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    Middlesex County, MA Mixed-use Properties for Sale

    28 results
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    Newton Mixed-Use Development Opportunity
    $995,000
    2,852 SF

    Newton Mixed-Use Development Opportunity

    1100-1102 Beacon St, Newton, MA 02461

    Rare mixed-use property in prime Newton location, high visibility.

    • Rare stand‑alone mixed‑use building in Newton.
    • Prime central location with exceptional visibility and access.
    • Proximity to multiple Newton centers.
    • High commuter traffic area.
    • Phase 1 environmental assessment completed.
    Updated: Jan 1
    View details
    Mixed-Use Building Near UMASS Lowell
    $1,300,000
    7,178 SF

    Mixed-Use Building Near UMASS Lowell

    169-171 Salem St, Lowell, MA 01854

    Five-unit mixed-use building with retail space and residential units.

    • 5‑unit mixed‑use building with retail space and residential units.
    • First‑floor retail space includes a kitchen area, 2 walk‑in coolers, 1 walk‑in freezer, and pizza ovens.
    • Two updated 3‑bedroom apartments.
    • All units have separate utilities and washer/dryer hookups.
    • Includes business/Cote's market name, equipment, and inventory.
    Updated: Dec 8, 2025
    View details
    Lowell Mixed-Use Investment Opportunity
    $795,000
    3,774 SF

    Lowell Mixed-Use Investment Opportunity

    Mixed-use property with commercial space and residential unit in Lowell.

    525 Chelmsford St, Lowell, MA 01851
    View details
    Mixed-Use Property in Vibrant Location
    $1,849,999
    9,960 SF

    Mixed-Use Property in Vibrant Location

    Remodeled mixed-use property with residential units and commercial space.

    340 Main St, Everett, MA 02149
    View details
    Mixed-Use Building in Downtown Waltham
    $2,100,000

    Mixed-Use Building in Downtown Waltham

    Mixed-use commercial/residential building in downtown Waltham, great investment opportunity.

    605-607 Main St, Waltham, MA 02452
    View details
    Mixed-Use Portfolio in Newton
    $1,999,999
    4,500 SF

    Mixed-Use Portfolio in Newton

    Fully-tenanted mixed-use portfolio with income and expansion potential.

    262 Adams St, Newton, MA 02458
    View details
    Waltham Industrial Commercial Building
    $1,399,900
    4,687 SF

    Waltham Industrial Commercial Building

    4600 sq ft industrial building in downtown Waltham.

    25-29 Spring St, Waltham, MA 02451
    View details
    Mixed-Use Building Near Moody Street
    $2,399,000
    4,585 SF

    Mixed-Use Building Near Moody Street

    Mixed-use property with residential, rooming house, and salon spaces.

    55-57 Crescent St, Waltham, MA 02453
    View details
    Acton Mixed-Use Investment Opportunity
    $1,500,000
    5,637 SF

    Acton Mixed-Use Investment Opportunity

    Historic Landmark, 5,637 SF, High Visibility

    144 Great Rd, Acton, MA 01720
    View details
    Acton Commercial Property: 61 Great Road
    $1,125,000
    5,000 SF

    Acton Commercial Property: 61 Great Road

    Versatile Acton Commercial Space

    61 Great Rd, Acton, MA 01720
    View details
    Iconic Malden Square Building
    Contact for pricing
    24,000 SF

    Iconic Malden Square Building

    24,000 SF Mixed-Use Opportunity

    399 Main St, Malden, MA 02148
    View details
    Framingham Mixed-Use Investment
    $4,666,000

    Framingham Mixed-Use Investment

    10,240 SF Office/Retail, Strong Income

    665 Cochituate Rd, Framingham, MA 01701
    View details
    Somerville Retail Space Opportunity
    Contact for pricing
    1,670 SF

    Somerville Retail Space Opportunity

    Commercial space in mixed-use building with outdoor access.

    1060 Broadway, Somerville, MA 02144
    View details
    New Mixed-Use Asset in Somerville
    $6,700,000

    New Mixed-Use Asset in Somerville

    Newly constructed mixed-use property in Somerville's Union Square neighborhood.

    379 Somerville Ave, Somerville, MA 02143
    View details
    Mixed-Use Property Near Commuter Rail
    $1,530,000

    Mixed-Use Property Near Commuter Rail

    Mixed-use property with auto repair potential near commuter rail.

    12 Waverly St, Framingham, MA 01702
    View details
    Downtown Natick Mixed-Use Building
    Contact for pricing
    89,500 SF

    Downtown Natick Mixed-Use Building

    Street-level retail/restaurant space in a newly developed mixed-use building.

    45 East Central St, Natick, MA 01760
    View details
    Natick Center Redevelopment Opportunity
    $1,300,000

    Natick Center Redevelopment Opportunity

    Two-family house plus detached commercial/retail building in Natick Center.

    49 Summer St, Natick, MA 01760
    View details
    Mixed-Use Redevelopment Opportunity
    $1,900,000

    Mixed-Use Redevelopment Opportunity

    Mixed-use building with redevelopment potential in MBTA overlay district.

    540 Merrimack St, Lowell, MA 01854
    View details
    Mixed-Use Investment Property in Hudson
    $4,750,000

    Mixed-Use Investment Property in Hudson

    Mixed-use property with retail and apartment units in downtown Hudson.

    65 Main St, Hudson, MA 01749
    View details
    Downtown Natick Retail Opportunity
    Contact for pricing
    28,422 SF

    Downtown Natick Retail Opportunity

    Retail space in a newly developed mixed-use building.

    21 Summer St, Natick, MA 01760
    View details
    Mixed-Use Building Near Malden Center
    $2,690,000
    8,289 SF

    Mixed-Use Building Near Malden Center

    Multi-unit building with commercial and residential units near transportation.

    91 Medford St, Malden, MA 02148
    View details
    Mixed-Use Development Opportunity
    $3,100,000

    Mixed-Use Development Opportunity

    Three contiguous lots with mixed-use development potential.

    66-68-70 Powder Mill Rd, Maynard, MA 01754
    View details
    Mixed-Use Building in Prime Location
    $899,900

    Mixed-Use Building in Prime Location

    Mixed-use building with residential and office/retail spaces in Lowell.

    42 Branch St, Lowell, MA 01851
    View details
    Somerville Retail Space Opportunity
    Contact for pricing
    1,670 SF

    Somerville Retail Space Opportunity

    Commercial space in mixed-use building with public and private outdoor spaces.

    1060 Broadway St, Somerville, MA 02144
    View details

    Middlesex County, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2966 mixed-use properties for sale in Middlesex County, MA, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 41,149,853 square feet of properties for sale, with an estimated market value of $819,540,000.

    Prices for multi use buildings in Middlesex County, MA start at $50,000, averaging $839,692, and reaching up to $14,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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