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Lexington County, SC Mixed-use Properties for Sale

19 results
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Columbia Mixed-Use Investment Opportunity
$2,999,000
1.74 Acres

Columbia Mixed-Use Investment Opportunity

1332 Broad River Rd, Columbia, SC 29210

Operating gas station, retail bays, home, and duplex on 1.74 acres.

  • High‑visibility corner location on Broad River Road with multiple access points and generous parking.
  • Mixed‑use property featuring an operating gas station and convenience store, two retail bays, a single‑family home, and a duplex.
  • Strong daily traffic and proximity to the I‑26/I‑20/I‑126 interchange.
  • Two large, flexible storefronts suitable for retail, service, office, restaurant, or medical use.
  • Existing residential structures provide additional rental potential or future redevelopment options.
Updated: Feb 12
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Versatile Lexington Property with Updates
$400,000
1,808 SF

Versatile Lexington Property with Updates

104 Round Knob Rd, Lexington, SC 29072

Updated 1.13-acre property zoned for limited commercial use.

  • Zoned LC (Limited Commercial) offering live‑work flexibility and business potential on a 1.13‑acre lot.
  • Move‑in ready 1,808 sq. ft. space with new HVAC, roof, flooring, interior paint, and professional landscaping.
  • Prime location minutes from top‑rated schools, dining, shopping, and Lexington’s business hub, behind OneLife Fitness Northlake off Hwy 378.
  • Expansive lot with ample parking and room to expand or redesign.
  • Suitable for a wide range of residential or commercial uses (medical, consulting, real estate, child care, insurance, contracting, etc.).
Updated: Nov 28, 2025
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Devine Street Commercial Opportunity
$130,000
925 SF

Devine Street Commercial Opportunity

Prime commercial property with high visibility in desirable Columbia corridor.

4455 Devine St, Columbia, SC 29205
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Mixed-Use Property in Columbia, SC
$52,000
0.24 Acres

Mixed-Use Property in Columbia, SC

Mixed-use property suitable for commercial and residential use.

5430 N Main St, Columbia, SC 29203
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Leesville Commercial Land Investment
$1,300,000
10.56 Acres

Leesville Commercial Land Investment

10+ acres in Leesville, SC, ideal for commercial or mixed-use.

1153 West Hampton Rd, Leesville, SC 29070
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Downtown Columbia Mixed-Use Opportunity
$90,000
0.10 Acres

Downtown Columbia Mixed-Use Opportunity

Mixed-use lot in downtown Columbia near amenities and highways.

617 Richland St, Columbia, SC 29201
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Office/Retail Building with Warehouse Space
Contact for pricing

Office/Retail Building with Warehouse Space

Well-maintained office/retail building with warehouse space and convenient location.

115 Clark St, Chapin, SC 29036
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Retail/Flex Building in Downtown
Contact for pricing

Retail/Flex Building in Downtown

Multi-tenant building with retail, showroom, office, and warehouse space.

300 Huger St, Columbia, SC 29201
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Historic Vista Building with Parking
Contact for pricing
12,170 SF

Historic Vista Building with Parking

Historic mixed-use building in The Vista with parking lot.

925 Park St, Columbia, SC 29201
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Downtown Columbia Redevelopment Opportunity
Contact for pricing
21,434 SF

Downtown Columbia Redevelopment Opportunity

One-acre redevelopment site at a prominent downtown intersection.

1600 Bull St, Columbia, SC 29201
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Renovated Office and Living Space
Contact for pricing
4,138 SF

Renovated Office and Living Space

Two-story building with flexible floorplan near Downtown Columbia.

132 Stonemark Ln, Columbia, SC 29210
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West Columbia Mixed-Use Opportunity
$1,400,000
5,000 SF

West Columbia Mixed-Use Opportunity

Prime West Columbia location, redevelopment potential.

1621 Sunset Blvd, West Columbia, SC 29169
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Charleston Hwy Mixed-Use Investment
$800,000
9,200 SF

Charleston Hwy Mixed-Use Investment

West Columbia, SC: Value-Add Opportunity

1101 Charleston Hwy, West Columbia, SC 29169
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West Columbia Industrial Property
$210,000
1,500 SF

West Columbia Industrial Property

Versatile 1,500 SF flex space, ideal for auto repair.

407 Taylor St, West Columbia, SC 29169
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Lexington Office Building - Great Potential
$399,000
3,400 SF

Lexington Office Building - Great Potential

3400 sq ft office space, ideal for various uses.

109 Lisa Dr, Lexington, SC 29073
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Columbia Mixed-Use Investment
$1,200,000
6,750 SF

Columbia Mixed-Use Investment

High-Cap Rate Restaurant Property

1704 Bush River Rd, Columbia, SC 29210
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Lexington Commercial Land - 18 Acres
$2,599,000
18.00 Acres

Lexington Commercial Land - 18 Acres

High-traffic location, development potential.

1131 Lake Dr, Lexington, SC 29073
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Red Bank Commercial Development
$3,500,000
4.41 Acres

Red Bank Commercial Development

Lexington, SC Mixed-Use Opportunity

5506 Platt Springs Rd, Lexington, SC 29073
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Irmo, SC Commercial Land - 6 Acres
$1,250,000
6.00 Acres

Irmo, SC Commercial Land - 6 Acres

Prime 6-acre commercial lot, I-26 access.

0 Broad River Rd, Irmo, SC 29063
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 19 Active Listings in Lexington County, SC, we suggest to view alternatives - similar 61 Off-Market properties to explore as potential leads.

Explore Off-Market Properties in Lexington County, SC

Consider similar Off-Market properties in Lexington County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1621 Sunset Blvd

1621 Sunset Blvd

Day care centers • 5,000 SF
Value Estimation by Request
1621 Sunset Blvd, West Columbia, SC 29169
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112 Haygood Ave

112 Haygood Ave

MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,874 SF
Value Estimation by Request
112 Haygood Ave, Lexington, SC 29072-2669
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309 Lk Dr

309 Lk Dr

OFFICE/RESIDENTIAL (MIXED USE) • 1,590 SF
Value Estimation by Request
309 Lk Dr, Lexington, SC 29072-2801
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3738 Augusta Hwy

3738 Augusta Hwy

STORE/OFFICE (MIXED USE) • 1,920 SF
Value Estimation by Request
3738 Augusta Hwy, Gilbert, SC 29054-9669
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633 Meeting St

633 Meeting St

STORE/OFFICE (MIXED USE) • 12,258 SF
Value Estimation
$615,000
633 Meeting St, West Columbia, SC 29169-7536
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Lexington County, SC Mixed-Use Properties Investment Opportunities Market Analysis

Explore 80 mixed-use properties for sale in Lexington County, SC, showcased through 19 active listings on our real estate platform. These investment opportunities span a total of 4,711,076 square feet of properties for sale, with an estimated market value of $22,544,000.

Sale prices for multi use buildings in Lexington County, SC start at $52,000, averaging $644,114, and reaching up to $3,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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