Advertise
    Santa Clarita, CA
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Warehouse
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Parking & Garage
    • Specialty
    Price
    Price
    $
    $

    Santa Clarita, CA Medical Office Space for Sale

    Notify Me
    List
    Map
    Valencia, CA Newhall, CA Stevenson Ranch, CA
    Two-Story Medical Office Building
    Contact for pricing
    4,604 SF
    Two-Story Medical Office Building

    22621 LYONS AVE, Santa Clarita, CA 91321

    Freestanding two-story facility with a fully built-out medical ground floor and executive suites above, supported by secured parking.
    • Freestanding two‑story medical office building built in 1992 with ground‑floor medical buildout and second‑floor executive suites
    • Two legal parcels on a large lot with dual ingress/egress from Lyons Avenue and Walnut Street
    • Second floor includes five executive suites for therapists or professional offices
    • Secured on‑site parking with above‑standard medical parking ratio and gated security
    • Upgraded HVAC control system and well‑maintained landscaping
    Updated: Jun 11
    View details
    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 1 Active listings in Santa Clarita, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Turnkey Retail Storefront Opportunity
    $899,998
    1,500 SF
    Turnkey Retail Storefront Opportunity

    Well-located retail storefront with recent upgrades, fenced security, and on-site parking for an owner-user seeking stability.

    21627 Sherman Way, Canoga Park, CA 91303

    View details
    Medical Office Suite For Lease
    $2,075,000
    2,749 SF
    Medical Office Suite For Lease

    Ground floor corner suite with high-end finishes, available for lease.

    25425 Orchard Village Rd, Valencia, CA

    View details
    Established Dental Practice in Canoga Park
    $150,000
    Established Dental Practice in Canoga Park

    Dental office opportunity in a thriving Canoga Park location.

    7220 De Soto Avenue, Canoga Park, CA 91304

    View details
    Valencia Retail/Restaurant Space For Sale
    Contact for pricing
    9,000 SF
    Valencia Retail/Restaurant Space For Sale

    Retail and restaurant spaces available in Valencia, California.

    SEC Newhall Ranch Rd. & Copper Hill Dr., Valencia, CA 91355

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Vacant Land with Alley Access
    $2,100,000
    0.17 Acres
    Vacant Land with Alley Access

    Double-lot vacant site zoned QC1 with alley access and existing behind-the-lot parking spaces for flexible development planning.

    1044 S Robertson Blvd, Los Angeles, CA 90035

    View details
    Prime Commercial Parcel Near Amazon
    $595,000
    425,580.00 Acres
    Prime Commercial Parcel Near Amazon

    9.77-acre commercial parcel near Amazon Distribution Center.

    0 Bear Valley Road, Victorville, CA 92392

    View details
    Prime Apple Valley Commercial Land
    $2,500,000
    823,284.00 Acres
    Prime Apple Valley Commercial Land

    18.9 acres of commercial land in a desirable location.

    1 Apple Valley Road, Apple Valley, CA 92308

    View details
    78.7 Acres in Apple Valley
    $3,500,000
    3,428,172.00 Acres
    78.7 Acres in Apple Valley

    Large acreage with commercial zoning and development potential in Apple Valley.

    0 Apple Valley Road, Apple Valley, CA 92308

    View details

    Off-Market Properties in Santa Clarita, CA

    Consider similar Off-Market properties in Santa Clarita, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    22817 Lyons Ave
    MEDICAL BUILDING
    1,694 SF Lot: 0.17 Acres
    Value Estimation by Request

    22817 Lyons Ave, Santa Clarita, CA 91321-2819

    View details
    27335 Tourney Rd, Unit A-1
    MEDICAL BUILDING
    Lot: 1.18 Acres
    Estimated value
    $1,010,000
    Unit A-1

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    View details
    17909 Soledad Cyn Rd
    MEDICAL BUILDING
    20,612 SF Lot: 1.12 Acres
    Estimated value
    $1,335,000

    17909 Soledad Cyn Rd, Santa Clarita, CA 91387-3210

    View details
    26877 Tourney Rd
    MEDICAL BUILDING
    118,157 SF Lot: 4.12 Acres
    Estimated value
    $10,190,000

    26877 Tourney Rd, Santa Clarita, CA 91355-1846

    View details
    27107 Tourney Rd
    MEDICAL BUILDING
    70,835 SF Lot: 2.48 Acres
    Estimated value
    $10,145,000

    27107 Tourney Rd, Santa Clarita, CA 91355-1860

    View details
    27335 Tourney Rd, Unit G2
    MEDICAL BUILDING
    Lot: 1.18 Acres
    Estimated value
    $1,055,000
    Unit G2

