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    Greene County, MO Mixed-use Properties for Sale

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    Found 44 mixed-use property listings for sale in Greene County, MO, averaging $119/sq ft. Use valuation data to compare deals faster.
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    Multi-Tenant Office and Retail Property
    Updated: Oct 2
    Multi-Tenant Office and Retail Property

    5601 S Campbell Avenue, Springfield, MO 65810

    $2,000,000
    2.00 AC lot
    Nearly 17,200 square feet on 2.0 acres
    10 suites: 9 leased and 1 available for an owner‑user
    South Campbell Avenue frontage and pole sign
    Three garage stalls with asphalt parking
    Roof installed in 2021; two HVAC systems added in 2023
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    Mixed-Use Building with Retail
    Updated: Oct 23
    Mixed-Use Building with Retail

    1341 E Kearney Street, Springfield, MO 65803

    $695,000
    0.73 AC lot
    10,000‑square‑foot building on a 0.73‑acre lot
    Upper level includes retail and office areas
    Basement has multiple large rooms and offices
    Six bathrooms
    Forced‑air, natural gas heating and electric cooling
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    Multi-Tenant Mixed-Use Property
    Multi-Tenant Mixed-Use Property

    5601 S Campbell Avenue, Springfield, MO 65810

    $2,550,000
    7.34 AC lot

    Nine suites are leased, with one additional suite available for occupancy.

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    Mixed-Use Building
    Mixed-Use Building

    1341 E Kearney St, Springfield, MO 65803

    $695,000
    10,000 sqft

    The property combines upper-level office and retail areas with a basement suited to a range of room configurations.

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    Mixed-Use Property with Commercial Building
    Mixed-Use Property with Commercial Building

    212 S Lafontaine Avenue, Springfield, MO 65806

    $225,000
    0.21 AC lot

    A remodeled residence and separate business space create a live-work configuration along Route 66.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    1111 E Walnut Street, Springfield, MO 65806

    $269,900
    0.20 AC lot

    Two-level layout combines office accommodations with an upper apartment and dedicated off-street parking.

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    Flex Property with Detached Outbuilding
    Flex Property with Detached Outbuilding

    2121 W College Street, Springfield, MO 65806

    $189,000
    0.20 AC lot

    GC-zoned property combines a renovated main structure, a separate two-story building, and grandfathered residential use.

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    Multi-Tenant Mixed-Use Property
    Multi-Tenant Mixed-Use Property

    5601 S Campbell Ave, Springfield, MO 65810

    $2,000,000
    17,196 sqft 2.00 AC lot

    Nine suites are leased, and one additional suite is available for an owner-user.

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    Mixed-Use Warehouse Complex
    Mixed-Use Warehouse Complex

    3001 E Pythian Street, Springfield, MO 65802

    $1,600,000
    2.00 AC lot

    GM-zoned property combines warehouse and office areas with a separate warehouse and indoor pool and fitness space.

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    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    214 E Commercial Street, Springfield, MO 65803

    $975,000
    0.05 AC lot

    Ground-floor commercial space and two lofts create separate occupancy and leasing options.

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    Remodeled Mixed-Use Property
    Remodeled Mixed-Use Property

    212 S Lafontaine Avenue, Springfield, MO 65806

    $225,000
    720 sqft

    Separate residential and commercial buildings provide distinct spaces for living and business operations.

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    Two-Building Restaurant Property
    Two-Building Restaurant Property

    111-115 W Main Street, Ash Grove, MO 65604

    $449,000
    0.10 AC lot

    Adjacent Main Street structures combine an operating restaurant layout with flexible space for retail, dining, or mixed-use redevelopment.

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    Furnished Mixed-Use Property with Lofts
    Furnished Mixed-Use Property with Lofts

    220 E Commercial Street, Springfield, MO 65803

    $3,445,000
    0.14 AC lot

    Combined restaurant and residential asset with an equipped kitchen and furnished loft residences.

