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Medical Office Space with Open Room

6635 E 21st Street, Indianapolis, IN 46219

For Lease
$11,500/Mo

Commercial Lease, Indianapolis, IN

Space Size7,548 SF
Lot Size1.20 Acres
Days on Market116

Property Features for 6635 E 21st Street

General Information

Property type Commercial Lease
Property subtype Office
Zoning C-1
Elementary school district MSD Warren Township
Middle school district MSD Warren Township
High school district MSD Warren Township
Directions GPS Friendly
Subdivision 4905 - Marion - Warren
Standard status Active
APN 490735116002000774
Lot size 1.20 Acres

Taxes and HOA fees

Tax Year 2025
Tax Description Pt W1/2 Ne1/4 S35 T16 R4 Beg 177.94' E Of Nw Core 154.89' S 263.05' W 154.89' N 263.05' To Beg.935 Ac
Tax Annual Amount 11096
Legal Description Pt W1/2 Ne1/4 S35 T16 R4 Beg 177.94' E Of Nw Core 154.89' S 263.05' W 154.89' N 263.05' To Beg.935 Ac

Building Details

Floors in Building 1
Listing Agency: Keller Williams Indy Metro Partners · Keller Williams Realty
Listed By: Shelly Johnson · License #RB14043056
Added: Jul 15 Changed: Nov 4 Last Checked: Nov 7 at 5:06AM
MLS# 22114094

Copyright © 2026 Broker Listing Cooperative®. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

Rey
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Investment Insights

Based on property information with market context.

This 7,548-SF medical office space sits on a 1.2-acre parcel and has an accessible layout. The interior includes three private offices, four restrooms, a conference room, break room, waiting area and a substantial open room. Recent property work includes a roof, water heater, gas furnaces, air-conditioning units, LED lighting, motion-activated floodlights and a resurfaced parking area. Zoning is C-1, and the lease structure is NN.

Two parking areas provide nearly 50 spaces, and multiple entrances serve the building. The configuration also includes a large open area that can accommodate a range of interior arrangements.

Key Highlights

  • 7,548 SF on 1.2 acres
  • Three private offices, four restrooms, a conference room and break room
  • Nearly 50 parking spaces across two lots; multiple building entrances

Property Analytics

Who owns this building? See the owner, sales and loan history
Open Analytics

Current Use

Dr. Megan O'bryan Physician Fiducial Business Centers, ... Consultant RCG Indianapolis Medical Clinic Meliyah Harris Counselor Samantha Saxman Physician

Suggested Use

Top Pick Real Estate Agency Law Firm Dental Office Parking Lot & Garage Electrical Service Garden Center

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type
$2.74 /SF/Yr
CAM

Location Intelligence

Trade Area within ½ mile

552
Businesses Nearby
Under-served
Demand for This Use

Demographics for 46219, IN

36,556
Population
17,028
Households
2.1
Avg Household Size
38
Median Age
26%
College-Educated
86%
High-School Grad
13.0 sq mi
ZIP Area
2,812
Density / Sq Mi
$57,811
Median Household Income
$38,995
Median Earnings
$991
Median Rent
$177,000
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
View Realmo Analytics

Market

Lease Benchmarks for Indianapolis, IN

$18.49 /SF/Yr
Avg Asking Price
$16–$21 /SF/Yr
Price Range
12,228 SF
Avg Space Size

This space is priced 1% below the average of $18.49 /SF/Yr.

Average Price Trend$/SF/Yr for Medical Office Space in Indianapolis, IN

$18.29 Jul
$18.92 Aug
$18.43 Sep
$18.46 Oct

Properties on Market for Medical Office Space in Indianapolis

Jul
Aug
Sep
Oct

Vacancy Rate% for Office in Indianapolis, IN

17.4% 2019
17.8% 2020
19.1% 2021
19.3% 2022
22.2% 2023
22.8% 2024
21.4% 2025

Frequently Asked Questions

What type of property is this?
Medical Office Space - An accessible interior combines private offices, meeting space and a large multipurpose room.
Where is this medical office space located?
The property is located at 6635 E 21st Street Indianapolis, IN.
What is the lease rate?
The lease rate is $11,500/Mo.
What are key features of this property?
This property features: 7,548 SF on 1.2 acres; Three private offices, four restrooms, a conference room and break room; Nearly 50 parking spaces across two lots; multiple building entrances
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