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Downtown Natick Mixed-Use Building
For Sale
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45 East Central Street, Natick, MA 01760

Street-level retail/restaurant space in a newly developed mixed-use building.

Property Size89,500 SF
Days on Market264

Property Features for 45 East Central Street

General Information

Standard status Active
Size 89,500 SF
Property subtype Mixed-Use (Residential & Retail)

Building Details

Building Size 89,500 SF
Year Built 2025

Properties For Sale

at 45 East Central Street Contact us

Unit 3

Size
850 SF
Type
Street Retail
Term
60 - 120 months
Contact us

Unit 5

Size
2,000 SF
Type
Street Retail
Term
60 - 120 months
Contact us
Listing Agency:
Listed By: Marilyn Santiago
Source: Naiglobal
Added: Nov 21, 2025 Changed: Aug 10 Last Checked: Aug 12 at 4:54AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Marilyn Santiago

Investment Insights

Based on property information with market context.

Located in downtown Natick, 45 East Central Street is a newly developed mixed-use building featuring 46 residential units and ground-level commercial space. The available space ranges from 1,500 to 6,000 square feet and is divisible. The property is situated in the heart of downtown Natick, surrounded by local retailers, restaurants, and municipal services, including Natick Town Hall and The Center for Arts in Natick (TCAN). TCAN is a cultural destination in the MetroWest region that draws nearly 30,000 visitors annually and hosts approximately 300 events each year. The location is near Natick Common and offers high visibility and accessibility, with proximity to dining, shopping, and entertainment options. The Natick Center MBTA Commuter Rail station is within walking distance, providing transportation to Boston and surrounding areas. Easy access to Route 135 and Route 9 enhances connectivity to regional business hubs. The property is suitable for restaurant with outdoor seating, retail, office, medical, education, and showroom uses.

Key Highlights

  • Prime downtown Natick location with high visibility and foot traffic.
  • Newly developed mixed‑use building with 46 residential units providing built‑in customer base.
  • Flexible space options available from 1,500 to 6,000± square feet, suitable for various uses.

Property Analytics

Current Use

Natick Family Eye ... Physician Frank E. Miller, ... Physician

Suggested Use

Top Pick Pharmacy Bakery Garden Center Grocery & Convenience Store Locksmith Food Market

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Location Intelligence

Trade Area within ½ mile

1,167
Businesses Nearby

Demographics for 01760, MA

36,659
Population
15,838
Households
2.3
Avg Household Size
42
Median Age
69%
College-Educated
98%
High-School Grad
14.8 sq mi
ZIP Area
2,477
Density / Sq Mi
$134,644
Median Household Income
$77,632
Median Earnings
$2,061
Median Rent
$740,700
Median Home Value

Market

Vacancy Rate% for Retail in Northeast region

6% 2019
7.1% 2020
6.5% 2021
6% 2022
5.7% 2023
5.6% 2024
6% 2025
Rey
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Frequently Asked Questions

What type of property is this?
Mixed-use property - Street-level retail/restaurant space in a newly developed mixed-use building.
Where is this mixed-use property located?
The property is located at 45 East Central Street Natick, MA.
What are key features of this property?
This property features: Prime downtown Natick location with high visibility and foot traffic.; Newly developed mixed‑use building with 46 residential units providing built‑in customer base.; Flexible space options available from 1,500 to 6,000± square feet, suitable for various uses.
More about this property
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