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Palo Alto, CA Office Spaces for Lease

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131 properties
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Retail Space with Office Layout
Updated: Jun 3
Retail Space with Office Layout

353 University AVE, Palo Alto, CA 94301

$43,601/Mo
0.14 AC lot
6,014‑square‑foot retail space at University Avenue and Florence
Interior includes five offices, two restrooms, and a large main area
Central air conditioning
1972 construction with tar/gravel roof
Adjacent to Apple Store, Brandy Melville, Salt & Straw, and CVS Pharmacy
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Medical Office Suite with 6 Operatories
Updated: Sep 1
Medical Office Suite with 6 Operatories

555 Middlefield Road, Palo Alto, CA 94301

$7.50 SF/Yr
1,657 sqft
Approximately 1,657 SF dental office suite with six operatories
Adjacent suite allows expansion to approximately 2,742 square feet
Dedicated lab, reception and waiting areas, plus ample storage
Elevator‑served space in a modern, multi‑tenant building
Near Stanford University, Stanford Health Care, and Lucile Packard Children’s Hospital
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Office Units
Office Units

849 High St, Palo Alto, CA 94301

$6,320/Mo
6,320 sqft

Office accommodation is scheduled to become available on March 1, 2027.

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Ground-Floor Office Suite
Ground-Floor Office Suite

711 Colorado Ave, Palo Alto, CA 94303

$6 SF/Yr
2,629 sqft

Includes two ADA-compliant restrooms, a dedicated conference room, and kitchen space for a microwave and refrigerator.

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Sublease Office Space
Sublease Office Space

909 Alma St, Palo Alto, CA 94301

$9.75 SF/Yr
5,288 sqft

Office space is available for sublease at 909 Alma St with 5,288 SF of rentable area.

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Palo Alto Office Sublease Available
Palo Alto Office Sublease Available

101 University Avenue, Palo Alto, CA 94301

$6.50 SF/Yr
4,174 sqft

Sublease office space with workstations and parking near Caltrain.

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Palo Alto Office Space Available
Palo Alto Office Space Available

365 Page Mill Road, Palo Alto, CA 94306

$7.95 SF/Yr
85,000 sqft

Office space with fitness room, cafe, and ample parking.

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TI-Ready Lab Shell Office Space
TI-Ready Lab Shell Office Space

3450 Hillview Ave, Palo Alto, CA 94304

Contact for pricing
11,486 sqft

TI-ready lab shell with lab/office TIs available, divisible for flexible occupancy and easy Highway 280 access.

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Renovated Office Building
Renovated Office Building

499 Hamilton Avenue, Palo Alto, CA 94301

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7,862 sqft

Flexible office layout combines open work areas with private offices in downtown Palo Alto.

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Plug-and-Play Office Suite
Plug-and-Play Office Suite

3300 Hillview Ave, Palo Alto, CA 94304

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10,517 sqft

Modern technology-style upgrades with renovated lobby and restrooms, plus an outdoor area suited for meetings and events.

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Renovated Office Units With Patio
Renovated Office Units With Patio

Palo Alto, CA 94306

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4,700 sqft

Recently updated, move-in-ready workspace includes a private outdoor patio with BBQ.

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Office Suite with Private Office
Office Suite with Private Office

937-945 Industrial Avenue, Palo Alto, CA 94303

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3,500 sqft

Suite includes a private office, a large open work area, and fully HVAC’d interior space.

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Free-Standing Office Building
Free-Standing Office Building

1705 El Camino Real, Palo Alto, CA 94306

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11,128 sqft

Single-tenant office property with oversized windows, finished ceilings, a private patio, and secure parking.

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Office Units with Outdoor Seating
Office Units with Outdoor Seating

703-707 High St, Palo Alto, CA 94301

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3,393 sqft

Office accommodation includes on-site parking and an outdoor seating area.

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Ground-Floor Office Suite
Ground-Floor Office Suite

711-719 Colorado Ave, Palo Alto, CA 94303

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2,629 sqft

Seven private offices, a conference room, ADA-compliant restrooms, and kitchen space support a functional workplace layout.

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Open-Plan Office Units
Open-Plan Office Units

991 Commercial St, Palo Alto, CA 94303

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4,700 sqft

Open office layout with reserved parking and fire-sprinkler protection.

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Downtown Stand-Alone Office Building
Downtown Stand-Alone Office Building

636 Ramona Street, Palo Alto, CA 94301

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4,750 sqft

Standalone downtown office building with skylights, mostly furnished sit/stand workstations, and two on-site parking spaces.

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Coworking Space with Onsite Gym
Coworking Space with Onsite Gym

3307 Hillview Ave, Palo Alto, CA 94304

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39,138 sqft

Office and R&D configurations are available within a four-building campus with parking, transit shuttle service, and shared amenities.

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Renovated Flex Space with R&D Finishes
Renovated Flex Space with R&D Finishes

844 E Charleston Road, Palo Alto, CA 94303

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12,200 sqft

Standalone flex facility with open-plan office, engineering, and research-and-development functionality.

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Office Space for Lease
Office Space for Lease

116 University Ave, Palo Alto, CA 94301

Contact for pricing
3,364 sqft

Office space at 116 University Ave offers available suites ranging from 3,364 to 3,626 square feet.

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Office Units with EV Charging
Office Units with EV Charging

753 Alma St, Palo Alto, CA 94301

Contact for pricing
1,750 sqft

Office space includes meeting rooms, conference rooms, underground parking, and EV charging infrastructure.

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Class A Office Space Available
Class A Office Space Available

431 Waverley Street, Palo Alto, CA 94301

$9.95 SF/Yr
15,599 sqft

Prime downtown Palo Alto office space for lease.

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Creative Tech Space with Patios
Creative Tech Space with Patios

541-545 Bryant St, Palo Alto, CA 94301

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2,854 sqft

Loft-style creative space featuring rooftop patios and modern amenities.

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Class A Office Suites
Class A Office Suites

335 Bryant St, Palo Alto, CA 94301

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3,711 sqft

Elevator-served second and third floor suites with private office build-outs, kitchenettes, and restrooms.

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Palo Alto, CA Office Spaces Lease Rates & Market Statistics

Browse 131 Office Spaces for lease in Palo Alto, CA on Realmo, a commercial real estate marketplace serving the Palo Alto area. The current inventory totals 970,503 square feet of properties — an average of ~7,400 SF per listing.

Office Spaces lease rates in Palo Alto range from $5.95 SF/Yr at the entry level to $120 SF/Yr at the top of the market, averaging $20.62 SF/Yr. That's a 20x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $20.62 SF/Yr is 17% below the California state average of $24.77 SF/Yr.

Palo Alto accounts for 13% of the 993 office spaces currently available across Santa Clara County, where nearby markets include San Jose and Santa Clara. By space type, the market includes 105 office units, 20 office buildings and 7 creative space listings.

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