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Mount Pleasant, SC Office Buildings for Lease

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11 results
Class A Medical Office Building
$28 SF/Yr
14,084 SF

Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

Renovated medical/office building with ample parking in Mt. Pleasant.

  • Fully renovated, Class A office building with 45,258 RSF
  • Ample parking at 4.5/1000
  • First floor fully leased, including MUSC
  • Generous tenant upfit allowance provided by landlord
  • Ready for tenant upfit to suit
Updated: Mar 25
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New Office Building in Mount Pleasant
$37 SF/Yr
9,849 SF

New Office Building in Mount Pleasant

1681 Belle Isle Ave, Mount Pleasant, SC

Newly constructed office building in desirable Mount Pleasant location.

  • Newly constructed, 40,000 SF, two‑story office building.
  • Located in the desirable Long Point Road submarket of Mount Pleasant.
  • Convenient access to I‑526.
  • Strong demographics in the surrounding area.
  • Surrounded by amenities at Belle Hall Shopping Center.
Updated: Aug 28, 2025
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Mount Pleasant Office Park Space
Contact for pricing
1,245 SF

Mount Pleasant Office Park Space

Office park with visibility, access, and nearby amenities for rent.

782 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464
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Freestanding Office Building For Lease
$20 SF/Yr
3,400 SF

Freestanding Office Building For Lease

Two-story office property in a rapidly developing commercial corridor.

890 JOHNNIE DODDS BLVD, Mount Pleasant, SC
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Class A Office Space Available
$45 SF/Yr
3,700 SF

Class A Office Space Available

Class A office space for rent in Mount Pleasant.

Bridgeside Blvd, Mount Pleasant, SC
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Class A Office Space Available
Contact for pricing

Class A Office Space Available

Class A office space for lease or sale in Mount Pleasant.

550 Long Point Road, Mount Pleasant, SC 29464
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Mount Pleasant Class A Office
Contact for pricing

Mount Pleasant Class A Office

Class A office building in central Mount Pleasant location.

735 Johnnie Dodds Blvd, Mt Pleasant, SC 29464
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Class-A Office Building For Lease
Contact for pricing
65,000 SF

Class-A Office Building For Lease

Class-A office building with stunning views and modern design.

Mount Pleasant, SC 29464
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Renovated Office/Medical Space Available
Contact for pricing
44,958 SF

Renovated Office/Medical Space Available

High-end commercial building in a rapidly growing area.

1200 Innovation Wy, Mt Pleasant, SC 29466
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Mt Pleasant Office Building For Rent
$30 SF/Yr

Mt Pleasant Office Building For Rent

Two-story office building with high visibility and easy access.

880 Johnnie Dodds Blvd, Mt Pleasant, SC 29464
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Professional Office Building For Rent
Contact for pricing
4,238 SF

Professional Office Building For Rent

Professional office building in prime location with walkable amenities.

845 Lowcountry Blvd, Mt Pleasant, SC 29464
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Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 11 Active listings in Mount Pleasant, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Explore Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office Building Near Charleston Amenities
$26 SF/Yr
7,150 SF

Office Building Near Charleston Amenities

Three-story office building near I-26 and I-526.

1360 Truxtun Ave, North Charleston, SC
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Furnished Office Building Sublease Opportunity
$24 SF/Yr
78,394 SF

Furnished Office Building Sublease Opportunity

Well-appointed, fully furnished office building available for sublease.

125 Fairchild Street, Charleston, SC, USA, Charleston, SC 29492
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Renovated Class A Office Building
$32 SF/Yr

Renovated Class A Office Building

Three-story office building with high-end finishes, available April 2026.

4055 Faber Place Drive # 104, North Charleston, SC 29405
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Daniel Island Office Sublease Opportunity
Contact for pricing

Daniel Island Office Sublease Opportunity

Sublease opportunity in Blackbaud's Daniel Island headquarters.

65 Fairchild St, Charleston, SC 29492
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Explore Similar Spaces for Sale in Mount Pleasant, SC

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

New Office Building For Sale
Contact for pricing
10,000 SF

New Office Building For Sale

New 10,000 SF office building in Mount Pleasant, SC.

1214 Chuck Dawley Blvd, Mount Pleasant, SC 29464
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Multi-Tenant Office Building For Sale
$2,600,000
7,486 SF

Multi-Tenant Office Building For Sale

Multi-tenant office building with modern lease options and high visibility.

1124 Park West Boulevard, Mount Pleasant, SC 29466
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Two-Story Office Building For Sale
Contact for pricing
3,166 SF

Two-Story Office Building For Sale

Two-story office building with Class A finishes and surface parking.

268 West Coleman Boulevard, Mount Pleasant, SC 29464
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Mount Pleasant Office Building For Sale
$6,700,000
14,342 SF

Mount Pleasant Office Building For Sale

Office building for sale with strong tenant in Mount Pleasant.

985 Johnnie Dodds Blvd, Mount Pleasant, SC
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Class A Mixed-Use Asset
Contact for pricing
63,061 SF

Class A Mixed-Use Asset

63,061 SF mixed-use property in Mount Pleasant, SC.

766 S Shelmore Blvd, Mount Pleasant, SC 29464
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Mount Pleasant Office Building For Sale
$6,000,000
20,560 SF

Mount Pleasant Office Building For Sale

Class A office building near I-526 with development potential.

550 Long Point Rd, Mount Pleasant, SC 29464
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Mount Pleasant Office Investment
$3,550,000
9,649 SF

Mount Pleasant Office Investment

Suburban office building in central Mount Pleasant with existing income.

975 Johnnie Dodds Blvd, Mount Pleasant, SC
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Build-to-Suit Opportunity
$4,000/Mo
2,400 SF

Commercial Land Build-to-Suit Opportunity

Commercial land available for build-to-suit in Jacksonville, NC.

2683 Henderson Drive, Jacksonville, NC 28546
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Commercial Space on Trent Boulevard
$1,200/Mo
1,000 SF

Commercial Space on Trent Boulevard

Versatile commercial space ready for customization in a prime location.

3709 Trent Road, New Bern, NC 28562
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Prime Commercial Lot For Lease
$7,500/Mo

Prime Commercial Lot For Lease

0.66 acre commercial lot in high-traffic area.

Tift Avenue N, Tifton, GA 31794
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Melbourne Land for Ground Lease
Contact for pricing

Melbourne Land for Ground Lease

1.2-acre development site in Viera/Suntree area available for lease.

6365 N. Wickham Road, Melbourne, FL 32940
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Mount Pleasant, SC Office buildings Leasing Opportunities Market Analysis

Explore Office buildings leasing options in Mount Pleasant, SC with 11 listings featured on our commercial real estate exchange. The current inventory includes 1,042,521,480 square feet of properties with an estimated lease value of $65 SF/Yr.

Estimated lease rates for Office buildings in Mount Pleasant, SC begin at $28 SF/Yr, with an average of $32 SF/Yr and extend to $37 SF/Yr.
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