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    Highland, IL
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    Highland, IL Commercial Real Estate for Lease

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    Breese, IL Troy, IL New Baden, IL
    7 results
    Highland Retail/Office/Medical Spaces For Lease
    $14 SF/Yr
    1,775 SF

    Highland Retail/Office/Medical Spaces For Lease

    12603 State Rte 143, Highland, IL 62249

    Office, retail, and medical spaces available for lease in Highland.

    • Located on IL‑143 with nearly 10,000 ADT.
    • Situated at a Lighted Intersection.
    • In front of R.P. Lumber.
    • Suite 8: 2,604 SF – Office/Medical space with Waiting Area, Reception Area, Private Therapy Room, 3 Treatment Bays, Open Therapy Area, Private Office, Storage Room and Restroom.
    • Suite 6: 1,775 SF – Retail/Office space with Open Work Area, Supply Room, Private Office, Showroom, Restroom.
    Updated: Sep 22, 2025
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    Warehouse Space with Flexible Layout
    $6 SF/Yr
    2,437 SF

    Warehouse Space with Flexible Layout

    100-120 Executive Dr, Highland, IL

    2,437 SF warehouse with flexible space and on-site management.

    • Highly visible location right off Highway 40 near Highland entrance.
    • 2,437 SF warehouse space.
    • 8 x 8 OHD (truck height) and 10 x 10 drive‑in door.
    • 12' clear height.
    • Warehouse office with through‑the‑wall heater/AC.
    Updated: Nov 24, 2025
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    New Office Space Available
    $18 SF/Yr
    1,855 SF

    New Office Space Available

    Newly constructed office space near St. Joseph's Hospital.

    5-25 Apex Dr, Highland, IL
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    Remodeled Medical Office Suite
    $10 SF/Yr
    3,040 SF

    Remodeled Medical Office Suite

    3,040 SF remodeled medical office suite for lease.

    1628-1336 Mercantile Dr, Highland, IL
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    Office/Warehouse Space For Lease
    $6 SF/Yr
    3,995 SF

    Office/Warehouse Space For Lease

    3,995 SF office/warehouse space available for lease.

    114 Executive Dr, Highland, IL 62249
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    Remodeled Medical Office Suite
    $10 SF/Yr
    3,040 SF

    Remodeled Medical Office Suite

    Newly remodeled medical office suite in Woodcrest Plaza, Highland, IL.

    1336 Mercantile Dr, Highland, IL 62249
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    Highland Retail/Office Spaces Available
    $14 SF/Yr
    2,604 SF

    Highland Retail/Office Spaces Available

    Retail and office spaces for lease in Highland Shopping Center.

    12603 State Rte 143, Highland, IL 62249
    View details
    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 7 Active listings in Highland, IL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 19 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space in Troy Plaza
    $13 SF/Yr
    1,194 SF

    Retail Space in Troy Plaza

    Retail spaces available in well-located Troy Plaza Shopping Center.

    525-547 Troy Plz, Troy, IL
    View details
    Troy, IL Office Park
    $14 SF/Yr
    11,900 SF

    Troy, IL Office Park

    Office park in Troy, IL with versatile office space.

    505 Buckeye Dr, Troy, IL 62294
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    Retail Space in Orchard Town
    Contact for pricing

    Retail Space in Orchard Town

    New retail development anchored by Meijer in Edwardsville, IL.

    2319 Troy Rd, Edwardsville, IL 62025
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    Retail Space in Edwardsville Marketplace
    Contact for pricing

    Retail Space in Edwardsville Marketplace

    Retail space available in high-traffic Edwardsville Marketplace shopping center.

    2222 Troy Rd, Edwardsville, IL 62025
    View details

    Similar Spaces for Sale in Highland, IL

    Consider Similar Space for Sale. We found 19 Spaces matching your search parameters.

    Prime Retail Building in Highland, IL
    $275,000
    3,080 SF

    Prime Retail Building in Highland, IL

    Well-located retail building with full basement and dedicated parking.

    1018 Laurel Street, Highland, IL 62249
    View details
    Highland Commercial Building For Sale
    $128,000
    0.11 Acres

    Highland Commercial Building For Sale

    Vacant brick building in prime midtown location.

