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    Saco, ME Office Spaces for Lease

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    Biddeford, ME Old Orchard Beach, ME Scarborough, ME
    6 listings
    Saco Medical Office Suite
    $13 SF/Yr
    10,000 SF
    Saco Medical Office Suite

    655 Main St, Saco, ME

    10,000± SF medical office suite for rent.
    • 10,000± SF medical office suite
    • Located just off I‑195 and Route One
    • Convenient to downtown Saco
    • Highly visible location
    • Second floor suite
    Updated: Oct 6, 2025
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    Downtown Saco Office Space Available
    $18 SF/Yr
    1,772 SF
    Downtown Saco Office Space Available

    209 Main Street, Saco, ME

    Office/studio space for rent in downtown Saco.
    • Prime downtown Saco location
    • On‑site parking available
    • 1,222± SF of 3rd floor office/studio space
    • Steps away from the Amtrak Downeaster
    • Easy access to I‑95
    Updated: May 6, 2025
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    Office Space for Lease
    Contact for pricing
    Office Space for Lease

    Office space available for lease at an industrial park address in Saco, ME.

    42 Industrial Park Rd, Saco, ME 4072

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    Saco Flex Space For Lease
    $13 SF/Yr
    4,590 SF
    Saco Flex Space For Lease

    Flex space suitable for office or medical office use.

    42 Industrial Park Rd, Saco, ME 4072

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    Retail/Athletic Space in Saco
    $16 SF/Yr
    Retail/Athletic Space in Saco

    Retail/athletic space in OA Sports Center complex, accessible from I-195.

    15 Lund Rd, Saco, ME 4072

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    Saco Flex Space Available
    $13 SF/Yr
    4,590 SF
    Saco Flex Space Available

    Flex space suitable for office or medical office use.

    42 Industrial Park Rd, Saco, ME 4072

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 6 Active listings in Saco, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Scarborough Medical/Office Space For Lease
    $13 SF/Yr
    1,049 SF
    Scarborough Medical/Office Space For Lease

    Class A office suites for lease in Scarborough, Maine.

    51 US Route 1, Scarborough, ME 4074

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    Downtown Biddeford Class A Office
    $28 SF/Yr
    64,800 SF
    Downtown Biddeford Class A Office

    New Class A office space in Biddeford, available Spring 2025.

    3 Lincoln Street, Biddeford, ME 4005

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    New Scarborough Town Center Development
    Contact for pricing
    New Scarborough Town Center Development

    Mixed-use development with retail, office, residential, and hospitality spaces.

    175 Scarborough Downs Rd, Scarborough, ME 4074

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    Downtown Biddeford Class A Office
    $28 SF/Yr
    64,800 SF
    Downtown Biddeford Class A Office

    New Class A office space available in Spring 2025.

    3 Lincoln St, Biddeford, ME 4005

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    Similar Spaces for Sale in Saco, ME

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Mixed-Use Retail and Office Building
    $649,000
    4,976 SF
    Mixed-Use Retail and Office Building

    Mixed-use property with two ground-floor retail units and two second-floor office spaces for flexible ownership or rental income.

    239 Main Street, Saco, ME 04072

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    Medical or Office Building
    $2,900,000
    10,260 SF
    Medical or Office Building

    Newer building with multiple office or medical configurations, classroom-style rooms, and ample on-site parking.

    5 Willey Road, Saco, ME 04072

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    Historic Brick Office Building
    $995,000
    8,736 SF
    Historic Brick Office Building

    Fully leased NNN office building with brick construction and a long-term tenant setup on Main Street in Saco.

    190 Main Street, Saco, ME 04072

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Pad Site for Lease
    Contact for pricing
    Prime Pad Site for Lease

    Highly visible 1.74 acre pad site in Belmont, NH.

    9 Old State Rd, Belmont, NH 3220

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    Lighted Intersection Commercial Land
    Contact for pricing
    Lighted Intersection Commercial Land

    Land lease opportunity on a high-traffic, lighted intersection with strong access for major development.

    3 Intervale Road, Concord, NH 03301

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    Riverfront Development Land
    Contact for pricing
    Riverfront Development Land

    Lease a portion of riverfront land with PD2 and RBV zoning for a range of potential commercial uses.

    Riverside Drive, Augusta, ME 04330

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    Leominster Commercial Development Site
    Contact for pricing
    Leominster Commercial Development Site

    1.4 acre corner lot available for ground lease.

    259-273 Lancaster St, Leominster, MA 1453

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    Saco, ME Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Saco, ME with 6 listings featured on our commercial real estate exchange. The current inventory includes 20,952 square feet of properties with an estimated lease value of $59 SF/Yr.

    Estimated lease rates for Office Spaces in Saco, ME begin at $13 SF/Yr, with an average of $14 SF/Yr and extend to $18 SF/Yr.
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