For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Mcallen, TX Medical Offices for Lease

9 results
List
Map
McAllen Retail Plaza Space Available
$15 SF/Yr
14,072 SF

McAllen Retail Plaza Space Available

2000 S Mccoll Rd, McAllen, TX 78503

Retail and medical office spaces for lease near Expressway 83.

  • High‑traffic location, less than half a mile from I‑2/Expwy 83
  • Diverse tenant mix including established brands like Pizza Hut and Subway
  • Close proximity to major hospitals: Rio Grande Regional Hospital and McAllen Medical Hospital
  • Surrounded by big retailers such as Sam's Club, Target, and Walmart
  • Ideal for medical office or walk‑in retail
Updated: Oct 16, 2025
View details
Premier Plaza Commercial Space Available
$4,900 / Mo
2,000 SF

Premier Plaza Commercial Space Available

101 E Expy 83 Hwy, McAllen, TX 78501

Versatile commercial unit in prestigious Rio Grande Valley plaza.

  • Prime location off major expressway ensures maximum exposure and accessibility.
  • Situated next to a hospital district, ideal for medical or healthcare businesses.
  • Located adjacent to the largest shopping center in South Texas, perfect for retail.
  • Unit can be converted to various usable spaces with offered allowance.
  • Located in Premier Plaza, a prestigious commercial plaza.
Updated: Dec 3, 2025
View details
McAllen Office Space For Rent
$3,500 / Mo
2,100 SF

McAllen Office Space For Rent

Office space for rent with excellent visibility near Doctor's Hospital.

5300 N Mccoll Rd, McAllen, TX 78504
View details
Class A Commercial Space
$8,236 / Mo
4,991 SF

Class A Commercial Space

High-end commercial space in McAllen, ideal for professional services.

110 E Savannah Ave, McAllen, TX 78503
View details
McAllen Commercial Space For Lease
$2,000 / Mo
600 SF

McAllen Commercial Space For Lease

Commercial space suitable for pharmacy or medical/office business.

2010 A, McAllen, TX 78501
View details
McAllen Medical Office Space for Lease
$10 SF/Yr
2,400 SF

McAllen Medical Office Space for Lease

2400 sq ft Medical Office, 3-day access

1401 Ridge Rd, McAllen, TX 78503
View details
Prime McAllen Office Space
$24 SF/Yr
4,104 SF

Prime McAllen Office Space

Class A Office Suites, 8 Units Available

309 Nolana Ave, McAllen, TX 78504
View details
Medical Office Space in McAllen
$18 SF/Yr
18,370 SF

Medical Office Space in McAllen

Medical office space for rent in the medical district.

2101 S Col Rowe Blvd, McAllen, TX 78503
View details
Medical Office Space Available
Contact for pricing
10,465 SF

Medical Office Space Available

Medical office suite for rent in McAllen, Texas.

3220 Buddy Owens Ave, McAllen, TX 78504
View details
Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 9 Active listings in Mcallen, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Medical offices for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Stand-Alone Medical Clinic For Lease
$3,930 / Mo
3,275 SF

Stand-Alone Medical Clinic For Lease

Well-laid out medical clinic ready for immediate operation.

1100 W Sam Houston Blvd, Pharr, TX 78577
View details
Prime Pharr Medical Office Space
$20 SF/Yr
24,787 SF

Prime Pharr Medical Office Space

Two Suites Available, High Visibility, Excellent Location

1002 Sam Houston Blvd, Pharr, TX 78577
View details
Edinburg Office Space For Rent
$1.75 SF/Yr
3,187 SF

Edinburg Office Space For Rent

Office space near hospitals and shopping, high traffic area.

3118 Center Point Dr, Edinburg, TX 78539
View details
Edinburg Office Building For Sale
$18 SF/Yr
10,224 SF

Edinburg Office Building For Sale

Prime Edinburg Office, Multi-Tenant Potential

4901 Mccoll Rd, Edinburg, TX 78539
View details

Explore Similar Spaces for Sale in Mcallen, TX

Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

McAllen Medical Property For Sale
$5,469,000
12,996 SF

McAllen Medical Property For Sale

Single-tenant medical property with long-term net lease in McAllen, TX.

1201 Expressway 83 E, McAllen, TX 78503
View details
Free-Standing Office Building For Sale
$535,000
2 SF

Free-Standing Office Building For Sale

Well-maintained 2,250 SF office building in a central location.

1609 N 6Th St, McAllen, TX 78501
View details
McAllen Office Building: Prime Location
Contact for pricing
27,465 SF

McAllen Office Building: Prime Location

Executive & Medical Office Space Available

4600 Military Hwy, McAllen, TX 78503
View details

Mcallen, TX Medical offices Leasing Opportunities Market Analysis

Explore Medical offices leasing options in Mcallen, TX with 12 listings featured on our commercial real estate exchange. The current inventory includes 2,118,627,720 square feet of properties with an estimated lease value of $176 SF/Yr.

Estimated lease rates for Medical offices in Mcallen, TX begin at $10 SF/Yr, with an average of $22 SF/Yr and extend to $40 SF/Yr.
List
Map