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    Middlesex County, MA Mixed-use Properties for Sale

    33 results
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    Littleton Mixed-Use Commercial Opportunity
    $900,000
    3,000 SF

    Littleton Mixed-Use Commercial Opportunity

    474 Great Rd, Littleton, MA 01460

    Versatile mixed-use property in high-traffic location near major highway.

    • High‑traffic location across from "The Point" and near 495 access.
    • Zoned mixed‑use (residential and industrial).
    • Versatile space suitable for retail, office, or mixed‑use development.
    • Potential for redevelopment as a two‑family home.
    • Garage currently used as a business.
    Last Update: Aug 7
    View details
    Mixed-Use Building Near UMASS Lowell
    $1,300,000
    7,178 SF

    Mixed-Use Building Near UMASS Lowell

    167-171 Salem St, Lowell, MA 01854

    Five-unit mixed-use building with retail space and residential units.

    • Mixed‑use building featuring retail space with kitchen, coolers, freezer, and pizza ovens, plus residential units.
    • Includes established business (Cote's Market), equipment, and inventory.
    • Two updated 3‑bedroom apartments.
    • Convenient location near UMASS Lowell and amenities.
    • Separate utilities and washer/dryer hookups for all units.
    Last Update: Nov 17
    View details
    Newton Mixed-Use Investment Opportunity
    $995,000
    2,852 SF

    Newton Mixed-Use Investment Opportunity

    Centrally located mixed-use property in Newton, exceptional visibility and access.
    1100-1102 Beacon St, Newton, MA 02461
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    Mixed-Use Property in Vibrant Location
    $1,849,999
    9,960 SF

    Mixed-Use Property in Vibrant Location

    Remodeled mixed-use property with residential units and commercial space.
    340 Main St, Everett, MA 02149
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    Mixed-Use Building in Prime Location
    $1,139,000

    Mixed-Use Building in Prime Location

    Mixed-use building with residential and commercial units in Waltham.
    301 River St, Waltham, MA 02453
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    Mixed-Use Building in Downtown Waltham
    $2,100,000

    Mixed-Use Building in Downtown Waltham

    Mixed-use commercial/residential building in downtown Waltham, great investment opportunity.
    605-607 Main St, Waltham, MA 02452
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    Mixed-Use Portfolio in Newton
    $1,999,999
    4,500 SF

    Mixed-Use Portfolio in Newton

    Fully-tenanted mixed-use portfolio with income and expansion potential.
    262 Adams St, Newton, MA 02458
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    Waltham Industrial Commercial Building
    $1,399,900
    4,687 SF

    Waltham Industrial Commercial Building

    4600 sq ft industrial building in downtown Waltham.
    25-29 Spring St, Waltham, MA 02451
    View details
    Mixed-Use Building Near Moody Street
    $2,399,000
    4,585 SF

    Mixed-Use Building Near Moody Street

    Mixed-use property with residential, rooming house, and salon spaces.
    55-57 Crescent St, Waltham, MA 02453
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    Acton Mixed-Use Investment Opportunity
    $1,500,000
    5,637 SF

    Acton Mixed-Use Investment Opportunity

    Historic Landmark, 5,637 SF, High Visibility
    144 Great Rd, Acton, MA 01720
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    Acton Commercial Property: 61 Great Road
    $1,125,000
    5,000 SF

    Acton Commercial Property: 61 Great Road

    Versatile Acton Commercial Space
    61 Great Rd, Acton, MA 01720
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    Iconic Malden Square Building
    Contact for pricing
    24,000 SF

    Iconic Malden Square Building

    24,000 SF Mixed-Use Opportunity
    399 Main St, Malden, MA 02148
    View details
    Framingham Mixed-Use Investment
    $4,666,000

    Framingham Mixed-Use Investment

    10,240 SF Office/Retail, Strong Income
    665 Cochituate Rd, Framingham, MA 01701
    View details
    Mixed-Use Building Near Pailin Plaza
    $849,000

    Mixed-Use Building Near Pailin Plaza

    Mixed-use property with retail units and renovated apartment.
    717 Middlesex St, Lowell, MA 01851
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    Somerville Retail Space Opportunity
    Contact for pricing
    1,670 SF

    Somerville Retail Space Opportunity

    Commercial space in mixed-use building with outdoor access.
    1060 Broadway, Somerville, MA 02144
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    Mixed-Use Property Near Commuter Rail
    $1,530,000

    Mixed-Use Property Near Commuter Rail

    Mixed-use property with auto repair potential near commuter rail.
    12 Waverly St, Framingham, MA 01702
    View details
    New Mixed-Use Asset in Somerville
    $6,700,000

    New Mixed-Use Asset in Somerville

    Newly constructed mixed-use property in Somerville's Union Square neighborhood.
    379 Somerville Ave, Somerville, MA 02143
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    Downtown Natick Mixed-Use Building
    Contact for pricing
    89,500 SF

    Downtown Natick Mixed-Use Building

    Street-level retail/restaurant space in a newly developed mixed-use building.
    45 East Central St, Natick, MA 01760
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    Downtown Natick Retail Opportunity
    Contact for pricing
    28,422 SF

    Downtown Natick Retail Opportunity

    Retail space in a newly developed mixed-use building.
    21 Summer St, Natick, MA 01760
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    Renovated Mixed-Use Property in Stoneham
    $1,450,000

    Renovated Mixed-Use Property in Stoneham

    Mixed-use property with commercial space and residential apartment.
    44 Montvale Ave, Stoneham, MA 02180
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    Natick Center Redevelopment Opportunity
    $1,300,000

    Natick Center Redevelopment Opportunity

    Two-family house plus detached commercial/retail building in Natick Center.
    49 Summer St, Natick, MA 01760
    View details
    Mixed-Use Investment Property in Hudson
    $4,750,000

    Mixed-Use Investment Property in Hudson

    Mixed-use property with retail and apartment units in downtown Hudson.
    65 Main St, Hudson, MA 01749
    View details
    Mixed-Use Redevelopment Opportunity
    $1,900,000

    Mixed-Use Redevelopment Opportunity

    Mixed-use building with redevelopment potential in MBTA overlay district.
    540 Merrimack St, Lowell, MA 01854
    View details
    Arlington Mixed-Use Investment Opportunity
    $1,599,900

    Arlington Mixed-Use Investment Opportunity

    Mixed-use property with retail, office, and residential units for sale.
    1205 Massachusetts Ave, Arlington, MA 02476
    View details

    Middlesex County, MA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2971 mixed-use properties for sale in Middlesex County, MA, showcased through 33 active listings on our real estate platform. These investment opportunities span a total of 41,198,270 square feet of properties for sale, with an estimated market value of $829,595,000.

    Prices for multi use buildings in Middlesex County, MA start at $50,000, averaging $849,124, and reaching up to $14,030,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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