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Sanford, FL Office Properties & Spaces for Sale

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28 results
Versatile Sanford Commercial Complex
$825,000
4,493 SF

Versatile Sanford Commercial Complex

2516 SANFORD AVENUE, Sanford, FL 32773

Three-building complex with restaurant, live/work space, and flex building.

  • Prime location near the intersection of Sanford Ave and 25th St, a high‑traffic commercial corridor.
  • Three buildings on 0.71 acres offering multiple income streams and business opportunities.
  • Building 1: A 2,583 SF turnkey restaurant with existing equipment included.
  • Building 2: Unique live/work space with a 400 SF apartment above 400 SF of flex space.
  • Building 3: 1,110 SF flex building adaptable for various uses.
Updated: Dec 2, 2025
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Remodeled Historic Sanford Mixed-Use Building
$2,235,000
7,987 SF

Remodeled Historic Sanford Mixed-Use Building

121 E 1ST STREET, Sanford, FL 32771

Remodeled historic building in Downtown Sanford's vibrant First Street district.

  • Prime location in Downtown Sanford's First Street business district with high visibility.
  • Remodeled historic commercial building blending modern functionality with original character (exposed brick, soaring ceilings).
  • Versatile open‑concept first floor suitable for retail, restaurant, office, or event space.
  • Professionally designed second floor with eight private offices, a break room, and a restroom.
  • Recent upgrades including new LVP flooring, new carpet, fresh paint, and a new A/C system (2023).
Updated: Oct 27, 2025
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Sanford Mixed-Use Commercial Opportunity
$289,000
1,332 SF

Sanford Mixed-Use Commercial Opportunity

Versatile commercial space in Sanford with high visibility and parking.

1013 HISTORIC GOLDSBORO BOULEVARD, Sanford, FL 32771
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Prime Sanford Commercial/Mixed-Use Land
$349,900
0.76 Acres

Prime Sanford Commercial/Mixed-Use Land

Versatile commercial property near downtown Sanford with redevelopment potential.

420 MONROE ROAD, Sanford, FL 32771
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Commercial Property on Orlando Drive
$825,000
1,716 SF

Commercial Property on Orlando Drive

Mixed-use commercial property with high traffic and flexible zoning.

2606 S ORLANDO DRIVE, Sanford, FL 32773
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Sanford Waterfront Commercial Property
$889,000
2,152 SF

Sanford Waterfront Commercial Property

Prime commercial property in Sanford's thriving waterfront district.

417 & 419 SANFORD AVENUE, Sanford, FL 32771
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Versatile Sanford Commercial Complex
$825,000
4,493 SF

Versatile Sanford Commercial Complex

Three-building complex with restaurant, live/work unit, and flex space.

2516 SANFORD AVENUE, Sanford, FL 32773
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Commercial Building Near Downtown Sanford
$949,000
3,360 SF

Commercial Building Near Downtown Sanford

Free-standing commercial building with high visibility and flexible use.

333 GORDON STREET, Sanford, FL 32771
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Historic Downtown Sanford Commercial Spaces
$3,400,000
0.37 Acres

Historic Downtown Sanford Commercial Spaces

Restaurant, retail, and office spaces in desirable downtown location.

201 W 1ST St, Sanford, FL 32771
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Medical Office Building For Sale
$1,075,000
3,452 SF

Medical Office Building For Sale

Free-standing medical office building with ample parking and highway access.

261 E AIRPORT BOULEVARD, Sanford, FL 32773
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Sanford Commercial Building on US 17-92
$3,499,000
21,240 SF

Sanford Commercial Building on US 17-92

Former furniture store with showroom, warehouse, and office space.

650 Lake Minnie Dr, Sanford, FL 32773
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Downtown Sanford Historic Brick Building
$2,000,000
5,670 SF

Downtown Sanford Historic Brick Building

Renovated mixed-use building in Sanford's Historic District.

108 S Park Ave, Sanford, FL
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Historic Mixed-Use Landmark in Sanford
$2,000,000
5,204 SF

Historic Mixed-Use Landmark in Sanford

Historic mixed-use building in Downtown Sanford with flexible configurations.

101 W 1st St, Sanford, FL
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Sanford Industrial Property with Fenced Yard
$699,900
1,740 SF

Sanford Industrial Property with Fenced Yard

2,695 SF industrial property with fenced outdoor storage.

414 W 9TH STREET, Sanford, FL 32771
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Sanford Office Unit For Sale
$450,000
2,037 SF

Sanford Office Unit For Sale

Office unit available for purchase in Sanford, Florida.

806 E 25TH STREET, Sanford, FL 32771
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Sanford Commercial/Mixed-Use Opportunity
$349,900
1,485 SF

Sanford Commercial/Mixed-Use Opportunity

Versatile commercial property near downtown Sanford with redevelopment potential.

420 MONROE ROAD, Sanford, FL 32771
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Sanford Commercial Space For Sale
$299,000
1,332 SF

Sanford Commercial Space For Sale

Versatile commercial space in Sanford, Florida with parking.

1013 Historic Goldsboro Blvd, Sanford, FL 32771
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Sanford Warehouse with Office/Showroom Space
$995,000
6,282 SF

Sanford Warehouse with Office/Showroom Space

6,282 SF building with warehouse and office/showroom space.

4366 North Ronald Reagan Blvd, Sanford, FL 32773
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New Sanford Professional/Medical Office Building
$995,000
0.08 Acres

New Sanford Professional/Medical Office Building

New construction professional/medical office building available for immediate occupancy.

1300 LEXINGTON GREEN LANE, Sanford, FL 32771
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Sanford Medical Office For Sale
$675,000
1,550 SF

Sanford Medical Office For Sale

Turnkey 1,550 SF medical office in Sanford, Florida.

2105 S PARK AVENUE, Sanford, FL 32771
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Downtown Sanford Mixed-Use Building
$1,495,000
4,930 SF

Downtown Sanford Mixed-Use Building

4,930 SF mixed-use building in Downtown Sanford, Florida.

203 E 3rd St, Sanford, FL 32771
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Sanford Historic District Office Building
$679,000
1,938 SF

Sanford Historic District Office Building

Charming Mediterranean-style office building in Sanford's Historic District.

720 S PARK AVENUE, Sanford, FL 32771
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Rehabbed Property with Redevelopment Potential
$249,900
882 SF

Rehabbed Property with Redevelopment Potential

Rehabbed commercial property, currently leased, with redevelopment potential.

2882 Sanford Ave, Sanford, FL 32773
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Sanford Warehouse with Showroom/Office
Contact for pricing
40,000 SF

Sanford Warehouse with Showroom/Office

40,000 SF warehouse with showroom and office space.

2650 Jewett Ln, Sanford, FL 32771
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Sanford, FL Office Properties & Spaces Investment Opportunities Market Analysis

Explore 28 office properties & spaces for sale in Sanford, FL, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 3,308,499 square feet of properties for sale, with an estimated market value of $84,587,899.

Sale prices for office spaces in Sanford, FL start at $70,000, averaging $494,666, and reaching up to $3,295,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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