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    Columbia, SC Medical Office Space for Sale

    28 results
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    Medical Office Building For Sale
    $695,000
    4,900 SF

    Medical Office Building For Sale

    110 Atrium Way, Columbia, SC 29223

    4,900 SF medical office building with significant plumbing infrastructure.

    • ±4,900 SF medical office building with significant plumbing infrastructure.
    • Features eight (8) total exam rooms, including six with plumbing.
    • Located less than 1 mile from I‑77 with access along Two Notch Road and Atrium Way.
    • Includes X‑Ray and Two (2) Labs.
    • 33 surface parking spaces available.
    Updated: Nov 26, 2025
    View details
    Freestanding Medical Office Investment
    $1,250,000
    3,200 SF

    Freestanding Medical Office Investment

    131 Wildewood Park Drive, Columbia, SC 29223

    Freestanding medical office building for sale in Northeast Columbia.

    • Single tenant medical NNN investment offering
    • ±3,200 sf freestanding medical office building
    • Located off Two Notch Road near Sparkleberry Lane in Northeast Columbia
    • 22 surface parking spaces are available
    • Less than 4 miles from I‑20 and I‑77
    Updated: Mar 6
    View details
    High-Visibility Business/Office Center For Sale
    $2,250,000
    15,593 SF

    High-Visibility Business/Office Center For Sale

    Office/retail building with high visibility and customer parking.

    7358 Garners Ferry, Columbia, SC 29209
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    Downtown Office Condos For Sale
    $975,000
    5,528 SF

    Downtown Office Condos For Sale

    Four office condos totaling 5,528 SF in downtown Columbia.

    2757 Laurel St, Columbia, SC
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    Columbia Investment Property For Sale
    $1,798,000
    6,104 SF

    Columbia Investment Property For Sale

    Investment opportunity with a publicly traded tenant in Columbia, SC.

    1840 Pineview Dr, Columbia, SC
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    Freestanding Office Building For Sale
    Contact for pricing
    4,200 SF

    Freestanding Office Building For Sale

    4,200 SF office building for sale or lease.

    2901 Millwood Ave., Columbia, SC 29205
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    Downtown Columbia Office Building For Sale
    $3,000,000
    45,500 SF

    Downtown Columbia Office Building For Sale

    25,000 SF office building in downtown Columbia.

    950 Taylor St, Columbia, SC 29201
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    Medical Office Building For Sale
    $1,850,000
    14,442 SF

    Medical Office Building For Sale

    Medical office building with ample parking near medical campuses.

    1701 Saint Julian Pl, Columbia, SC
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    Versatile Commercial Property Near Columbia
    $399,000
    136,778 SF

    Versatile Commercial Property Near Columbia

    3.16 acres with 3,000+ sqft building, multiple operational possibilities.

    1510 Canal Dr, Columbia, SC 29210
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    Office/Medical Building Near Interchange
    $262,350
    2,915 SF

    Office/Medical Building Near Interchange

    2,915 SF office/medical building with ample parking for sale.

    392 St. Andrews Road, Columbia, SC 29210
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    Medical/Office Space in Forest Acres
    $1,850,000
    14,442 SF

    Medical/Office Space in Forest Acres

    Medical/office space available for sale or lease in Columbia.

    1701 St. Julian Place, Columbia, SC 29204
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    Turn-Key Medical Office in Columbia
    $3,150,000
    9,875 SF

    Turn-Key Medical Office in Columbia

    Class A medical office in NE Columbia with flexible layout.

    229 Longtown Rd, Columbia, SC
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    Columbia Office/Medical Building For Sale
    $3,000,000
    25,000 SF

    Columbia Office/Medical Building For Sale

    Office or medical building with flexible floorplates in Columbia.

    1527 Park St, Columbia, SC
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    Medical Office Condo Near Prisma
    $1,980,000
    22,263 SF

    Medical Office Condo Near Prisma

    Class A medical office condo for sale or lease.

    2113 Adams Grove Rd., Columbia, SC 29203
    View details
    Medical Office in Forest Acres
    Contact for pricing
    12,395 SF

    Medical Office in Forest Acres

    12,395 SF medical office space for sale or lease.

    1706 St. Julian Place, Columbia, SC 29204
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    Medical Office Near Medical Campuses
    Contact for pricing
    12,395 SF

    Medical Office Near Medical Campuses

    Medical office building with ample parking near medical facilities.

    1706 St Julian Pl, Columbia, SC
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    Medical Office on St. Andrews
    $230,000
    1,650 SF

    Medical Office on St. Andrews

    Medical office building with high visibility and accessibility.

    6148 Saint Andrews Rd, Columbia, SC
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    Former Dental Clinic For Rent
    $291,500
    2,915 SF

    Former Dental Clinic For Rent

    2,915 SF former dental clinic available for rent.

    392 Saint Andrews Rd, Columbia, SC
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    Dental Office in Columbia Corridor
    $1,995,000
    4,325 SF

    Dental Office in Columbia Corridor

    Well-maintained dental office in the SE Columbia corridor.

    741 Greenlawn Dr, Columbia, SC
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    High-Traffic Location Business/Office Center
    $2,250,000
    15,593 SF

    High-Traffic Location Business/Office Center

    Business/Office center with 41 suites in high-traffic location.

    7358 Garners Ferry, Columbia, SC 29209
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    Class A Medical Office Building
    $4,800,000
    20,000 SF

    Class A Medical Office Building

    Medical office building for sale in Northeast Columbia, SC.

    710 Rabon Rd, Columbia, SC 29203
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    Class A Medical Office Condo
    $1,980,000
    11,131 SF

    Class A Medical Office Condo

    Class A medical office condo for sale or lease.

    2113 Adams Grove, Columbia, SC
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    Medical Office Building For Sale
    $1,850,000
    14,442 SF

    Medical Office Building For Sale

    Medical office building for sale or lease in Forest Acres.

    1701 St Julian Pl, Columbia, SC 29204
    View details
    Turnkey Dental Office For Sale
    $1,995,000
    4,325 SF

    Turnkey Dental Office For Sale

    Dental office for sale in Southeast Columbia near Garners Ferry.

    741 Greenlawn Dr, Columbia, SC 29209
    View details

    Columbia, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 28 medical office space for sale in Columbia, SC, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 524,500 square feet of properties for sale, with an estimated market value of $12,790,000.

    Sale prices for medical spaces in Columbia, SC start at $100,000, averaging $983,846, and reaching up to $3,350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Medical Office Space for Sale Near Columbia, SC

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    Most Searched ZIP Codes in Columbia, SC

    • 29203
    • 29209
    • 29204
    • 29210
    • 29223
    • 29201
    • 29205

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