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    Greene County, MO Mixed-use Properties for Sale

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    Multi-Tenant Mixed-Use Property
    Updated: Jul 20
    Multi-Tenant Mixed-Use Property

    5601 S Campbell Avenue, Springfield, MO 65810

    $2,550,000
    7.34 AC lot
    7.34‑acre mixed‑use property with nearly 17,200 square feet
    9 leased suites and 1 suite available for an owner‑user
    South Campbell Avenue frontage with pole sign
    New roof installed in 2021 and two new HVAC systems added in 2023
    Three garage stalls plus expansive asphalt parking
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    Historic Mixed-Use Property
    Updated: May 29
    Historic Mixed-Use Property

    1111 E Walnut Street, Springfield, MO 65806

    $269,900
    0.20 AC lot
    1894 construction with mixed‑use office and apartment configuration
    Main level includes reception area, 2 offices, kitchenette, and half bathroom
    Upper apartment has 2 bedrooms, full bathroom, kitchen, and loft living space
    Private parking lot accommodates 6‑8 cars
    Within walking distance of Missouri State University, shops, and restaurants
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    Flex Property with Rear Flex Room
    Flex Property with Rear Flex Room

    2121 W College Street, Springfield, MO 65806

    $200,000
    0.20 AC lot

    GC-zoned property combines office, storage, parking, and grandfathered residential use.

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    Historic Mixed-Use Building with STR License
    Historic Mixed-Use Building with STR License

    214 E Commercial St, Springfield, MO 65803

    $975,000
    6,023 sqft

    Three-story historic building rebuilt in 2012, offering a commercial storefront and two separately metered residential lofts with an active STR license.

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    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    214 E Commercial Street, Springfield, MO 65803

    $975,000
    0.05 AC lot

    Ground-floor commercial space and two lofts create separate occupancy and leasing options.

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    Two-Building Restaurant Property
    Two-Building Restaurant Property

    111-115 W Main Street, Ash Grove, MO 65604

    $449,000
    0.10 AC lot

    Adjacent Main Street structures combine an operating restaurant layout with flexible space for retail, dining, or mixed-use redevelopment.

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    Historic Mixed-Use Property with Showcase Front
    Historic Mixed-Use Property with Showcase Front

    117 W Main Street, Ash Grove, MO 65604

    $179,900
    0.09 AC lot

    1898 commercial building with storefront, apartment-style accommodations, patio, garage, and storage areas.

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    Mixed-Use Building with Street Retail
    Mixed-Use Building with Street Retail

    300-308 West Commercial Street, Springfield, MO 65803

    $2,800,000
    17,230 sqft

    Two-story mixed-use building with street-level commercial space and 11 loft-style residential units.

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    Furnished Mixed-Use Property with Lofts
    Furnished Mixed-Use Property with Lofts

    220 E Commercial Street, Springfield, MO 65803

    $3,445,000
    0.14 AC lot

    Combined restaurant and residential asset with an equipped kitchen and furnished loft residences.

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    Mixed-Use Property with Upstairs Apartment
    Mixed-Use Property with Upstairs Apartment

    4114 S Lone Pine Avenue, Springfield, MO 65804

    $495,000
    0.13 AC lot

    Existing salon space and an upstairs apartment create a flexible two-level commercial configuration.

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    Mixed-Use Building with Apartment
    Mixed-Use Building with Apartment

    4114 S Lone Pine Ave, Springfield, MO 65804

    $495,000
    2,840 sqft

    Two-level layout combines a salon with an upstairs apartment and abundant natural light.

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    Mixed-Use Property with Detached Garages
    Mixed-Use Property with Detached Garages

    1816 S Franklin Avenue, Springfield, MO 65807

    $585,000
    0.42 AC lot

    HC-zoned package combines commercial space with a neighboring residential home.

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    Historic Mixed-Use Redevelopment Property
    Historic Mixed-Use Redevelopment Property

    423 N Campbell Avenue, Springfield, MO 65806

    $2,250,000
    1.90 AC lot

    Historic buildings and a finished surface parking lot support multiple redevelopment concepts.

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    Free Standing Building on Kearney
    Free Standing Building on Kearney

    521 W Kearney St, Springfield, MO 65803

    $265,000
    2,584 sqft

    2,584 SF building on W Kearney in Springfield, Missouri.

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    Development Land Parcel
    Development Land Parcel

    E Kime Street, Willard, MO 65781

    $3,200,000
    118.60 AC lot

    Large development site across from the Willard Schools campus with access to Jackson St and Hwy 160.

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    Mixed-Use Shopping Center
    Mixed-Use Shopping Center

    1075-1137 E Commercial Street, Springfield, MO 65803

    $2,200,000
    3.20 AC lot

    Commercial property with retail units, leased and vacant space, parking, and water availability.

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    Mixed-Use Property in Downtown Springfield
    Mixed-Use Property in Downtown Springfield

    420 S Campbell Ave, Springfield, MO 65806

    $1,100,000
    12,577 sqft

    Mixed-use property with retail and apartments in Downtown Springfield.

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    Mixed-Use Property with Storage
    Mixed-Use Property with Storage

    5194 W Sunshine, Springfield, MO 65802

    $750,000
    3.00 AC lot

    Multiple structures provide office, residential, garage, and barn/storage components across a commercial property.

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    Mixed-Use Property with Office Warehouse
    Mixed-Use Property with Office Warehouse

    1908 N NATIONAL AVE, Springfield, MO 65803

    Contact for pricing
    1,698 sqft

    General Commercial property with office, warehouse, and residential remodeling potential.

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    Manufacturing-Zoned Property with Warehouse Use
    Manufacturing-Zoned Property with Warehouse Use

    5248 W Farm Road 156, Springfield, MO 65802

    $269,900
    1.00 AC lot

    Manufacturing-zoned property with a 4-bedroom home and options for light manufacturing or off-site storage.

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    Downtown Springfield Mixed-Use Building
    Downtown Springfield Mixed-Use Building

    220 S Campbell Ave, Springfield, MO 65806

    $899,000
    11,474 sqft 0.09 AC lot

    Two-story mixed-use building in downtown Springfield with hospitality and office space.

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    Historic Mixed-Use Property
    Historic Mixed-Use Property

    222 Park Central N, Springfield, MO 65806

    $649,000
    0.03 AC lot

    Ground-floor restaurant space is paired with two residential lofts.

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    Three-Story Religious Facility
    Three-Story Religious Facility

    500 South Avenue, Springfield, MO 65806

    Contact for pricing
    30,000 sqft

    Stone construction, a working elevator, and on-site parking define this three-floor institutional building.

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    Mixed-Use Office and Lofts
    Mixed-Use Office and Lofts

    222 E Water St, Springfield, MO 65806

    $1,400,000

    Two-level office space with executive offices and conference room, plus two upper-level loft apartments.

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    Greene County, MO Mixed-Use Properties Market Trends and Statistics

    Explore 32 mixed-use properties for sale in Greene County, MO, showcased through 26 active listings on our real estate platform. These investment opportunities span a total of 84,426 square feet of properties for sale, with an estimated market value of $27,421,600.

    Sale prices for multi use buildings in Greene County, MO start at $179,900, averaging $1,142,566, and reaching up to $3,445,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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