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    San Jose, CA Medical Office Space for Lease

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    Campbell, CA Santa Clara, CA Cupertino, CA
    12 results
    Move-in Ready Medical/Professional Suites
    $3 SF/Yr
    11,500 SF

    Move-in Ready Medical/Professional Suites

    244 N Jackson Avenue, San Jose, CA 95116

    Versatile suites near Regional Medical Center, ideal for medical practices.

    • Prime location directly across from Regional Medical Center
    • Move‑in ready suites designed for medical and professional services
    • Recent extensive upgrades including modernized HVAC, new flooring, fresh interior finishes, and resurfaced parking lot
    • Nine versatile suites with efficient layouts
    • Located within an established medical and neighborhood services cluster
    Updated: Apr 28
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    Medical Office Space Available
    $3 SF/Yr
    9,521 SF

    Medical Office Space Available

    393 Blossom Hill Road, San Jose, CA 95123

    Three-story medical office building with elevator access and highway access.

    • Exceptional visibility
    • Elevator served
    • Three‑story premier medical office building
    • Ideal for medical and dental uses
    • Easy access to Hwy 85
    Updated: Nov 22, 2025
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    Versatile Office and Medical Space
    Contact for pricing
    6,990 SF

    Versatile Office and Medical Space

    Adaptable office and medical space with parking in San Jose.

    1144 S 2nd St, San Jose, CA 95112
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    Evergreen District Medical Center
    Contact for pricing
    5,796 SF

    Evergreen District Medical Center

    Medical suites available for rent in Evergreen District.

    2365 Quimby Road, San Jose, CA 95122
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    Medical Office Space Available
    $3 SF/Yr
    1,292 SF

    Medical Office Space Available

    Medical office space near Regional Medical Center with easy highway access.

    280 N Jackson Ave, San Jose, CA
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    Professional Office Suite for Rent
    $2 SF/Yr
    1,186 SF

    Professional Office Suite for Rent

    Office suite featuring private offices, reception, and ample storage.

    1865 Alum Rock Ave, San Jose, CA
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    Medical Office Building For Rent
    $2 SF/Yr
    1,532 SF

    Medical Office Building For Rent

    Free-standing medical office building with 14 rooms and parking.

    242 La Pala Dr, San Jose, CA
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    San Jose Office Space Available
    $39 SF/Yr
    4,682 SF

    San Jose Office Space Available

    Office space for lease with possible medical office use.

    3097 Moorpark Ave, San Jose, CA
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    Turn-Key Medical/Professional Office Suite
    $21 SF/Yr
    1,392 SF

    Turn-Key Medical/Professional Office Suite

    Modern office suite ideal for medical, wellness, or professional practices.

    1693 Flanigan Dr, San Jose, CA 95121
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    Retail Space in San Jose
    $39 SF/Yr
    3,150 SF

    Retail Space in San Jose

    Retail space available in shopping center anchored by Lion Supermarket.

    1007 E Capitol Expy, San Jose, CA
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    Willow Glen Office Sublease Opportunity
    Contact for pricing
    7,200 SF

    Willow Glen Office Sublease Opportunity

    Office/medical space for sublease in Willow Glen, divisible to 1,800 SF.

    1690 SW Expy, San Jose, CA
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    Versatile Space in Central Location
    Contact for pricing

    Versatile Space in Central Location

    Adaptable commercial space with excellent access to transportation and amenities.

    25 N 14th St, San Jose, CA 95112
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    Based on your search, we've compiled 46 Potential Opportunities for your consideration. Besides 12 Active listings in San Jose, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 26 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical/Dental Office Space Available
    $3 SF/Yr
    1,296 SF

    Medical/Dental Office Space Available

    Medical/Dental office suite in Santa Clara, approximately 1,296 SF.

    2790 Newhall Street, Santa Clara, CA 95050
    View details
    Los Gatos Office Space Available
    $47 SF/Yr
    2,179 SF

    Los Gatos Office Space Available

    Professional office park in a premier west valley location.

    16615 Lark Ave, Los Gatos, CA
    View details
    Remodeled Medical Office Space
    $3 SF/Yr
    900 SF

    Remodeled Medical Office Space

    Medical office space with exam rooms near Good Samaritan Hospital.

    14547 S Bascom Ave, Los Gatos, CA
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    Iconic Santa Clara Plaza Retail/Office
    Contact for pricing

    Iconic Santa Clara Plaza Retail/Office

    Two-story building in Downtown Santa Clara near Santa Clara University.

