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    Santa Clarita, CA Medical Office Space for Sale

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    Two-Story Medical Office Building
    Updated: Jun 11
    Two-Story Medical Office Building

    22621 LYONS AVE, Santa Clarita, CA 91321

    Contact for pricing
    4,604 sqft
    Freestanding two‑story medical office building built in 1992 with ground‑floor medical buildout and second‑floor executive suites
    Two legal parcels on a large lot with dual ingress/egress from Lyons Avenue and Walnut Street
    Second floor includes five executive suites for therapists or professional offices
    Secured on‑site parking with above‑standard medical parking ratio and gated security
    Upgraded HVAC control system and well‑maintained landscaping
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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 1 Active listings in Santa Clarita, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Northridge Commercial/Medical Office Building
    Northridge Commercial/Medical Office Building

    18417 Bryant St, Northridge, CA 91325

    $1,700,000
    3,770 sqft 0.15 AC lot

    Gated commercial/medical office building in the heart of Northridge.

    View details
    Northridge Commercial/Medical Office Building
    Northridge Commercial/Medical Office Building

    18417 Bryant St, Northridge, CA 91325

    $1,700,000
    0.15 AC lot

    Gated commercial/medical office building in the heart of Northridge.

    View details
    Turnkey Dental Practice Office
    Turnkey Dental Practice Office

    17607 Sherman Way 206, Van Nuys, CA 91406

    $350,000

    Established since 2021 with three equipped treatment rooms, X-ray room, and private office in a shopping center setting.

    View details
    Medical Office Building
    Medical Office Building

    15323 Stagg St, Van Nuys, CA 91406

    Contact for pricing

    Medical office building currently operating as a dental office with patient rooms, reception area, and storage.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Parcel with Road Frontage
    Commercial Land Parcel with Road Frontage

    Bear Valley Road, Victorville, CA 92392

    $595,000
    9.77 AC lot

    9.77-acre commercial parcel with long Bear Valley Road frontage for commercial development under zoning C.

    View details
    Commercial Land with Road Frontage
    Commercial Land with Road Frontage

    1 Apple Valley Road, Apple Valley, CA 92308

    $2,500,000
    18.90 AC lot

    Commercial-zoned site with Apple Valley Rd frontage and utilities, including sewer, available for future development.

    View details
    Commercial Land for Future Development
    Commercial Land for Future Development

    Apple Valley Road, Apple Valley, CA 92308

    $3,500,000
    78.70 AC lot

    Large land parcel with multiple zoning designations, including commercial frontage, and utilities available including sewer.

    View details
    Apple Valley Land For Sale
    Apple Valley Land For Sale

    Redbank Rd St, Apple Valley, CA 92307

    $70,000
    6.71 AC lot

    6.71 AC vacant land parcel in Apple Valley, CA.

    View details

    Off-Market Properties in Santa Clarita, CA

    Consider similar Off-Market properties in Santa Clarita, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    22817 Lyons Ave
    MEDICAL BUILDING

    22817 Lyons Ave, Santa Clarita, CA 91321-2819

    Value Estimation by Request
    1,694 sqft 0.17 AC lot
    View details
    27335 Tourney Rd, Unit A-1
    MEDICAL BUILDING

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    Unit A-1
    $1,010,000
    Estimated value
    1.18 AC lot
    View details
    17909 Soledad Cyn Rd
    MEDICAL BUILDING

    17909 Soledad Cyn Rd, Santa Clarita, CA 91387-3210

    $1,335,000
    Estimated value
    20,612 sqft 1.12 AC lot
    View details
    26877 Tourney Rd
    MEDICAL BUILDING

    26877 Tourney Rd, Santa Clarita, CA 91355-1846

    $10,190,000
    Estimated value
    118,157 sqft 4.12 AC lot
    View details
    27107 Tourney Rd
    MEDICAL BUILDING

    27107 Tourney Rd, Santa Clarita, CA 91355-1860

    $10,145,000
    Estimated value
    70,835 sqft 2.48 AC lot
    View details
    27335 Tourney Rd, Unit G2
    MEDICAL BUILDING

