Greene County, MO Mixed-use Properties for Sale

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Updated: Nov 21, 2025

Mixed-Use Property in Downtown Springfield

420 S Campbell Ave, Springfield, MO 65806

$1,100,000

12,577 sqft

Mixed‑use property with retail and residential income potential.
Prime Downtown Springfield location at the corner of Campbell and Pershing.
Two retail spaces: 1,500 SF and 4,200 SF. One retail space formerly used as a bar.
Three apartments: Two at 1,500 SF and one at 500 SF.
2,700 SF unfinished basement for storage.

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This listing looks promising.

Here's a quick look at some key insights for

420 S Campbell Ave, Springfield, MO 65806

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Est. Cap Rate

8.6%
Above avg (5.9%)
Est. NOI

$94K
Annual
Price @ 7% Cap

$1.34M
Above asking
Property Type

Commercial (General)
Built 1915

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Updated: Aug 21, 2025

Mixed-Use Building with On-Site Apartment

1213 E St Louis, Springfield, MO 65802

$449,900

0.38 AC lot

More than 5,955 SF mixed‑use building with main‑level office area and upstairs private apartment
Main level: approximately 2,655 SF with 10+ offices, reception, waiting room, work room, kitchen, storage, and dedicated kennels
Upstairs apartment: more than 1,980 SF with its own entrance, 2 bedrooms, and 2 full bathrooms
Traffic visibility near National Ave & St. Louis St: over 28,000 cars/day on National and 7,800 on St. Louis
Zoned INC with zoned central air and water available

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Historic Mixed-Use Building

504 W Commercial Street, Springfield, MO 65803

$285,000

0.19 AC lot

Multi-level property combines retail bays, loft areas, apartment rooms, and alley-served overhead doors.

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Historic Mixed-Use Building with Lofts

412 South Avenue, Springfield, MO 65806

$635,000

0.06 AC lot

Downtown Springfield mixed-use building with ground-floor retail and two loft apartments; fully occupied and zoned INC.

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Downtown Springfield Mixed-Use Building

220 S Campbell Ave, Springfield, MO 65806

$899,000

11,474 sqft 0.09 AC lot

Two-story mixed-use building in downtown Springfield with hospitality and office space.

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Free Standing Building on Kearney

521 W Kearney St, Springfield, MO 65803

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2,584 sqft

2,584 SF building on W Kearney in Springfield, Missouri.

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Downtown Mixed-Use Corner Property

420 S Campbell Ave, Springfield, MO 65806

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12,577 sqft

Mixed-use building with two retail spaces, three apartments, and a storage basement.

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Mixed-Use Building with Street Retail

300-308 West Commercial Street, Springfield, MO 65803

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17,230 sqft

Two-story mixed-use building with street-level commercial space and 11 loft-style residential units.

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Versatile Commercial Property Near Route 66

1646 E Saint Louis St, Springfield, MO 65806

$269,900

Light industrial/commercial property with office space and detached garage/shop.

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Versatile Commercial Property on Sunshine

5194 W Sunshine St, Springfield, MO 65802

$750,000

3.00 AC lot

3-acre property with office, barn, and residential home.

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Mixed-Use Office and Lofts

222 E Water St, Springfield, MO 65806

$1,400,000

Two-level office space with executive offices and conference room, plus two upper-level loft apartments.

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Historic Mixed-Use Building with STR License

214 E Commercial St, Springfield, MO 65803

$975,000

Three-story historic building rebuilt in 2012, offering a commercial storefront and two separately metered residential lofts with an active STR license.

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Downtown Springfield Mixed-Use Property

412 South Ave, Springfield, MO 65806

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4,100 sqft

Fully leased mixed-use property in Downtown Springfield with historic character.

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Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 13 Active listings in Greene County, MO, we suggest exploring several alternatives: similar 6 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Industrial Land With Multi-Street Access

S Farm Road 135, Springfield, MO 65807

$1,900,000

22.20 AC lot

M 2-zoned industrial land has access from Golden Ave, Glenn Ave, and Setting Sun Dr.

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Commercial Development Land with Utilities

4634 S Campbell Ave, Springfield, MO 65810

$2,175,000

4.00 AC lot

Commercial tract with 300+ feet of frontage, dual access, and utilities in place near major retail.

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Versatile Commercial Land Opportunity

W Farm Road 156, Springfield, MO 65802

$350,000

9.00 AC lot

9-acre commercial land in high-growth Springfield corridor.

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Commercial Land Near Tractor Supply

W Northview, Nixa, MO 65714

$1,000,000

5.74 AC lot

5.74-acre development land just off Highway 160 in Nixa with water available and adjacent to Tractor Supply.

Value Estimation by Request

4,878 sqft 0.03 AC lot

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Greene County, MO Mixed-Use Properties Market Trends and Statistics

Explore 19 mixed-use properties for sale in Greene County, MO, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 60,542 square feet of properties for sale, with an estimated market value of $6,763,800.

Sale prices for multi use buildings in Greene County, MO start at $269,900, averaging $751,533, and reaching up to $1,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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