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    View details
    27335 Tourney Rd, Unit J2
    MEDICAL BUILDING
    Lot: 1.18 Acres
    Estimated value
    $730,000
    Unit J2

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    View details
    27335 Tourney Rd, Unit D2
    MEDICAL BUILDING
    Lot: 1.18 Acres
    Estimated value
    $1,455,000
    Unit D2

    27335 Tourney Rd, Santa Clarita, CA 91355-2095

    View details
    27141 Hidaway Ave
    MEDICAL BUILDING
    19,396 SF Lot: 0.73 Acres
    Value Estimation by Request

    27141 Hidaway Ave, Santa Clarita, CA 91351-4131

    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING
    38,308 SF Lot: 0.85 Acres
    Value Estimation by Request

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING
    38,308 SF Lot: 0.39 Acres
    Value Estimation by Request

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    View details
    14550 Soledad Cyn Rd
    MEDICAL BUILDING
    38,308 SF Lot: 2.04 Acres

    14550 Soledad Cyn Rd, Santa Clarita, CA 91387-2200

    View details
    23450 Lyons Ave Ste A
    MEDICAL BUILDING
    2,307 SF Lot: 0.21 Acres
    Estimated value
    $815,000

    23450 Lyons Ave Ste A, Santa Clarita, CA 91321-5779

    View details
    23928 Lyons Ave
    MEDICAL BUILDING
    21,680 SF Lot: 0.17 Acres
    Estimated value
    $3,250,000

    23928 Lyons Ave, Santa Clarita, CA 91321-2409

    View details
    22800 Lyons Ave
    MEDICAL BUILDING
    5,586 SF Lot: 0.31 Acres
    Estimated value
    $1,055,000

    22800 Lyons Ave, Santa Clarita, CA 91321-6800

    View details
    23929 Mcbean Pkwy
    MEDICAL BUILDING
    83,698 SF Lot: 8.94 Acres
    Estimated value
    $19,835,000

    23929 Mcbean Pkwy, Santa Clarita, CA 91355-4466

    View details
    23450 Lyons Ave Ste B
    MEDICAL BUILDING
    2,258 SF Lot: 0.21 Acres
    Value Estimation by Request

    23450 Lyons Ave Ste B, Santa Clarita, CA 91321-5780

    View details
    24515 Kansas St
    MEDICAL BUILDING
    2,877 SF Lot: 0.29 Acres
    Value Estimation by Request

    24515 Kansas St, Santa Clarita, CA 91321-1719

    View details
    22840 Soledad Cyn Rd
    MEDICAL BUILDING
    4,149 SF Lot: 0.70 Acres
    Estimated value
    $655,000

    22840 Soledad Cyn Rd, Santa Clarita, CA 91350-2630

    View details
    24318 Walnut St
    MEDICAL BUILDING
    4,697 SF Lot: 0.15 Acres
    Estimated value
    $715,000

    24318 Walnut St, Santa Clarita, CA 91321-2924

    View details
    23861 Mcbean Pkwy
    Medical Office Space
    46,054 SF
    Value Estimation by Request

    23861 Mcbean Pkwy, Santa Clarita, CA 91355

    View details
    24120-24290 Valencia Blvd
    Neighborhood centers
    172,856 SF
    Value Estimation by Request

    24120-24290 Valencia Blvd, Santa Clarita, CA 91355

    View details
    27940 Lost Canyon Rd
    Medical Office Space
    2,600 SF
    Value Estimation by Request

    27940 Lost Canyon Rd, Santa Clarita, CA 91387

    View details

    Santa Clarita, CA Medical Office Space Market Trends and Statistics

    Explore 27 medical office space for sale in Santa Clarita, CA on our real estate platform. These investment opportunities span a total of 4,604 square feet of properties for sale, with an estimated market value of $0.00.

    Sale prices for medical spaces in Santa Clarita, CA start at $0.00, averaging $0.00, and reaching up to $0.00 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 49
    Medical Office Space 11
    Office buildings 7
    Coworking space 6
    Business parks 1

    Demographics Overview

    Population 286K
    Population Growth (5Y) +1.7%
    Median Household Income $124,373
    College Educated 30.0%

    Taxes & Financing

    Tax Rate (average for all types) 1.46%
    Property Tax per SF $34.46 per SF
    Tax Rate vs County Average 0.19 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Los Angeles County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Los Angeles County

    Retail

    Office

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Santa Clarita fall within the 100,000+ square foot range.

    Need Help?

    Reach out if you need assistance with Realmo tools or have questions about your listings

    Contact Us

    Browse Medical Office Space for Sale Near Santa Clarita, CA

    Popular Searches in Santa Clarita, CA

    Popular Categories

    Most Searched ZIP Codes in Santa Clarita, CA

    • 91321

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!