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    Sanford, FL Office Buildings for Lease

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    Frontage Office Building with Parking
    Updated: Apr 29, 2025
    Frontage Office Building with Parking

    500 E AIRPORT Boulevard, Sanford, FL 32773

    $7,495/Mo
    5,124 sqft
    GC2 commercial building with 5,124 SF and over 350 ft of frontage on busy E Airport Blvd in Sanford
    Office layout currently divided into 7 oversized rooms, with possibility to section further if desired
    Includes 2 bathrooms, kitchenette with attached eating space, and a laundry room with multiple sinks and hookups
    On‑site private parking lot with 42 spaces, plus a 2‑car carport
    Central heating and central air; appliances include washer, dryer, and refrigerator
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    Commercial Office Building
    Updated: Apr 29, 2025
    Commercial Office Building

    502 E AIRPORT Boulevard, Sanford, FL 32773

    $2,495/Mo
    2,641 sqft
    2,641 heated SF GC2 commercial office building built in 1962, located right off a busy road
    Office layout includes an entry lobby with reception area, four large offices, and two bathrooms
    Brand new roof installed May 2025
    Central air and central electric heating
    Appliances included: washer, dryer, and refrigerator
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    Freestanding Office Building with Parking
    Freestanding Office Building with Parking

    806 E 25TH Street, Sanford, FL 32771

    $2,900/Mo
    2,037 sqft

    Freestanding, fully furnished office layout with 7 front parking spaces and multiple private offices.

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    Renovated Office Building in Sanford
    Renovated Office Building in Sanford

    1256 - 1280 Upsala Road |, Sanford, FL 32771

    $17.50 SF/Yr
    23,700 sqft

    Recently renovated office building with modern amenities and prime location.

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    Versatile Commercial Office Building For Rent
    Versatile Commercial Office Building For Rent

    502 E AIRPORT Blvd, Sanford, FL 32773

    $29,940 SF/Yr
    2,641 sqft

    2641 sq ft office building with reception and offices.

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    Freestanding Commercial Building with Drive-Thru
    Freestanding Commercial Building with Drive-Thru

    1381 Rinehart Road, Sanford, FL 32771

    Contact for pricing
    5,301 sqft

    Freestanding building with drive-thru lanes and ample on-site parking; visibility from Rinehart Road.

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    Spacious Sanford Commercial Building For Rent
    Spacious Sanford Commercial Building For Rent

    500 E Airport Blvd, Sanford, FL 32773

    $89,940 SF/Yr
    5,124 sqft

    5124 sq ft commercial building with high-traffic frontage.

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    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 7 Active listings in Sanford, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Office buildings for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Lake Mary Office Space Available
    Lake Mary Office Space Available

    3300 West Lake Mary Blvd, Lake Mary, FL 32746

    $18.75 SF/Yr
    28,183 sqft

    28,183± SF office space in Lake Mary, excellent location.

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    Longwood Office Building with Storage
    Longwood Office Building with Storage

    1130 N RONALD REAGAN Blvd, Longwood, FL 32750

    $42,000 SF/Yr
    1,800 sqft

    Versatile office building with flexible space and storage lot.

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    Multitenant Medical Office Building
    Multitenant Medical Office Building

    4095 County Road 46A, Lake Mary, FL 32746

    Contact for pricing
    23,319 sqft

    A flexible medical office development with up to nine suites and on-site parking for patient convenience.

    View details
    Longwood Office Building For Rent
    Longwood Office Building For Rent

    2009 Longwood Lake Mary Rd, Longwood, FL 32750

    $2,323/Mo

    Office building in Longwood/Lake Mary area, multiple units available.

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    Similar Spaces for Sale in Sanford, FL

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Renovation-Ready Office Building on Double Lot
    Renovation-Ready Office Building on Double Lot

    3316 W 5TH Street, Sanford, FL 32771

    $425,000
    1,360 sqft 0.19 AC lot

    Structure renovations are currently in progress on a double lot, with conversion options for professional or medical office use.

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    Renovated Office Building on Double Lot
    Renovated Office Building on Double Lot

    3316 W 5TH STREET, Sanford, FL 32771

    $425,000
    1,360 sqft

    Double-lot office building renovation offers flexible layout for professional and medical use with convenient highway access.

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    Fenced Industrial Flex Facility
    Fenced Industrial Flex Facility

    414 W 9TH Street, Sanford, FL 32771

    $684,900
    1,740 sqft 0.43 AC lot

    Industrial flex property includes offices, conference space, and direct access warehouse/storage, plus secure fenced outdoor storage.

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    Remodeled Historic Downtown Office Building
    Remodeled Historic Downtown Office Building

    121 E 1st Street, Unit 101, Sanford, FL 32771

    $1,500,000
    8,008 sqft

    Remodeled two-story building with open first floor, eight offices upstairs, and new HVAC installed in 2023.

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    Redevelopment Land with Existing Structure
    Redevelopment Land with Existing Structure

    3312 W 5TH Street, Sanford, FL 32771

    $375,000
    936 sqft 0.16 AC lot

    For sale in Sanford, Florida, with an existing structure on a small lot and access to major roadways.

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    Freestanding Office Building
    Freestanding Office Building

    806 E 25TH Street, Sanford, FL 32771

    $399,900
    2,037 sqft 0.24 AC lot

    Freestanding concrete block office building with designated front parking and furnished interior layout.

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    Sanford Historic District Office Building
    Sanford Historic District Office Building

    720 S PARK AVENUE, Sanford, FL 32771

    $679,000
    1,938 sqft

    Charming Mediterranean-style office building in Sanford's Historic District.

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    New Sanford Professional/Medical Office Building
    New Sanford Professional/Medical Office Building

    1300 LEXINGTON GREEN LANE, Sanford, FL 32771

    $899,000
    0.08 AC lot

    New construction professional/medical office building available for immediate occupancy.

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    Sanford Commercial Building For Sale
    Sanford Commercial Building For Sale

    333 GORDON St, Sanford, FL 32771

    $949,000

    Free-standing commercial building near Downtown Sanford with easy highway access.

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    Redevelopment Land with Office Structure
    Redevelopment Land with Office Structure

    3312 W 5TH St, Sanford, FL 32771

    $375,000

    Land with an existing structure offers redevelopment flexibility with convenient access to major Sanford routes.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Melbourne Land for Ground Lease
    Melbourne Land for Ground Lease

    6365 N. Wickham Road, Melbourne, FL 32940

    $36 SF/Yr

    1.2-acre development site in Viera/Suntree area available for lease.

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    Cleared Lot in Williston
    Cleared Lot in Williston

    33 NW 3RD St, Williston, FL 32696

    $20,000/Mo

    C2-zoned lot in Williston's central business area for rent.

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    Prime Corner Land For Sale
    Prime Corner Land For Sale

    2305 N NEBRASKA Avenue, Tampa, FL 33602

    $6,000/Mo

    Corner lot near downtown Tampa with high visibility and access.

    View details
    Commercial Land with US-41 Frontage
    Commercial Land with US-41 Frontage

    14500 N CLEVELAND Avenue, North Fort Myers, FL 33903

    $10,416/Mo

    Two adjacent commercial parcels totaling about 1.85 acres along US-41 in North Fort Myers.

    View details

    Sanford, FL Office buildings Market Trends and Statistics

    Explore Office buildings leasing options in Sanford, FL with 7 listings featured on our commercial real estate exchange. The current inventory includes 41,267 square feet of properties with an estimated lease value of $119,943.

    Estimated lease rates for Office buildings in Sanford, FL begin at $11.34 SF/Yr, with an average of $19,990 /Mo and extend to $89,940.
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