Space in Sanford
    Contact for pricing
    Prime Retail Space in Sanford

    Commercial space with high visibility and foot traffic in Sanford.

    15 Washington St, Sanford, ME 4073

    View details
    Modern Office Spaces For Rent
    $850/Mo
    365 SF
    Modern Office Spaces For Rent

    Pristine office spaces ranging from 200 to 5200 sq ft.

    1 Alewive Park Rd, Kennebunk, ME

    View details
    Updated Office Suite in Sanford
    $8 SF/Yr
    11,000 SF
    Updated Office Suite in Sanford

    Recently updated office suite for sublease in South Sanford.

    1 Eagle Dr, Sanford, ME 4073

    View details
    End Cap Unit with Drive-Thru
    $20 SF/Yr
    2,240 SF
    End Cap Unit with Drive-Thru

    2,240 SF end cap unit with drive-thru for lease.

    28 Levesque Dr, Eliot, ME

    View details
    York Office Space For Lease
    $19 SF/Yr
    3,200 SF
    York Office Space For Lease

    3,200 SF office space in the heart of York.

    16 Long Sands Rd, York, ME 3909

    View details
    Downtown Biddeford Class A Office
    $28 SF/Yr
    64,800 SF
    Downtown Biddeford Class A Office

    New Class A office space in Biddeford, available Spring 2025.

    3 Lincoln Street, Biddeford, ME 4005

    View details
    Retail Outparcel For Lease
    $24 SF/Yr
    Retail Outparcel For Lease

    Retail outparcel available for lease.

    299 Elm St, Biddeford, ME 4005

    View details
    Waterboro Retail/Office Build-to-Suit Opportunity
    $25 SF/Yr
    3,250 SF
    Waterboro Retail/Office Build-to-Suit Opportunity

    Up to 30,000 SF available for retail or office.

    8 Dunkin Run, East, Waterboro, ME

    View details
    Retail/Office Build-to-Suit Opportunity
    $25 SF/Yr
    2,300 SF
    Retail/Office Build-to-Suit Opportunity

    Up to 2,300± SF retail/office space available for rent.

    40 Sokokis Trail, Waterboro, ME 4030

    View details

    York County, ME Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in York County, ME with 33 listings featured on our commercial real estate exchange. The current inventory includes 214,900 square feet of properties with an estimated lease value of $469 /Mo.

    Estimated lease rates for Office Spaces in York County, ME begin at $7 SF/Yr, with an average of $19 SF/Yr and extend to $45 SF/Yr.
    List
    Map

    Office Spaces by market

    Browse Office Spaces for Lease Near York, ME

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!