Sanford, FL Medical Office Space for Rent & Lease

Updated: Jan 27

Office Units with Build-to-Suit Options

500 W LAKE MARY Boulevard, Sanford, FL 32773

$18 SF/Yr

90,008 sqft 9.51 AC lot

Office suites from 1,400 to 35,000 square feet
Approximately 25,000 square feet on the second floor is divided into smaller spaces
Build‑to‑suit configurations available
90,008‑square‑foot, three‑story building on 9.51 acres
Lake Mary Boulevard frontage with on‑site parking

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Updated: Jan 27

Multi-Suite Office Building

500 W LAKE MARY Boulevard, Sanford, FL 32773

$18 SF/Yr

90,008 sqft 9.51 AC lot

90,008‑square‑foot office property on 9.51 acres
25,000 SF second floor divided into smaller spaces
Suite sizes range from 1,400 to 35,000 square feet
Build‑to‑suit configurations available
Three‑story building with elevators and ample parking

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Multi-Unit Office Property

500 W Lake Mary Boulevard Unit 301, Sanford, FL 32773

$18 SF/Yr

90,008 sqft

Flexible office suites with build-to-suit options, elevator access, on-site parking, and modified gross lease structure.

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Renovated Medical Office Space

2209 South French Avenue, Sanford, FL 32771

$30 SF/Yr

Medical office space with on-site parking, business signage, and immediate occupancy availability.

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First-Floor Office Space

217 S OAK, Sanford, FL 32771

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Private offices, reception space, kitchenette, two restrooms, and parking support varied business layouts.

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Elevator-Served Office Units

500 W LAKE MARY 301, Sanford, FL 32773

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Professionally managed office center offering build-to-suit suites with flexible configurations and on-site parking.

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Reflections Office Units

500 W LAKE MARY BLVD, Sanford, FL 32773

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The complex accommodates professional, educational, medical, retail, and food-service uses.

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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 7 Active listings in Sanford, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Freestanding Office Building

221 W STATE ROAD 434, Longwood, FL 32750

$7,950/Mo

4,549 sqft 0.63 AC lot

Flexible commercial building with private offices, open work areas, kitchen, and multiple bathrooms.

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Single-Story Office Park

1404-1436 North Ronald Reagan Blvd, Longwood, FL 32750

$18 SF/Yr

Move-in-ready office suites within a professionally managed, single-story park with strong boulevard visibility and signage.

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Upgraded Medical Office Suite

205-4106 W Lake Mary Blvd, Lake Mary, FL 32746

Contact for pricing

1,990 sqft

Modern medical office condominium with reception space, private offices, shared restrooms, and on-site parking.

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Lake Mary Medical Office Space

1141 Patterson Ter, Lake Mary, FL

Contact for pricing

8,266 sqft 0.24 AC lot

Medical office space with exam rooms and convenient highway access.

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Similar Spaces for Sale in Sanford, FL

Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

Freestanding Medical Office

2105 S PARK Avenue, Sanford, FL 32771

$549,000

1,550 sqft 0.28 AC lot

Standalone medical office with private parking, a fenced yard, and PD zoning along Park Avenue.

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Standalone Medical Office Building

2105 S PARK AVENUE, Sanford, FL 32771

$549,000

1,550 sqft

Former pediatric practice with private parking and a fenced yard.

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Dental Office Retail Storefront

146-2921 S Orlando Dr, Sanford, FL 32773

$649,900

2,000 sqft

Custom five-operatory dental office with digital X-ray equipment in a busy strip mall storefront with ample parking.

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Dental Office in Busy Center

2921 S ORLANDO DRIVE #146, Sanford, FL 32773

$649,900

2,000 sqft 0.05 AC lot

Retail storefront dental office in a busy shopping center.

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Office Unit in Reflections Complex

500 W LAKE MARY BLVD, Sanford, FL 32773

Contact for pricing

1,470 sqft 1.50 AC lot

A 1987 office property offers adaptable space for professional, medical, educational, and select retail or food-service uses.

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Medical Office Building

1400 S Park Ave, Sanford, FL 32771

Contact for pricing

2,150 sqft

Healthcare-oriented property in Sanford’s Historic District with connectivity to US-17-92, SR-46, and Interstate 4.

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Sanford Medical Building Opportunity

1204 HISTORIC GOLDSBORO Blvd, Sanford, FL 32771

$194,900

0.05 AC lot

Concrete block medical building in rapidly expanding Sanford.

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Office Building Under Renovation

3316 W 5TH, Sanford, FL 32771

$410,000

Existing commercial structure offers a customizable setting for office, medical, or legal use.

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Dental Office in Busy Center

2921 S ORLANDO Dr 146, Sanford, FL 32773

$649,900

Retail storefront dental office in a high-traffic shopping center.

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Concrete Block Medical Office Building

1204 HISTORIC GOLDSBORO Boulevard, Sanford, FL 32771

$194,900

1,360 sqft 0.05 AC lot

Medical office property with central air conditioning and GC2 zoning in Sanford.

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Sanford, FL Medical Office Space Lease Rates & Market Statistics

Explore 7 Medical Office Space listings for lease in Sanford, FL on Realmo, a commercial real estate exchange covering the Sanford area. The current inventory totals 270,024 square feet of properties.

Asking lease rates for Medical Office Space in Sanford start at $18 SF/Yr, average $21 SF/Yr, and reach $30 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $21 SF/Yr is 25% below the Florida state average of $27.91 SF/Yr.

Sanford accounts for 15% of the 46 medical office space listings currently available across Seminole County, where nearby markets include Oviedo and Lake Mary. Medical Office Space listings make up 16% of the 44 Office Spaces currently for lease in Sanford, with asking rates averaging $21 SF/Yr — 46% below the citywide Office Spaces average of $38.94 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (37 listings) and Office buildings (6 listings) elsewhere in the Sanford market.