Medical Premises

York, PA Medical Office Space for Sale

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Two-Story Office/Flex Building
Updated: May 20
Two-Story Office/Flex Building

221 E Princess St, York, PA 17403

$325,000
5,250 sqft 0.19 AC lot
Vacant two‑story commercial building with 5,250 SF total in a two‑unit office/flex layout
8,466 SF lot at 221‑225 E. Princess Street with dedicated on‑site parking lot
High‑visibility corner location on E. Princess Street
Two suites on 1st and 2nd floors in a flexible office/flex configuration
Zoned for office/flex commercial use (vacant with immediate possession at closing)
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221 E Princess St, York, PA

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Office Condominium Suite
Updated: Jul 6
Office Condominium Suite

1600 6th Ave, Suite 101/1D, York, PA 17403

$957,500
6,871 sqft
6th Avenue Professional Center is a 68,788 SF office condominium complex built in 2004
Suite 101/1D is located within a raised‑floor office condominium complex
Features include patient drop‑off area and secure entrances
Common area amenities include common area restrooms and family waiting areas
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Medical Facility in Park-Like Setting
Medical Facility in Park-Like Setting

50 Wyntre Brooke Dr, York, PA

$647,000
5,016 sqft 0.66 AC lot

Two-story medical facility with outdoor space and tenant potential.

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Medical Office Condominium Units
Medical Office Condominium Units

1776 S Queen St, York, PA 17403

$1,511,746
7,830 sqft

Condo units leased to OSS Orthopedic Hospital until 2029.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 4 Active listings in York, PA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 68 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Medical Office Space For Sale
Medical Office Space For Sale

864 Broadway, Hanover, PA 17331

$949,000
12,491 sqft

12,491 SqFt medical office space available for purchase.

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Turnkey All-Brick Commercial Building
Turnkey All-Brick Commercial Building

735 S PLEASANT Avenue, Dallastown, PA 17313

$425,000
0.45 AC lot

Turnkey all-brick building with ample parking, positioned near I-83 and the PA/MD line for flexible commercial use.

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Turn-Key Building in Prime Location
Turn-Key Building in Prime Location

735 S Pleasant Ave, Dallastown, PA 17313

$425,000
0.45 AC lot

All-brick building with ample parking and convenient highway access.

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Medical Office Condo For Sale
Medical Office Condo For Sale

250 Fame Ave, Hanover, PA 17331

$1,250,000
10,000 sqft

Turn-key medical office suite in Hillside Medical Center.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land in Mechanicsburg, PA
Commercial Land in Mechanicsburg, PA

S YORK Street, Mechanicsburg, PA 17055

$2,050,000
39.99 AC lot

Commercial land available within new Charter Homes development.

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Prime Commercial Land Opportunity
Prime Commercial Land Opportunity

4041 Linglestown Road, Harrisburg, PA 17112

$495,000
2.00 AC lot

2-acre commercial land with high visibility in Harrisburg.

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Shovel-Ready Medical Commercial Land
Shovel-Ready Medical Commercial Land

RED HORSE RD AND MATTHEW LANE - 4.63 ACRES, Pottsville, PA 17901

$449,000
4.67 AC lot

4.6-acre site subdivided into three approved lots with public water and sewer, utilities, and stormwater controls in place.

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Shovel-Ready Medical Commercial Land
Shovel-Ready Medical Commercial Land

RED HORSE RD AND MATTHEW LANE - 1.543 ACRE PARCEL, Pottsville, PA 17901

$179,000
1.55 AC lot

Commercial/medical-zoned land with public water and sewer, utilities on site, and recorded subdivision approvals.