    1171 Homestead Rd, Santa Clara, CA 95050
    View details

    Similar Spaces for Sale in San Jose, CA

    Consider Similar Space for Sale. We found 26 Spaces matching your search parameters.

    Renovated Office Building with Rentals
    $3,350,000
    2,390 SF
    Renovated Office Building with Rentals

    Renovated building with three rental units and wheelchair accessibility, positioned near Santana Row in San Jose.

    Address not disclosed, San Jose, CA 95128

    View details
    ADA-Accessible Office Building
    $6,900,000
    0.58 Acres
    ADA-Accessible Office Building

    ADA-compliant office building with elevator and fire alarm, positioned near a VTA light rail stop for flexible owner-use.

    480 N 1st ST, San Jose, CA 95112

    View details
    Ground-Level Medical Office Suite
    $799,999
    0.14 Acres
    Ground-Level Medical Office Suite

    Move-in-ready office suite with a reception area, private offices, and ample storage in a ground-level layout.

    2114 Senter RD 6, San Jose, CA 95112

    View details
    Turnkey Dental Office Suite
    $168,888
    0.10 Acres
    Turnkey Dental Office Suite

    Built-out dental space with reception, multiple operatories, and dental-ready plumbing for immediate, owner-user use.

    1692 Tully RD 18, San Jose, CA 95122

    View details
    San Jose Medical Office Building
    $1,995,000
    8,350 SF
    San Jose Medical Office Building

    Medical office building in downtown San Jose with four units.

    556 N 1st St, San Jose, CA 95112

    View details
    Evergreen San Jose Office Condo
    $848,000
    1,100 SF
    Evergreen San Jose Office Condo

    Spacious office condo in a thriving San Jose location.

    1569 Lexann Ave 224, San Jose, CA 95121

    View details
    Medical Office Condo For Sale
    $749,000
    1,600 SF
    Medical Office Condo For Sale

    Medical/professional office condo near O'Connor Hospital, San Jose.

    2039 Forest Ave 304, San Jose, CA 95128

    View details
    Alum Rock Professional Office Space
    $625,000
    1,454 SF
    Alum Rock Professional Office Space

    Commercial office space suitable for healthcare practices and other businesses.

    1863 Alum Rock Ave C, San Jose, CA 95116

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    Move-in Ready San Jose Office Suite
    $849,999
    1,568 SF
    Move-in Ready San Jose Office Suite

    Commercial office suite ideal for medical or professional use.

    2114 Senter Road #6, San Jose, CA 95112

    View details
    San Jose Commercial Building For Sale
    $1,899,999
    3,578 SF
    San Jose Commercial Building For Sale

    Commercial building in a bustling San Jose shopping center.

    2268 Senter Road 166, San Jose, CA 95112

    View details
    Evergreen San Jose Office Condo
    $848,000
    1,170 SF
    Evergreen San Jose Office Condo

    Spacious office condo in a thriving San Jose location.

    1569 Lexann Avenue #224, San Jose, CA 95121

    View details
    Medical/Professional Office Condo For Sale
    $749,000
    1,600 SF
    Medical/Professional Office Condo For Sale

    1,600 SF medical/professional office condo near O'Connor Hospital.

    2039 Forest Avenue #304, San Jose, CA 95128

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Grand Junction Commercial Land Lease
    $9,656/Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details
    Grand Junction Commercial Land Opportunity
    $17,728/Mo

    Grand Junction Commercial Land Opportunity

    1.36 acre commercial land for lease in Grand Junction.

    Sanford Drive, Grand Junction, CO 81505
    View details
    El Paso Commercial Land Lease
    $3,600/Mo

    El Paso Commercial Land Lease

    Commercial land for lease in a strategic El Paso location.

    5538 E Paisano Drive, El Paso, TX 79905
    View details
    Office Development Land For Lease
    Contact for pricing
    4,000 SF

    Office Development Land For Lease

    2.43 acres for office development with build-to-suit opportunity.

    1323 Strawfloor Drive, Jonesboro, AR 72401
    View details

    San Jose, CA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in San Jose, CA with 12 listings featured on our commercial real estate exchange. The current inventory includes 59,293 square feet of properties with an estimated lease value of $113 SF/Yr.

    Estimated lease rates for Medical Office Space in San Jose, CA begin at $2 SF/Yr, with an average of $14 SF/Yr and extend to $39 SF/Yr.
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    Browse Medical Office Space for Lease Near San Jose, CA

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    Most Searched ZIP Codes in San Jose, CA

    • 95112
    • 95116
    • 95121
    • 95122
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