Office Building

Port Saint Lucie, FL Office Buildings for Lease

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Fort Pierce, FL Jensen Beach, FL Stuart, FL Vero Beach, FL Palm City, FL Hobe Sound, FL Indiantown, FL
Freestanding Medical Office Space
Updated: Aug 19
Freestanding Medical Office Space

761 E Prima Vista Blvd, Port Saint Lucie, FL 34952

Contact for pricing
1,425 sqft 0.27 AC lot
1,425+/- SF freestanding professional or medical office building
11,761+/- SF lot with fenced backyard and tropical landscaping
Reception area, 3 private offices or treatment rooms, 2 restrooms, kitchen, storage, and flexible workspace
On‑site and covered parking with monument signage on E Prima Vista Boulevard
Terrazzo flooring, washer/dryer, and 220‑volt electrical service
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Well-Maintained Property For Sale
Updated: Nov 24, 2025
Well-Maintained Property For Sale

7430-7448 S Federal Hwy, Port Saint Lucie, FL

Contact for pricing
13,129 sqft 1.09 AC lot
Great short term upside potential
Great street visibility
Easy access
Well maintained property
Long term occupants
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Single-Story Office Building For Rent
Single-Story Office Building For Rent

120-128 SW Chamber Court, Port Saint Lucie, FL 34986

$22 SF/Yr

Single-story office building with immediate availability and hurricane impact glass.

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Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 3 Active listings in Port Saint Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Freestanding Live-Work Space
Freestanding Live-Work Space

Port St Lucie, FL 34952

$4,216/Mo
1,865 sqft 0.27 AC lot

Flexible office layout includes private rooms, reception, restrooms, kitchen, storage, and workspace.

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Freestanding Medical Office Building
Freestanding Medical Office Building

1215 S 25th Street S, Fort Pierce, FL 34947

$6,600/Mo
2,416 sqft

Configured with private rooms, reception, support areas, and three restrooms.

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Multi-Tenant Office Buildings
Multi-Tenant Office Buildings

805 Virginia Ave, Fort Pierce, FL 34982

$18 SF/Yr
27,000 sqft 2.55 AC lot

Single-story office buildings offer leasing options along Virginia Avenue.

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New Class A Office Building
New Class A Office Building

Port St Lucie, FL 34952

$23 SF/Yr

Newly constructed Class A commercial building available for rent.

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Port Saint Lucie, FL Office buildings Lease Rates & Market Statistics

Explore 3 Office buildings for lease in Port Saint Lucie, FL on Realmo, a commercial real estate exchange covering the Port Saint Lucie area. The current inventory totals 14,554 square feet of properties.

Office buildings lease rates in Port Saint Lucie range from $22 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $22 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $22 SF/Yr is 18% below the Florida state average of $26.70 SF/Yr.

Port Saint Lucie accounts for 30% of the 10 office buildings currently available across St. Lucie County, where nearby markets include Port St Lucie and Fort Pierce. Office buildings are one of the more limited space types in Port Saint Lucie, with just 3 listings currently available — a scarcity worth factoring into lease negotiations. Tenants comparing options may also consider Office Units (6 listings) and Medical Office Space (5 listings) elsewhere in the Port Saint Lucie market.

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