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    Mashpee, MA Office Spaces for Lease

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    10 properties
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    Single Office Unit
    Updated: Aug 10
    Single Office Unit

    681 Falmouth Road A25, Mashpee, MA 02649

    $495/Mo
    Unit A25 is a single office space
    Located at 681 Falmouth Road, Mashpee, MA 02649
    Positioned before Mashpee Commons
    Across from South Cape Plaza
    Property built in 1984
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    Single-Office Unit
    Updated: Aug 5
    Single-Office Unit

    A20d-681 Falmouth Rd, Mashpee, MA 02649

    $525/Mo
    Single office unit available
    A20D‑681 Falmouth Rd, Mashpee, MA
    Near Mashpee Commons
    Across from South Cape Plaza
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    Upper-Level Office Units
    Upper-Level Office Units

    A20h-681 Falmouth Rd, Mashpee, MA 02649

    $450-$525/Mo

    Individual office suites are available within Deer Crossing in Plaza.

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    Second-Floor Professional Office
    Second-Floor Professional Office

    681 Falmouth Rd, Mashpee, MA 02649

    Contact for pricing
    245 sqft

    Second-floor professional single office is available for lease within Deer Crossing Plaza.

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    Upper-Level Office Suites
    Upper-Level Office Suites

    681 Falmouth Road, Unit A20H, Mashpee, MA 02649

    $450/Mo

    Single offices A20H, A20C, and A20D are available for lease within an upper-level plaza office area.

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    Single Office For Lease
    Single Office For Lease

    681 Falmouth Road, Unit A20C, Mashpee, MA 02649

    $450/Mo

    Single office unit available for lease in Mashpee, MA.

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    Office Unit Space
    Office Unit Space

    681 Falmouth Rd, Mashpee, MA 02649

    Contact for pricing
    1,575 sqft

    Office unit with 1,575 SF available beginning February 1, 2026.

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    Retail Suite with Private Bath
    Retail Suite with Private Bath

    681 Falmouth Rd, Mashpee, MA 02649

    Contact for pricing
    1,725 sqft

    Flexible commercial space offers large rooms, signage opportunities, and a professional layout for office or retail use.

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    Second-Floor Walk-Out Office Space
    Second-Floor Walk-Out Office Space

    681 Falmouth Rd, Mashpee, MA 02649

    Contact for pricing
    1,100 sqft

    Second-floor walk-out office space with 1,100 SF and plenty of on-site parking near Deer Crossing.

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    Office Units For Lease
    Office Units For Lease

    681 Falmouth Rd, Mashpee, MA 02649

    Contact for pricing

    Two office units available for lease in Mashpee, Massachusetts.

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 10 Active listings in Mashpee, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail/Office Space Available
    Retail/Office Space Available

    77 Quaker Meeting House Rd, Sandwich, MA 02644

    $20 SF/Yr
    3,700 sqft 8.61 AC lot

    3,700+ SF retail/office space for lease.

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    Upper-Level Unit in Retail Complex
    Upper-Level Unit in Retail Complex

    178-180 Teaticket Hwy, Falmouth, MA 02536

    Contact for pricing
    1,300 sqft

    Updated renovated upper-level Unit 4 is available within a busy retail and office complex.

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    Second-Story Office Suites
    Second-Story Office Suites

    16 Jan Sebastian Dr, Sandwich, MA 02563

    $18 SF/Yr

    Flexible second-floor office suites offer multiple configurations for teams that need privacy or the option to combine space.

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    Prominent Office Space Available
    Prominent Office Space Available

    309 Teaticket Hwy, Falmouth, MA 02536

    Contact for pricing

    Second-story office space with ample parking and easy access.

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    Similar Spaces for Sale in Mashpee, MA

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Flexible Commercial Condo with Storage
    Flexible Commercial Condo with Storage

    68 Nicolettas, Mashpee, MA 02649

    $550,000
    2,464 sqft

    Commercial condo featuring showroom, office space, and fenced yard.

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    Single Office Unit
    Single Office Unit

    681 Falmouth Road Unit A20D, Mashpee, MA 02649

    Contact for pricing

    Compact office space within the Deer Crossing commercial property near established Mashpee retail destinations.

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    Single Office Unit
    Single Office Unit

    681 Falmouth Road Unit A25, Mashpee, MA 02649

    Contact for pricing

    Unit A25 is situated across from South Cape Plaza and near Mashpee Commons.

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    Mashpee, MA Office Spaces Lease Rates & Market Statistics

    Browse 10 Office Spaces for lease in Mashpee, MA on Realmo, a commercial real estate marketplace serving the Mashpee area. The current inventory totals 4,645 square feet of properties — an average of ~450 SF per listing.

    Asking lease rates for Office Spaces in Mashpee start at $450/Mo, average $482.50/Mo, and reach $525/Mo at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings.

    Mashpee accounts for 12% of the 84 office spaces currently available across Barnstable County, where nearby markets include Hyannis and Orleans.

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