Port Saint Lucie, FL Office Units for Rent & Lease

Updated: Jul 16

Flexible Office Suite with Private Office

250-270 NW Peacock Blvd, Port Saint Lucie, FL 34986

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1,300 sqft

1,300 +/- SF commercial suite (Suite 104) at 270 NW Peacock Boulevard in St. Lucie West
Flexible layout with an open floor plan plus 1 private office and 1 restroom
Zoned CG (General Commercial) for professional offices, medical/wellness, retail, boutique fitness, and service uses
Convenient access to Interstate 95 and Florida's Turnpike
Just 2 minutes from Clover Park (New York Mets spring training home)

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Updated: Nov 25, 2025

Single-Story Office Building For Rent

120-128 SW Chamber Court, Port Saint Lucie, FL 34986

$22 SF/Yr

4,020 SF of immediately available space.
Benefit from all hurricane impact glass windows and doors.
Direct access to your suite.
Numerous restaurants and shops nearby.
Located east of I‑95, off of St. Lucie West Blvd.

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Port St. Lucie Office Space

155 SW Port St Lucie Blvd, Port Saint Lucie, FL

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2,500 sqft 1.63 AC lot

2,500 SF office space in a thriving commercial corridor.

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Port St. Lucie Office Space

7664 S US Hwy 1, Port Saint Lucie, FL

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3,753 sqft 1.67 AC lot

Versatile office space in a high-traffic Port St. Lucie location.

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Professional Office Space For Lease

550 SE Port St Lucie Blvd, Port Saint Lucie, FL

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700 sqft 0.75 AC lot

Two-story office building with recent renovations and ample parking.

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Office Space For Rent

1631 NW St Lucie West Blvd, Port Saint Lucie, FL

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1,629 sqft 1.07 AC lot

Office space available for lease in Port Saint Lucie, FL.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 6 Active listings in Port Saint Lucie, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Office Units for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Shared Medical Office Space

300 NW Bethany Dr #320, Port St Lucie, FL 34986

$3,000-$4,000/Mo

2,000 sqft

Existing exam rooms, a nurse station, and a spacious waiting area support patient-facing operations.

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Office Space Available For Rent

Fort Pierce, FL 34986

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2,750 sqft 1.50 AC lot

Office space available for rent in Port St. Lucie, FL.

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Modern Flex Office Warehouse Units

3801 Oleander Ave, Fort Pierce, FL 34982

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1,500 sqft

Six move-in-ready flex units each include a showroom/office, private bathroom, and warehouse storage area.

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Executive Office Suites

951 SW Country Club Dr, Port St Lucie, FL 34986

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195 sqft

Executive office suites for lease within a golf club building, with high-speed internet and shared conference room access.

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Similar Spaces for Sale in Port Saint Lucie, FL

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Leased Office Bays Bundle

1082 SW Bayshore Boulevard, Port Saint Lucie, FL 34983

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Two commercial office bays are sold together and currently leased under a term with renewal options.

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Port Saint Lucie, FL Office Units Lease Rates & Market Statistics

Explore 6 Office Units for lease in Port Saint Lucie, FL on Realmo, a commercial real estate exchange covering the Port Saint Lucie area. The current inventory totals 9,882 square feet of properties.

Office Units lease rates in Port Saint Lucie range from $22 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $22 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $22 SF/Yr is 38% below the Florida state average of $35.34 SF/Yr.

Port Saint Lucie accounts for 10% of the 62 office units currently available across St. Lucie County, where nearby markets include Fort Pierce and Port St Lucie. Office Units make up 75% of the 8 Office Spaces currently for lease in Port Saint Lucie, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Medical Office Space (5 listings) and Office buildings (3 listings) elsewhere in the Port Saint Lucie market.