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    La Mesa, CA Office Spaces for Lease

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    San Diego, CA Lemon Grove, CA Spring Valley, CA
    21 results
    Gateway Chula Vista
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    CA, Santee - Cuyamaca St
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    Private Office in Historic Building
    $650/Mo
    Private Office in Historic Building

    8200 Allison Ave, La Mesa, CA 91942

    Sublease private office with parking, utilities, and Wi-Fi.
    • Private office sublease in a historic building
    • Includes utilities, Wi‑Fi, and one parking space
    • High visibility location with potential for signage
    • Two windows that open for ventilation
    • Walking distance to restaurants, post office, and other amenities
    Updated: Apr 24
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    Boutique Medical Office Space
    $6 SF/Yr
    900 SF
    Boutique Medical Office Space

    5200 Lake Murray Blvd, La Mesa, CA

    Medical office space with pristine finishes and high-end aesthetics.
    • Prime location at a signalized intersection with I‑8 Freeway on‑ramp access.
    • Close proximity to major hospitals: Sharp Grossmont and UC San Diego Health East Campus Medical Center.
    • Turnkey medical office space with pristine finishes and high‑end aesthetics.
    • Newly renovated with fresh paint, new LED lighting, and new tile flooring.
    • Boutique medical office setting.
    Updated: Nov 25, 2025
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    La Mesa Office Space Available
    $2 SF/Yr
    2,058 SF
    La Mesa Office Space Available

    Office space for rent in La Mesa, California.

    7373 University Ave, La Mesa, CA

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    Turn-Key Office Suites Available
    $2 SF/Yr
    Turn-Key Office Suites Available

    Turn-key office suites with shared reception and waiting area.

    3855 Avocado Blvd, La Mesa, CA

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    Private Office in Historic Building
    $54 SF/Yr
    Private Office in Historic Building

    Private office space available for rent in historic building.

    8200 Allison Avenue, La Mesa, CA 91942

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    La Mesa Office/Retail Building
    $23 SF/Yr
    5,942 SF
    La Mesa Office/Retail Building

    Office/retail building available for sale in La Mesa, CA.

    8415 La Mesa Blvd, La Mesa, CA

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    La Mesa Office Property
    $5 SF/Yr
    La Mesa Office Property

    Fully leased office property in La Mesa, California.

    5400 Connecticut Ave, La Mesa, CA

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    La Mesa Office Space Available
    $1.75 SF/Yr
    1,100 SF
    La Mesa Office Space Available

    Office space available for rent in La Mesa, California.

    8911 La Mesa Blvd, La Mesa, CA

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    La Mesa Multi-Tenant Office
    $1.15 SF/Yr
    873 SF
    La Mesa Multi-Tenant Office

    Multi-tenant office building in La Mesa with ample parking.

    7484 University Ave, La Mesa, CA

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    La Mesa Office Space Available
    Contact for pricing
    2,524 SF
    La Mesa Office Space Available

    Office space for rent near Sharp Grossmont Hospital.

    5565 Grossmont Center Dr, La Mesa, CA

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    La Mesa Office Space Available
    $2 SF/Yr
    831 SF
    La Mesa Office Space Available

    831 square feet office space for rent in La Mesa.

    7777 Alvarado Rd, La Mesa, CA

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    La Mesa Contractor Storage Yard
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    La Mesa Contractor Storage Yard

    Contractor storage yard with warehouse and office space for lease.

    8100 Center Street, La Mesa, CA 91942

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    Office Space Available For Lease
    $21 SF/Yr
    Office Space Available For Lease

    Office space for lease at 7171 Alvarado Rd, La Mesa.

    7171 Alvarado Rd, La Mesa, CA 91942

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    La Mesa Retail/Office Space
    $27 SF/Yr
    La Mesa Retail/Office Space

    Retail and office spaces available for lease in La Mesa.

    5555 Jackson Dr, La Mesa, CA 91942

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    Medical Suite for Lease
    Contact for pricing
    3,343 SF
    Medical Suite for Lease

    Medical suite available for lease in La Mesa, California.

    8860 Center Dr, La Mesa, CA

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    La Mesa Retail/Office Building
    Contact for pricing
    6,862 SF
    La Mesa Retail/Office Building

    Two-story retail/office building in the heart of La Mesa.

    4730 3rd St, La Mesa, CA 91941

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    La Mesa Office Space Available
    $26 SF/Yr
    La Mesa Office Space Available

    Office units for rent in La Mesa, California.

    5575 Lake Park Way, La Mesa, CA 91942

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    Office Space for Lease
    Contact for pricing
    Office Space for Lease

    Office space available for lease in La Mesa, California.

    5360 Jackson Dr, La Mesa, CA 91942

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    Office Space Available For Lease
    $19 SF/Yr
    Office Space Available For Lease

    Office property available for lease.

    7853 El Cajon Blvd, La Mesa, CA 91941

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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 21 Active listings in La Mesa, CA, we suggest exploring alternatives. Similar 3 Properties for Sales.

    Similar Spaces for Sale in La Mesa, CA

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    La Mesa Village Twin-Home
    $1,650,000
    2,600 SF
    La Mesa Village Twin-Home

    Craftsman twin-home zoned for residential and commercial use.

    8318 Allison, La Mesa, CA 91942

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    Landmark Office Building in La Mesa
    Contact for pricing
    22,500 SF
    Landmark Office Building in La Mesa

    Three-story office building on a highly visible corner lot.

    7578 El Cajon Blvd, La Mesa, CA 91942

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    Freeway-Visible Medical Building For Sale
    $6,950,000
    10,000 SF
    Freeway-Visible Medical Building For Sale

    Two-story, 10,000 SF medical building with freeway visibility.

    7051 Alvarado Rd, La Mesa, CA 91942

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    La Mesa, CA Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in La Mesa, CA with 21 listings featured on our commercial real estate exchange. The current inventory includes 12,192 square feet of properties with an estimated lease value of $147 SF/Yr.

    Estimated lease rates for Office Spaces in La Mesa, CA begin at $1.15 SF/Yr, with an average of $16 SF/Yr and extend to $54 SF/Yr.
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    Most Searched ZIP Codes in La Mesa, CA

    • 91942
    • 91941

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