Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Durham, NC Medical Office Space for Sale

    Notify Me
    List
    Map
    Professional Office Condo Near Duke
    $385,000
    1,954 SF

    Professional Office Condo Near Duke

    3200 Croasdaile Drive unit: 101 & 102, Durham, NC 27705

    Office condo in Croasdaile Office Park, convenient location.

    • Prime location in the highly desirable Croasdaile Office Park, minutes from key locations.
    • 1958 SF professional office condo with an ideal layout for medical, legal, financial, or other professional uses.
    • Consists of two suites, offering flexibility to occupy one and expand into the other.
    • End unit with abundant natural light from windows on three sides.
    • Includes reception area, 8 offices, large workroom, 2 bathrooms/break area, lower‑level file storage & attic storage.
    Updated: Feb 28
    View details
    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF

    Colonial Square Office/Medical Building

    4400 Ben Franklin Boulevard, Durham, NC 27704

    Multi-functional commercial building in Durham's Independence Park.

    • Significant income generation from leased area: $227,739 in 2024.
    • Large, multi‑functional commercial building with 21,532 total square feet.
    • Located in a sought‑after office/medical park in northern Durham County.
    • Flexible space suitable for various professional uses (medical, office, education, law).
    • Features include an elevator, ample storage, and a loading dock.
    Updated: Aug 7, 2025
    View details
    Medical Office & Wellness Center
    Contact for pricing
    25,317 SF

    Medical Office & Wellness Center

    Medical office and wellness center in high-traffic Durham location.

    3017 Pickett Rd, Durham, NC 27705
    View details
    Durham Office Near Highway 85
    $750,000
    1,600 SF

    Durham Office Near Highway 85

    Office property close to Highway 85, Duke, and RTP.

    3219 Guess, Durham, NC 27705
    View details
    Renovated Medical Office Condos
    Contact for pricing
    41,588 SF

    Renovated Medical Office Condos

    Newly renovated medical office condos for sale in Durham, NC.

    4020 N Roxboro St, Durham, NC 27704
    View details
    Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 5 Active listings in Durham, NC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 8 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Second-Generation Medical Space Available
    Contact for pricing
    185,637 SF

    Second-Generation Medical Space Available

    Hard-to-find medical space with significant economic advantages in a dynamic community.

    8300 Health Park, Raleigh, NC 27615
    View details
    Chapel Hill Freestanding Building
    $3,200,000
    9,800 SF

    Chapel Hill Freestanding Building

    Two-story building on 0.66 acres in established commercial corridor.

    110 S Estes Dr, Chapel Hill, NC 27514
    View details
    Eastowne Office Condo For Sale
    $325,000
    1,453 SF

    Eastowne Office Condo For Sale

    Office condo in Eastowne, currently occupied by a medical practice.

    150 Providence Rd, Suite 102, Chapel Hill, NC 27514
    View details
    Medical Office Space Available
    Contact for pricing
    25,000 SF

    Medical Office Space Available

    Move-in-ready medical office space in Brier Creek area.

    8851 Ellstree Lane, Raleigh, NC 27617
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cary Parkway Land For Sale
    $1,375,000
    2.29 Acres

    Cary Parkway Land For Sale

    Land available along SW Cary Parkway suitable for various commercial uses.

    1016 Kilarney Ridge Loop, Cary, NC 27511
    View details
    Cleared Commercial Lots in Oxford
    $100,000
    0.51 Acres

    Cleared Commercial Lots in Oxford

    Two commercial lots in downtown Oxford, suitable for various businesses.

    209 Broad Street, Oxford, NC 27565
    View details
    Commercial Lot in Oxford, NC
    $150,000
    0.65 Acres

    Commercial Lot in Oxford, NC

    Commercial lot near Granville Medical Center, ready to build.

    College Street, Oxford, NC 27565
    View details
    Prime Commercial Corner Lot
    $1,200,000
    1.44 Acres

    Prime Commercial Corner Lot

    Exceptional commercial land opportunity in a rapidly growing area.

    629 W Academy Street, Fuquay Varina NC 27526, Fuquay Varina, NC 27526
    View details

    Explore Off-Market Properties in Durham, NC

    Consider similar Off-Market properties in Durham, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3026 Old Chapel Hill Rd

    3026 Old Chapel Hill Rd

    Medical Office Space • 3,935 SF
    Value Estimation by Request
    3026 Old Chapel Hill Rd, Durham, NC 27707
    View details
    5306-102 Hwy

    5306-102 Hwy

    Medical Office Space • 2,028 SF
    Value Estimation by Request
    5306-102 Hwy, Durham, NC 27713
    View details
    249 Nc Hwy 54- –

    249 Nc Hwy 54- –

    Medical Office Space • 8,986 SF
    Value Estimation by Request
    249 Nc Hwy 54- –, Durham, NC 27713
    View details
    249 Nc Highway 54

    249 Nc Highway 54

    Medical Office Space • 3,037 SF
    Value Estimation by Request
    249 Nc Highway 54, Durham, NC 27713
    View details
    4210 Roxboro St

    4210 Roxboro St

    Medical Office Space • 2,408 SF
    Value Estimation by Request
    4210 Roxboro St, Durham, NC 27704
    View details
    1804 Martin Luther King Jr Pkwy

    1804 Martin Luther King Jr Pkwy

    Medical Office Space • 9,992 SF
    Value Estimation by Request
    1804 Martin Luther King Jr Pkwy, Durham, NC 27707
    View details
    4210 Roxboro St

    4210 Roxboro St

    Medical Office Space • 2,408 SF
    Value Estimation by Request
    4210 Roxboro St, Durham, NC 27704
    View details
    249 Nc Highway 54

    249 Nc Highway 54

    Medical Office Space • 3,037 SF
    Value Estimation by Request
    249 Nc Highway 54, Durham, NC 27713
    View details

    Durham, NC Medical Office Space Investment Opportunities Market Analysis

    Explore 13 medical office space for sale in Durham, NC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 91,476 square feet of properties for sale, with an estimated market value of $3,499,000.

    Sale prices for medical spaces in Durham, NC start at $3,499,000, averaging $3,499,000, and reaching up to $3,499,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Popular Searches in Durham, NC

    Popular Categories

    Most Searched ZIP Codes in Durham, NC

    • 27705
    • 27704

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!