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Off-Market Properties in York, PA

Consider similar Off-Market properties in York, PA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

3218 Market St
MEDICAL BUILDING

3218 Market St, York, PA 17402-2506

Value Estimation by Request
4,612 sqft 0.33 AC lot
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1943 Security Dr
MEDICAL BUILDING

1943 Security Dr, York, PA 17402-4728

Value Estimation by Request
2,034 sqft 0.23 AC lot
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1935 Security Dr
MEDICAL BUILDING

1935 Security Dr, York, PA 17402-4728

Value Estimation by Request
2,584 sqft 0.52 AC lot
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1689 Kenneth Rd
MEDICAL BUILDING

1689 Kenneth Rd, York, PA 17408-2228

Value Estimation by Request
3,136 sqft 0.94 AC lot
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1225 Market St
MEDICAL BUILDING

1225 Market St, York, PA 17403-1250

Value Estimation by Request
6,053 sqft 0.48 AC lot
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1550 Rodney Rd
MEDICAL BUILDING

1550 Rodney Rd, York, PA 17408-9715

Value Estimation by Request
10,000 sqft 1.84 AC lot
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1589 Carlisle Rd
MEDICAL BUILDING

1589 Carlisle Rd, York, PA 17408-4528

$685,000
Estimated value
5,320 sqft 1.10 AC lot
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3210 Market St
MEDICAL BUILDING

3210 Market St, York, PA 17402-2506

Value Estimation by Request
4,076 sqft 0.36 AC lot
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1595 Market St
MEDICAL BUILDING

1595 Market St, York, PA 17403-1256

Value Estimation by Request
7,046 sqft 0.35 AC lot
View details
1934 Security Dr
MEDICAL BUILDING

1934 Security Dr, York, PA 17402-4727

Value Estimation by Request
1,260 sqft 0.52 AC lot
View details
947 Queen St
MEDICAL BUILDING

947 Queen St, York, PA 17403-3935

Value Estimation by Request
6,444 sqft 0.44 AC lot
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30 Monument Rd
MEDICAL BUILDING

30 Monument Rd, York, PA 17403-5024

$560,000
Estimated value
11.83 AC lot
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1018 George St
MEDICAL BUILDING

1018 George St, York, PA 17404-2026

Value Estimation by Request
4,242 sqft 0.09 AC lot
View details
1112 Pennsylvania Ave
MEDICAL BUILDING

1112 Pennsylvania Ave, York, PA 17404-1706

Value Estimation by Request
1,340 sqft 0.24 AC lot
View details
85 Wyntre Brooke Dr
MEDICAL BUILDING

85 Wyntre Brooke Dr, York, PA 17403-4536

Value Estimation by Request
2,862 sqft 0.41 AC lot
View details
130 Leaders Hts Rd
MEDICAL BUILDING

130 Leaders Hts Rd, York, PA 17403-5121

$1,755,000
Estimated value
5,592 sqft 1.10 AC lot
View details
2080 Springwood Rd
MEDICAL BUILDING

2080 Springwood Rd, York, PA 17403-4835

Value Estimation by Request
2,418 sqft 0.23 AC lot
View details
1546 Market St
MEDICAL BUILDING

1546 Market St, York, PA 17403-1255

Value Estimation by Request
3,701 sqft 0.37 AC lot
View details
2471 Queen St
MEDICAL BUILDING

2471 Queen St, York, PA 17402-4947

$690,000
Estimated value
5,245 sqft 0.74 AC lot
View details
2319 George St
MEDICAL BUILDING

2319 George St, York, PA 17403-5009

$1,275,000
Estimated value
6,800 sqft 1.01 AC lot
View details

York, PA Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in York, PA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 24,967 square feet of properties for sale, with an estimated market value of $3,441,246.

Sale prices for medical spaces in York, PA start at $325,000, averaging $860,311, and reaching up to $1,511,746 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 76
Office buildings 27
Medical Office Space 12
Coworking space 8
Creative space 1

Demographics Overview

Population 212K
Population Growth (5Y) +5.2%
Median Household Income $76,014
College Educated 30.4%

High-Yield Neighborhoods for Investment

Identify York submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
17403 $918.4K

Taxes & Financing

Tax Rate (average for all types) 3.54%
Property Tax per SF $50.68 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in York County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in York fall within the 100,000+ square foot range.

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