    809 Main Street, Highland, IL 62249
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    High-Visibility Corner Lot in Grantfork
    Contact for pricing
    0.40 Acres

    High-Visibility Corner Lot in Grantfork

    Commercial or residential lot in revitalizing downtown Grantfork, Illinois.

    210 E Pocahontas Road, Highland, IL 62249
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    Prime Residential/Commercial Lot in Highland, IL
    Contact for pricing
    0.24 Acres

    Prime Residential/Commercial Lot in Highland, IL

    Flat, build-ready lot in revitalizing downtown Grantfork, Illinois.

    206 E Pocahontas Road, Highland, IL 62249
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    Highland, IL Commercial Development Land
    $499,900
    11.08 Acres

    Highland, IL Commercial Development Land

    Highly visible 11.08-acre commercial land in a high-traffic area.

    Tbd State Hwy 160, Highland, IL 62249
    View details
    Versatile Medical/Athletic Facility For Sale
    $449,000
    5,375 SF

    Versatile Medical/Athletic Facility For Sale

    5,375 SF building suitable for medical, athletic, or office use.

    1117 Washington St, Highland, IL
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    High Visibility Retail/Office Opportunity
    $295,000

    High Visibility Retail/Office Opportunity

    Retail/office building with high traffic and dedicated parking.

    12571 State Route 143, 2, Highland, IL 62249
    View details
    70+ Acre Highland Farmland
    $826,000
    70.98 Acres

    70+ Acre Highland Farmland

    Versatile 70.98-acre property with tillable ground and wooded areas.

    2912 Wellen Road, Highland, IL 62249
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    Expansive Farmland and Recreational Acreage
    $826,000
    3,091,888 SF

    Expansive Farmland and Recreational Acreage

    70.98-acre parcel with tillable ground and wooded areas.

    2912 Wellen Road, Highland, IL 62249
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    High Visibility Commercial Property
    $295,000

    High Visibility Commercial Property

    Prime location with high traffic and recent upgrades.

    12571 State Route 143 , 2, Highland, IL 62249
    View details
    Versatile Office/Warehouse on Corner Lot
    $719,000
    2,300 SF

    Versatile Office/Warehouse on Corner Lot

    2,196 SF office/warehouse with flexible space and industrial zoning.

    305 Forest Dr, Highland, IL 62249
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    Office/Warehouse on 1.22 Acres
    $250,000
    21,000 SF

    Office/Warehouse on 1.22 Acres

    21,000 SF office/warehouse property for sale.

    1405 Walnut St, Highland, IL
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    Office/Warehouse Space on 1.22 Acres
    $250,000
    21,000 SF

    Office/Warehouse Space on 1.22 Acres

    21,000 SF office/warehouse near major highways.

    1405 Walnut St, Highland, IL 62249
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    Single Tenant Office Building For Sale
    $1,950,000
    12,827 SF

    Single Tenant Office Building For Sale

    Single tenant office building with long-term lease in place.

    115 Executive Dr, Highland, IL
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    Commercial Land for Sale
    Contact for pricing
    2.39 Acres

    Commercial Land for Sale

    Commercial land available for sale in Highland, Illinois.

    5-45 Commercial Ct, Highland, IL
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    New Office Space in Highland
    $129,900
    1,855 SF

    New Office Space in Highland

    Newly constructed 1,855 SF office space for sale.

    5 Apex & 20-25 Apex Dr, Highland, IL 62249
    View details
    Highland Commercial Site for Sale
    $129,900
    1,855 SF

    Highland Commercial Site for Sale

    Land available for build to suit near St. Joseph’s Hospital.

    5 Apex & 20-25 Apex Dr, Highland, IL 62249
    View details

    Highland, IL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Highland, IL with 7 listings featured on our commercial real estate exchange. The current inventory includes 18,746 square feet of properties with an estimated lease value of $78 SF/Yr.

    Estimated lease rates for Commercial real estate in Highland, IL begin at $6 SF/Yr, with an average of $11 SF/Yr and extend to $18 SF/Yr.
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