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    Unit G2
    $1,055,000
    Estimated value
    1.18 AC lot
    View details
    27335 Tourney Rd, Unit J2
    MEDICAL BUILDING

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    Unit J2
    $730,000
    Estimated value
    1.18 AC lot
    View details
    27335 Tourney Rd, Unit D2
    MEDICAL BUILDING

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    Unit D2
    $1,455,000
    Estimated value
    1.18 AC lot
    View details
    27141 Hidaway Ave
    MEDICAL BUILDING

    27141 Hidaway Ave, Santa Clarita, CA 91351-4131

    Value Estimation by Request
    19,396 sqft 0.73 AC lot
    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    Value Estimation by Request
    38,308 sqft 0.85 AC lot
    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    Value Estimation by Request
    38,308 sqft 0.39 AC lot
    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    $20,265,000
    Estimated value
    38,308 sqft 2.04 AC lot
    View details
    23450 Lyons Ave Ste A
    MEDICAL BUILDING

    23450 Lyons Ave Ste A, Santa Clarita, CA 91321-5779

    $815,000
    Estimated value
    2,307 sqft 0.21 AC lot
    View details
    23928 Lyons Ave
    MEDICAL BUILDING

    23928 Lyons Ave, Santa Clarita, CA 91321-2409

    $3,250,000
    Estimated value
    21,680 sqft 0.17 AC lot
    View details
    22800 Lyons Ave
    MEDICAL BUILDING

    22800 Lyons Ave, Santa Clarita, CA 91321-6800

    $1,055,000
    Estimated value
    5,586 sqft 0.31 AC lot
    View details
    23929 Mcbean Pkwy
    MEDICAL BUILDING

    23929 Mcbean Pkwy, Santa Clarita, CA 91355-4466

    $19,835,000
    Estimated value
    83,698 sqft 8.94 AC lot
    View details
    23450 Lyons Ave Ste B
    MEDICAL BUILDING

    23450 Lyons Ave Ste B, Santa Clarita, CA 91321-5780

    Value Estimation by Request
    2,258 sqft 0.21 AC lot
    View details
    24515 Kansas St
    MEDICAL BUILDING

    24515 Kansas St, Santa Clarita, CA 91321-1719

    Value Estimation by Request
    2,877 sqft 0.29 AC lot
    View details
    22840 Soledad Cyn Rd
    MEDICAL BUILDING

    22840 Soledad Cyn Rd, Santa Clarita, CA 91350-2630

    $655,000
    Estimated value
    4,149 sqft 0.70 AC lot
    View details
    24318 Walnut St
    MEDICAL BUILDING

    24318 Walnut St, Santa Clarita, CA 91321-2924

    $715,000
    Estimated value
    4,697 sqft 0.15 AC lot
    View details
    23861 Mcbean Pkwy
    Medical Office Space

    23861 Mcbean Pkwy, Santa Clarita, CA 91355

    Value Estimation by Request
    46,054 sqft
    View details
    24120-24290 Valencia Blvd
    Neighborhood centers

    24120-24290 Valencia Blvd, Santa Clarita, CA 91355

    Value Estimation by Request
    172,856 sqft
    View details
    27940 Lost Canyon Rd
    Medical Office Space

    27940 Lost Canyon Rd, Santa Clarita, CA 91387

    Value Estimation by Request
    2,600 sqft
    View details

    Santa Clarita, CA Medical Office Space Market Trends and Statistics

    Explore 27 medical office space for sale in Santa Clarita, CA on our real estate platform. These investment opportunities span a total of 4,604 square feet of properties for sale.

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    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 45
    Medical Office Space 14
    Office buildings 10
    Coworking space 3
    Business parks 1

    Demographics Overview

    Population 286K
    Population Growth (5Y) +1.7%
    Median Household Income $124,373
    College Educated 30.0%

    Taxes & Financing

    Tax Rate (average for all types) 1.46%
    Property Tax per SF $34.46 per SF
    Tax Rate vs County Average 0.19 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Los Angeles County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Los Angeles County

    Retail

    Office

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Santa Clarita fall within the 100,000+ square foot range.

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