Indianapolis, IN Medical Office Space for Rent & Lease

Updated: Sep 19

Freestanding Medical Office Building

5386 W 10th Street, Indianapolis, IN 46224

$2,288/Mo

0.31 AC lot

1,716 SF freestanding medical office building
Single‑story building on a 0.31‑acre parcel
Commercial zoning
Constructed in 1946
Dedicated building identity with signage opportunity

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Updated: Aug 18

Renovated Office Units on Michigan Road

7601 Michigan Road, Indianapolis, IN 46268

$1,800/Mo

0.10 AC lot

Refurbished commercial building constructed in 1900
Flexible floor plan with updated systems and refreshed exterior
0.1‑acre parcel at 7601 Michigan Road, Indianapolis, IN 46268
Commercial zoning
Cable Available

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Office Suite with Conference Room

1109 N Shadeland Avenue, Indianapolis, IN 46219

$1,900/Mo

0.30 AC lot

Several office spaces are arranged with a meeting room, kitchen, and restroom.

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Freestanding Medical Office Building

5386 W 10th St, Indianapolis, IN 46224

$2,288/Mo

1,716 sqft

The occupant has use of the full single-story property and a distinct building identity.

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Medical Office Suite With Exam Rooms

5162 E Stop 11 Road, Indianapolis, IN 46237

$1,840/Mo

5.00 AC lot

Coming-soon suite offers a reception area, private rooms, restroom, and secure file storage for professional users.

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Retail Building with C3 Zoning

9836 Pendleton Pike, Indianapolis, IN 46236

$1,875/Mo

0.31 AC lot

The 1,458-square-foot building offers frontage along Pendleton Pike and access to multiple commercial and service uses.

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Medical Office with Open Gathering Area

6635 E 21st Street, Indianapolis, IN 46219

$11,500/Mo

1.20 AC lot

An ADA-accessible layout includes multiple entrances and a range of private and shared spaces.

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Medical Office Suite

3-5162 Stop 11 Rd, Indianapolis, IN 46217

$1,840/Mo

1,300 sqft

Turn-key medical office layout with reception, five exam rooms, and secure file storage.

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First-Floor Medical Office Suite

8360 S Emerson Avenue, Indianapolis, IN 46237

$12,545/Mo

0.34 AC lot

Configured for clinical operations with exam rooms, treatment areas, staff stations, and administrative offices.

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Flexible Office Units

3834 S Emerson Avenue, Indianapolis, IN 46203

$19 SF/Yr

4.01 AC lot

C1-zoned office property with suites suited to professional services, medical practices, logistics, and administrative operations.

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Renovated Two-Story Medical Office

1026 N Mitthoefer Rd, Indianapolis, IN 46229

$7,385/Mo

9,733 sqft

Flexible workspace includes private rooms and administrative areas for medical and professional office operations.

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Main-Level Office Unit

8915 S Keystone Avenue, Indianapolis, IN 46227

$1,850/Mo

0.58 AC lot

C-3-zoned suite with reception, private offices, kitchenette, and dedicated restroom.

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First-Floor Medical Office Suite

8360 S Emerson Ave, Indianapolis, IN 46237

$12,545/Mo

11,859 sqft

Second-generation clinical space includes exam rooms, procedure and laboratory areas, private offices, and multiple nurses’ stations.

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Turnkey Medical Office Building

6161 Hillside Avenue, Indianapolis, IN 46220

$17 SF/Yr

11,396 sqft

Fully renovated two-story office building with ADA upgrades, updated restrooms, vertical lift, and 60 surface parking spaces.

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Lafayette Road Commercial Space Available

5445 Lafayette Road, Indianapolis, IN 46254

$20 SF/Yr

6,823 sqft

Shell condition space suitable for office, medical, or retail uses.

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Medical Office in Professional Center

5136 E Stop 11 Road 27, Indianapolis, IN 46237

$1,845/Mo

Office space within a professional center, accessed via I-65 South with straightforward local directions.

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Medical Office Space for Lease

5150 E Stop 11 Road 12, Indianapolis, IN 46237

$3,250/Mo

Medical office space available for lease with GPS-friendly directions in Marion County.

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Medical Office Building with Parking

2710 E 62nd St, Indianapolis, IN 46220

Contact for pricing

3,573 sqft

Medical office building formerly used as an eyecare center, offering ADA access and ample parking with visibility on 62nd St.

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Township Line Road Office Space

8081 Township Line Road, Indianapolis, IN 46260

$22.50 SF/Yr

18,815 sqft

First floor office space near Ascension St. Vincent Hospital.

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Medical Office Park with Private Entrances

8849 Shelby Street, Indianapolis, IN 46227

Contact for pricing

75,984 sqft

Medical office buildings with private entrances and patient-at-the-door parking near Community Hospital South.

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Medical Office Space with High Visibility

9333 N Meridian St, Indianapolis, IN 46260

Contact for pricing

3,342 sqft

Medical office space with a refreshed lobby and common areas, centrally located with immediate access to I-465.

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Corner Retail and Medical Space

8028 S Emerson Ave, Indianapolis, IN 46237

Contact for pricing

1,200 sqft

Single suite on the southwest corner, positioned across from Franciscan Health Hospital with strong nearby traffic counts.

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Dental Lab and Office Suite

8840 Commerce Park Pl, Indianapolis, IN 46268

Contact for pricing

20,718 sqft

Move-in ready dental lab and office space with wet lab plumbing, dedicated lab rooms, and a drive-in door.

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Medical Office Space for Lease

8190 Windfall Ln, Camby, IN 46113

Contact for pricing

2,039 sqft

High-visibility medical space joining Heartland Crossing dental tenants in a retail area anchored by major box retailers.

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Indianapolis, IN Medical Office Space Lease Rates & Market Statistics

Explore 49 Medical Office Space listings for lease in Indianapolis, IN on Realmo, a commercial real estate exchange covering the Indianapolis area. The current inventory totals 334,079 square feet of properties — an average of ~6,800 SF per listing.

Asking lease rates for Medical Office Space in Indianapolis start at $16 SF/Yr, average $18.93 SF/Yr, and reach $22.50 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $18.93 SF/Yr, the local average runs 21% below Indiana's state average of $24.04 SF/Yr.

Medical Office Space listings make up 11% of the 440 Office Spaces currently for lease in Indianapolis, with asking rates averaging $18.93 SF/Yr — 12% below the citywide Office Spaces average of $21.49 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (273 listings) and Office buildings (134 listings) elsewhere in the Indianapolis market.