Greenwood County, SC Mixed-use properties for sale

Versatile Commercial Building, Greenwood SC

$159,000

1,722 SF

Versatile Commercial Building, Greenwood SC

1601 E Cambridge Ave, Greenwood, SC 29646

Adaptable commercial building with high visibility and flexible build-out options.

High‑visibility corner location with strong road presence
Large, open interior with high ceilings and exposed framing, ideal for customization
Flexible build‑out options suitable for retail, light industrial, workshop, studio, storage, or office conversion
Generous lot space for parking, storage, or expansion
Durable block construction

Updated: Feb 3

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Historic Uptown Greenwood Commercial Property

$749,000

4,684 SF

Historic Uptown Greenwood Commercial Property

206 Main St, Greenwood, SC 29649

Versatile commercial space in a vibrant historic district with unique features.

Prime Location: Situated in the heart of Uptown Greenwood with high visibility and foot traffic.
Versatile Space: Just under 5,000 sqft with a flexible layout suitable for retail, office, or mixed‑use purposes. Includes seven private office suites, a shared kitchenette, and a large basement.
Historic Charm: Features original hardwood floors, ghost murals (including a vintage Coca‑Cola mural), and architectural details reflecting its 1917 origins.
Ample Parking: Benefits from an expansive city‑owned front lot providing abundant parking.
Turnkey Opportunity: Includes all remaining furnishings upstairs, making it ready for a new business/owner.

Updated: Sep 9, 2025

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$479,000

4,753 SF

Iconic Mixed-Use Property, Greenwood SC

Mixed-use property in vibrant Uptown Greenwood, ideal for live/work.

204 Main St, Greenwood, SC 29649

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Greenwood Commercial Corner Lot Opportunity

$174,000

0.54 Acres

Greenwood Commercial Corner Lot Opportunity

Prime commercial lot in Greenwood's active corridor, ideal for development.

441/443 Calhoun Ave, Greenwood, SC 29649

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$2,000,000

5.00 Acres

Lake Greenwood Development Opportunity

5-acre waterfront property zoned for residential or mixed-use development.

7125 Ninety Six Hwy, Ninety Six, SC 29666

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Lake Greenwood Waterfront Development Opportunity

$2,000,000

5.00 Acres

Lake Greenwood Waterfront Development Opportunity

5-acre waterfront property with development potential on Lake Greenwood.

7125 Ninety Six Hwy, Ninety Six, SC 29666

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Explore Off-Market Properties in Greenwood County, SC

Consider similar Off-Market properties in Greenwood County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1732 By-Pass 72

Mixed-use properties • 20,884 SF

Value Estimation by Request

1732 By-Pass 72, Greenwood, SC 29649

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2432-C Hwy 293rd E

STORE/OFFICE (MIXED USE) • 2,940 SF

Value Estimation by Request

2432-C Hwy 293rd E, Greenwood, SC 29649

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327 Main St, Unit 6

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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805 Montague Ave

STORE/OFFICE (MIXED USE) • 13,660 SF

Value Estimation

$1,645,000

805 Montague Ave, Greenwood, SC 29649-1471

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418 Main St

STORE/OFFICE (MIXED USE) • 5,190 SF

Value Estimation by Request

418 Main St, Greenwood, SC 29646-2756

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327 Main St, Unit 2

STORE/OFFICE (MIXED USE) • 661 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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327 Main St, Unit 5

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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1325 Montague Ave Ext

STORE/OFFICE (MIXED USE) • 3,640 SF

Value Estimation by Request

1325 Montague Ave Ext, Greenwood, SC 29649-9028

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106 Byp 225

STORE/OFFICE (MIXED USE) • 11,507 SF

Value Estimation

$1,170,000

106 Byp 225, Greenwood, SC 29646-1154

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104 Maxwell Ave

STORE/OFFICE (MIXED USE) • 70,979 SF

Value Estimation

$2,980,000

104 Maxwell Ave, Greenwood, SC 29646-2641

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327 Main St, Unit 7

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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730 Greenwood Ave

STORE/OFFICE (MIXED USE) • 2,146 SF

Value Estimation by Request

730 Greenwood Ave, Ware Shoals, SC 29692-1233

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327 Main St, Unit 3

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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601 Kitson St

STORE/OFFICE (MIXED USE) • 9,912 SF

Value Estimation by Request

601 Kitson St, Greenwood, SC 29646-2185

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1303 Montague Ave Ext

STORE/OFFICE (MIXED USE) • 5,824 SF

Value Estimation

$525,000

1303 Montague Ave Ext, Greenwood, SC 29649-9028

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327 Main St, Unit 4

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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328 Main St

STORE/OFFICE (MIXED USE) • 8,149 SF

Value Estimation

$540,000

328 Main St, Greenwood, SC 29646-2797

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422 Montague Ave

STORE/OFFICE (MIXED USE) • 9,864 SF

Value Estimation

$555,000

422 Montague Ave, Greenwood, SC 29649-1975

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300 Montague Ave

STORE/OFFICE (MIXED USE) • 11,766 SF

Value Estimation by Request

300 Montague Ave, Greenwood, SC 29649-1938

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202 Montague Ave

STORE/OFFICE (MIXED USE) • 1,831 SF

Value Estimation by Request

202 Montague Ave, Greenwood, SC 29649-1935

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327 Main St

STORE/OFFICE (MIXED USE) • 2,523 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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Greenwood County, SC Mixed-Use Properties Investment Opportunities Market Analysis

Explore 35 mixed-use properties for sale in Greenwood County, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 311,019 square feet of properties for sale, with an estimated market value of $8,323,000.

Sale prices for multi use buildings in Greenwood County, SC start at $159,000, averaging $924,777, and reaching up to $2,670,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Greenwood County, SC Mixed-use Properties for Sale

Versatile Commercial Building, Greenwood SC

Adaptable commercial building with high visibility and flexible build-out options.