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Bluffton, SC Medical Offices for Sale

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Bluffton Commercial Space For Sale
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231,304 SF

Bluffton Commercial Space For Sale

3 Hampton Lake Dr, Bluffton, SC 29910

Modern retail, office, and medical space near Hampton Lake entrance.

  • Prime location at the entrance of Hampton Lake with Bluffton Parkway frontage.
  • Lighted intersection access for high visibility and easy access.
  • Proximity to Buckwalter Place with shops, restaurants, hospitals, and everyday amenities.
  • Mix of retail, high‑end office, and medical office space.
  • Commercial condos available for sale (select few).
Updated: Aug 13, 2025
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Bluffton Medical Office Building
$2,995,000
6,808 SF

Bluffton Medical Office Building

14 Oak Forest Rd, Bluffton, SC 29910

Prime Medical Office, Bluffton SC

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Bluffton Office/Medical Building For Sale
Contact for pricing
17,525 SF

Bluffton Office/Medical Building For Sale

Class A office/medical building fronting Highway 278 in Bluffton.

5 Buck Island Rd, Bluffton, SC 29910
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Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 3 Active listings in Bluffton, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Stand Alone Medical Office Building
Contact for pricing
3,600 SF

Stand Alone Medical Office Building

Stand-alone medical building on Hilton Head Island, ready for occupancy.

4101 Main St, Hilton Head Island, SC 29926
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Medical Office Suite Near Hospital
Contact for pricing
1,500 SF

Medical Office Suite Near Hospital

Ground floor medical office suite available near Hilton Head Hospital.

23 Main St, Hilton Head Island, SC 29926
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Office/Medical Suite Near Port Royal
Contact for pricing
3,224 SF

Office/Medical Suite Near Port Royal

Office/medical suite for lease near Port Royal in Beaufort, SC.

1264 Ribaut Rd, Beaufort, SC 29902
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Beaufort Medical Office Building
$575,000
5,480 SF

Beaufort Medical Office Building

Prime Beaufort location, 5,480 SF, $575,000

2749 Boundary St, Beaufort, SC 29906
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Explore Off-Market Properties in Bluffton, SC

Consider similar Off-Market properties in Bluffton, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

Wy New Riverside Vlg

Wy New Riverside Vlg

Medical offices • 13,200 SF
Value Estimation by Request
Wy New Riverside Vlg, Bluffton, SC 29910
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14 Oak Forest Rd

14 Oak Forest Rd

Medical offices • 6,808 SF
Value Estimation by Request
14 Oak Forest Rd, Bluffton, SC 29910
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164 Bluffton Rd

164 Bluffton Rd

MEDICAL BUILDING • 3,230 SF
Value Estimation by Request
164 Bluffton Rd, Bluffton, SC 29910-6248
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10 Oak Frst Rd

10 Oak Frst Rd

MEDICAL BUILDING • 9,926 SF
Value Estimation by Request
10 Oak Frst Rd, Bluffton, SC 29910-4973
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64 Bluffton Rd

64 Bluffton Rd

MEDICAL BUILDING • 6,025 SF
Value Estimation
$3,460,000
64 Bluffton Rd, Bluffton, SC 29910-7621
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168 Bluffton Rd

168 Bluffton Rd

MEDICAL BUILDING • 2,376 SF
Value Estimation by Request
168 Bluffton Rd, Bluffton, SC 29910-6248
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48 Okatie Ctr S Blvd

48 Okatie Ctr S Blvd

MEDICAL BUILDING • 48,862 SF
Value Estimation by Request
48 Okatie Ctr S Blvd, Bluffton, SC 29909
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81 Baylor Dr

81 Baylor Dr

MEDICAL BUILDING • 61,102 SF
Value Estimation by Request
81 Baylor Dr, Bluffton, SC 29910
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Bluffton Pkwy

Bluffton Pkwy

MEDICAL BUILDING • 6,337 SF
Value Estimation by Request
Bluffton Pkwy, Bluffton, SC 29910
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101 Okatie Ctr S Blvd

101 Okatie Ctr S Blvd

MEDICAL BUILDING • 6,565 SF
Value Estimation by Request
101 Okatie Ctr S Blvd, Bluffton, SC 29909-7547
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1 Burnt Church Rd

1 Burnt Church Rd

MEDICAL BUILDING • 5,577 SF
Value Estimation by Request
1 Burnt Church Rd, Bluffton, SC 29910-6405
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3 Plantation Park Dr

3 Plantation Park Dr

MEDICAL BUILDING • 4,120 SF
Value Estimation
$1,435,000
3 Plantation Park Dr, Bluffton, SC 29910-6035
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162 Bluffton Rd

162 Bluffton Rd

MEDICAL BUILDING • 5,040 SF
Value Estimation by Request
162 Bluffton Rd, Bluffton, SC 29910-6340
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4818 Bluffton Pkwy

4818 Bluffton Pkwy

MEDICAL BUILDING • 8,664 SF
Value Estimation by Request
4818 Bluffton Pkwy, Bluffton, SC 29910-4602
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7 Palmetto Way

7 Palmetto Way

MEDICAL BUILDING • 5,490 SF
Value Estimation by Request
7 Palmetto Way, Bluffton, SC 29910-9696
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Bluffton, SC 29910

Bluffton, SC 29910

MEDICAL BUILDING • 3,648 SF
Value Estimation by Request
Bluffton, SC 29910
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100 Buckwalter Pl Blvd

100 Buckwalter Pl Blvd

MEDICAL BUILDING • 40,847 SF
Value Estimation
$12,880,000
100 Buckwalter Pl Blvd, Bluffton, SC 29910-5022
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35 Pondberry St

35 Pondberry St

MEDICAL BUILDING • 4,260 SF
Value Estimation
$3,040,000
35 Pondberry St, Bluffton, SC 29910-9724
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110 Buckwalter Pl Blvd

110 Buckwalter Pl Blvd

MEDICAL BUILDING • 3,828 SF
Value Estimation by Request
110 Buckwalter Pl Blvd, Bluffton, SC 29910-5154
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Buckwalter Pkwy

Buckwalter Pkwy

MEDICAL BUILDING • 2,992 SF
Value Estimation by Request
Buckwalter Pkwy, Bluffton, SC 29910
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31 Innovation Dr

31 Innovation Dr

MEDICAL BUILDING • 6,320 SF
Value Estimation by Request
31 Innovation Dr, Bluffton, SC 29910-5159
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Bluffton, SC Medical Offices Investment Opportunities Market Analysis

Explore 27 medical offices for sale in Bluffton, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 553,734 square feet of properties for sale, with an estimated market value of $28,880,000.

Prices for medical spaces in Bluffton, SC start at $250,000, averaging $2,888,000, and reaching up to $13,570,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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