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Spartanburg, SC Medical Office Space for Sale

6 results
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Commercial Property Near Major Hospital
$275,000

Commercial Property Near Major Hospital

681 Chesnee Highway Ext, Spartanburg, SC 29303

Strategically located commercial property suited for medical or professional services.

  • Owner financing available.
  • Strategically located commercial property with substantial car traffic and visibility.
  • Ideally suited for a medical office or professional service near a major hospital.
  • Ample parking for employees and clients.
  • Essential amenities: kitchen, bathroom, and laundry facilities.
Updated: Sep 18, 2025
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Spartanburg Office Building For Sale
$1,810,000

Spartanburg Office Building For Sale

130 Dillon Dr, Spartanburg, SC 29307

7,200 SF office building near Spartanburg Medical District.

  • Prime location in Spartanburg, SC with excellent visibility.
  • Investment opportunity with a multi‑tenant building.
  • ±4,015 SF available, with ±3,185 SF already leased to Ortho Sport & Spine Physicians.
  • Close proximity to Spartanburg Medical District and other healthcare providers.
  • Ideal for primary care or specialty practices.
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Spartanburg Medical Office Building
Contact for pricing
11,058 SF

Spartanburg Medical Office Building

11,058 SF medical building; strong tenant base.

480 Floyd Rd, Spartanburg, SC 29307
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Medical Office Space Available
Contact for pricing
4,645 SF

Medical Office Space Available

4,645 SF medical office space for lease.

1241 Boiling Springs Rd, Spartanburg, SC 29303
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Spartanburg Medical/Office Building For Sale
Contact for pricing
6,440 SF

Spartanburg Medical/Office Building For Sale

9,594 SF medical/office building near downtown Spartanburg.

1770 Skylyn Dr, Spartanburg, SC 29307
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Professional Office/Medical Pads For Sale
Contact for pricing
3,500 SF

Professional Office/Medical Pads For Sale

Two office/medical pads with utilities, parking, and infrastructure included.

108 Burton St, Spartanburg, SC 29301
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Based on your search, we've compiled 179 Potential Opportunities for your consideration. Besides 6 Active listings in Spartanburg, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 169 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Greenville Medical Office Building
$500,000
1.17 Acres

Greenville Medical Office Building

9,000 SF Office/Lab, $500K

35 Brookfield Oaks Dr, Greenville, SC 29607
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Medical Office Building For Sale
Contact for pricing
7,397 SF

Medical Office Building For Sale

Two-story, ±7,397 SF medical office building suited for owner-occupant.

300 Regent Park Ct, Greenville, SC 29607
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Professional Office Building in Forest City
Contact for pricing

Professional Office Building in Forest City

Single-story brick building ideal for medical or dental use.

492 W Main St, Forest City, NC 28043
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Commercial Lot in Forest City
$75,000
0.56 Acres

Commercial Lot in Forest City

Ideal location for medical office with utilities available.

Withrow Rd, Forest City, NC 28043
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Explore Off-Market Properties in Spartanburg, SC

Consider similar Off-Market properties in Spartanburg, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

272 Cedar Spgs Rd

272 Cedar Spgs Rd

MEDICAL BUILDING • 5,432 SF
Value Estimation
$735,000
272 Cedar Spgs Rd, Spartanburg, SC 29302-4643
View details
1396 Boiling Spgs Rd

1396 Boiling Spgs Rd

MEDICAL BUILDING • 8,000 SF
Value Estimation
$935,000
1396 Boiling Spgs Rd, Spartanburg, SC 29303-2273
View details
1327 Old Charlotte Rd

1327 Old Charlotte Rd

MEDICAL BUILDING • 3,674 SF
Value Estimation
$530,000
1327 Old Charlotte Rd, Spartanburg, SC 29307
View details
456 Patillo Ct

456 Patillo Ct

MEDICAL BUILDING • 2,250 SF
Value Estimation by Request
456 Patillo Ct, Spartanburg, SC 29302-2612
View details
322 Pne St

322 Pne St

MEDICAL BUILDING • 7,951 SF
Value Estimation
$1,005,000
322 Pne St, Spartanburg, SC 29302-1631
View details
127 Southport Rd

127 Southport Rd

MEDICAL BUILDING • 2,300 SF
Value Estimation by Request
127 Southport Rd, Spartanburg, SC 29306-3815
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441 Church St

441 Church St

MEDICAL BUILDING • 2,820 SF
Value Estimation by Request
441 Church St, Spartanburg, SC 29306-5233
View details
271 Pne St

271 Pne St

MEDICAL BUILDING • 2,898 SF
Value Estimation by Request
271 Pne St, Spartanburg, SC 29302-2626
View details
383 Pne St

383 Pne St

MEDICAL BUILDING • 6,384 SF
Value Estimation
$760,000
383 Pne St, Spartanburg, SC 29302-2650
View details
1330 Boiling Spgs Rd Ste, Unit 2800

1330 Boiling Spgs Rd Ste, Unit 2800

MEDICAL BUILDING • 3,530 SF
Value Estimation by Request
1330 Boiling Spgs Rd Ste, Spartanburg, SC 29303-4216
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155 Dillon Dr

155 Dillon Dr

MEDICAL BUILDING • 5,248 SF
Value Estimation by Request
155 Dillon Dr, Spartanburg, SC 29307-1017
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122 Dillon Dr

122 Dillon Dr

MEDICAL BUILDING • 3,951 SF
Value Estimation by Request
122 Dillon Dr, Spartanburg, SC 29307-1018
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151 Dillon Dr

151 Dillon Dr

MEDICAL BUILDING • 2,280 SF
Value Estimation by Request
151 Dillon Dr, Spartanburg, SC 29307-1017
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480 Floyd Rd

480 Floyd Rd

MEDICAL BUILDING • 11,178 SF
Value Estimation
$1,340,000
480 Floyd Rd, Spartanburg, SC 29307-1518
View details
203 Fremont Ave

203 Fremont Ave

MEDICAL BUILDING • 9,274 SF
Value Estimation
$890,000
203 Fremont Ave, Spartanburg, SC 29303-2932
View details
2995 Reidville Rd

2995 Reidville Rd

MEDICAL BUILDING • 37,898 SF
Value Estimation
$4,535,000
2995 Reidville Rd, Spartanburg, SC 29301-5628
View details
1650 Skylyn Dr

1650 Skylyn Dr

MEDICAL BUILDING • 112,735 SF
Value Estimation
$10,710,000
1650 Skylyn Dr, Spartanburg, SC 29307-1047
View details
1330 Boiling Spgs Rd Ste, Unit 1100

1330 Boiling Spgs Rd Ste, Unit 1100

MEDICAL BUILDING • 1,972 SF
Value Estimation by Request
1330 Boiling Spgs Rd Ste, Spartanburg, SC 29303-4202
View details

Spartanburg, SC Medical Office Space Investment Opportunities Market Analysis

Explore 175 medical office space for sale in Spartanburg, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 9,312,642 square feet of properties for sale, with an estimated market value of $87,495,000.

Sale prices for medical spaces in Spartanburg, SC start at $75,000, averaging $1,093,687, and reaching up to $10,190,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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