Mount Pleasant, SC Office buildings for Rent & Lease

Updated: Mar 25

Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

$28 SF/Yr

14,084 sqft

Fully renovated, Class A office building with 45,258 RSF
Ample parking at 4.5/1000
First floor fully leased, including MUSC
Generous tenant upfit allowance provided by landlord
Ready for tenant upfit to suit

View details

Updated: Aug 25, 2025

Freestanding Office Building For Lease

890 JOHNNIE DODDS BLVD, Mount Pleasant, SC

$20.50 SF/Yr

3,400 sqft

Located in the rapidly developing Johnnie Dodds commercial corridor.
Freestanding, 2‑story office property.
Suitable for a number of different office uses.
Located in Mount Pleasant, which has experienced rapid residential and commercial development.
Past tenants include real estate developers, therapists and other professional service providers.

View details

Professional Office Building with Parking

845 Lowcountry Boulevard # A, Mount Pleasant, SC 29464

Contact for pricing

4,238 sqft

Office suites with windows, shared conference space, and free on-site parking in a high-visibility corridor.

View details

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Two-Story Office Building

1501 Belle Isle Avenue Suite 240, Mount Pleasant, SC 29464

Contact for pricing

40,000 sqft

Newly constructed two-story office building with modern interior and exterior finishes near I-526 access.

View details

Class A Office Space Available

Mt Pleasant, SC 29464

$20 SF/Yr

Class A office space for lease or sale in Mount Pleasant.

View details

Professional Office Building For Rent

845 Lowcountry Blvd, Mt Pleasant, SC 29464

Contact for pricing

4,238 sqft

Professional office building in prime location with walkable amenities.

View details

Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 6 Active listings in Mount Pleasant, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Class A Office Building

3875 Faber Place Drive, North Charleston, SC 29405

$25 SF/Yr

15,224 sqft

Class A office building with common area upgrades and efficient layouts.

View details

Fully Furnished Sublease Office Building

125 Fairchild Street #1st Floor, Charleston, SC 29492

Contact for pricing

78,000 sqft

Three-floor office building with open layout and meeting areas; floors can be subdivided.

View details

Renovated Class A Office Building

4055 Faber Place Drive # 104, North Charleston, SC 29405

$32 SF/Yr

Three-story office building with high-end finishes, available April 2026.

View details

Daniel Island Office Sublease Opportunity

65 Fairchild St, Charleston, SC 29492

Contact for pricing

Sublease opportunity in Blackbaud's Daniel Island headquarters.

View details

Similar Spaces for Sale in Mount Pleasant, SC

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Retail Showroom and Office Building

2365 N Highway 17, Mount Pleasant, SC 29466

$1,295,000

3,298 sqft

Renovated two-story building with retail showroom and offices, featuring multiple workspaces, kitchen, and restrooms with strong Hwy 17 visibility.

View details

Mount Pleasant Office Building For Sale

550 Long Point Rd, Mount Pleasant, SC 29464

$6,000,000

20,560 sqft

Class A office building near I-526 with development potential.

View details

Two-Story Office Building For Sale

268 West Coleman Boulevard, Mount Pleasant, SC 29464

Contact for pricing

3,166 sqft

Two-story office building with Class A finishes and surface parking.

View details

Class A Mixed-Use Asset

766 S Shelmore Blvd, Mount Pleasant, SC 29464

Contact for pricing

63,061 sqft 9.24 AC lot

63,061 SF mixed-use property in Mount Pleasant, SC.

View details

Office Building For Sale

1415 Stuart Engals Blvd, Mount Pleasant, SC 29464

Contact for pricing

8,855 sqft

For sale office building offering 8,855 SF of space.

View details

Office Building For Sale

816 Johnnie Dodds Blvd, Mount Pleasant, SC 29464

Contact for pricing

8,800 sqft

Office building offered for sale with approximately 8,800 square feet of space.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Build-to-Suit Opportunity

2683 Henderson Drive, Jacksonville, NC 28546

$4,000/Mo

2,400 sqft

Commercial land available for build-to-suit in Jacksonville, NC.

View details

Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

View details

Prime Commercial Lot For Lease

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

0.66 acre commercial lot in high-traffic area.

View details

Cleared Lot in Williston

33 NW 3RD St, Williston, FL 32696

$20,000/Mo

C2-zoned lot in Williston's central business area for rent.

View details