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    Mixed-Use Property with Upstairs Apartment
    Mixed-Use Property with Upstairs Apartment

    1111 E Walnut Street, Springfield, MO 65806

    $269,900
    1,853 sqft

    The two-level layout combines office rooms below with a separate residential suite above.

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    Mixed-Use Property with Detached Garages
    Mixed-Use Property with Detached Garages

    1816 S Franklin Avenue, Springfield, MO 65807

    $585,000
    0.42 AC lot

    HC-zoned package combines commercial space with a neighboring residential home.

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    Mixed-Use Property with Arena
    Mixed-Use Property with Arena

    6323 W Farm Rd 156, Springfield, MO 65619

    $820,000
    3.33 AC lot

    The site combines a large arena building with a separate three-bedroom house.

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    Two-Building Restaurant Property
    Two-Building Restaurant Property

    111-115 W Main Street, Ash Grove, MO 65604

    $449,000
    8,335 sqft

    The main building has dining, bar, kitchen, patio, and upper-level loft space.

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    Historic Mixed-Use Redevelopment Property
    Historic Mixed-Use Redevelopment Property

    423 N Campbell Avenue, Springfield, MO 65806

    $2,250,000
    1.90 AC lot

    Historic buildings and a finished surface parking lot support multiple redevelopment concepts.

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    Mixed-Use Building with Loading Dock
    Mixed-Use Building with Loading Dock

    1430 W Kearney Street, Springfield, MO 65803

    $600,000
    6,065 sqft

    An occupied single-tenant property combines customer-facing retail space with a warehouse area and loading dock.

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    Mixed-Use Property with Upstairs Apartment
    Mixed-Use Property with Upstairs Apartment

    4114 S Lone Pine Avenue, Springfield, MO 65804

    $449,000
    0.13 AC lot

    Existing salon space and an upstairs apartment create a flexible two-level commercial configuration.

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    Mixed-Use Property with Warehouse
    Mixed-Use Property with Warehouse

    531 N Boonville Avenue, Springfield, MO 65806

    Contact for pricing
    10,296 sqft

    Office, retail, warehouse, and fenced outdoor storage are combined in a two-building property zoned CC—Center City.

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    Development Land Parcel
    Development Land Parcel

    E Kime Street, Willard, MO 65781

    $3,200,000
    118.60 AC lot

    Large development site across from the Willard Schools campus with access to Jackson St and Hwy 160.

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    Mixed-Use Property with Office-Retail Building
    Mixed-Use Property with Office-Retail Building

    1534 E Kearney Street, Springfield, MO 65803

    $950,000
    4,046 sqft 0.63 AC lot

    Eight one-bedroom units accompany the commercial building on a 0.63-acre parcel.

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    Mixed-Use Property with Storage
    Mixed-Use Property with Storage

    5194 W Sunshine, Springfield, MO 65802

    $750,000
    3.00 AC lot

    Multiple structures provide office, residential, garage, and barn/storage components across a commercial property.

    View details
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    Greene County, MO Mixed-Use Properties Market Trends and Statistics

    Explore 50 mixed-use properties for sale in Greene County, MO, showcased through 44 active listings on our real estate platform. These investment opportunities span a total of 271,391 square feet of properties for sale, with an estimated market value of $44,120,700.

    Sale prices for multi use buildings in Greene County, MO start at $189,000, averaging $1,103,017, and reaching up to $3,445,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Greene County Real Estate Agencies

    Realmo connects you with licensed Greene County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Greater Springfield, LLC
    300 E Sunshine Street, Suite A Springfield, MO 65807
    Phone: (417) 881-3061
    gsrealtors.com
    IMO Co., INC (Carol Jones Realtors)
    3600 S. National Ave. Springfield, MO 65807
    Phone: (417) 888-6612
    www.caroljones.com
    Southwest Realtors
    954 N. Oakwood Republic, MO 65738
    Phone: (417) 732-2195
    www.callsouthwest.com
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