For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Barnstable, MA Commercial Real Estate for Lease

29 results
List
Map
Class A Hyannis Office Space
$23 SF/Yr
4,051 SF

Class A Hyannis Office Space

248 Stevens St, Hyannis, MA 02601

First-class office space in Hyannis, Cape Cod, with ample parking.

  • Over 4,000 sq ft of Class ''A'' office space across 3 floors with elevator access.
  • Prime location in Hyannis, Cape Cod, close to airport, ferry, downtown, and amenities.
  • Finished lower level with boardroom and additional workspace.
  • First‑class finishes throughout, including moldings and glass doors.
  • Ample private parking with ADA accessibility.
Updated: Feb 15
View details
Hyannis Restaurant Space with Kitchen
$72,000
4,259 SF

Hyannis Restaurant Space with Kitchen

615 Main St, Hyannis, MA 02601

Restaurant space with commercial kitchen in high-traffic Hyannis location.

  • Fully equipped commercial kitchen - ready for immediate use.
  • Prime corner location at the intersection of Main and Sea Streets.
  • High‑traffic area with strong seasonal tourism and year‑round local activity.
  • Located in the Hyannis Main Street Business Improvement District (BID).
  • 4,200 SF ground‑level space with oversized windows and prominent frontage.
Updated: Feb 8
View details
Prime Hyannis Commercial Space
$39,100
2,228 SF

Prime Hyannis Commercial Space

Historic Main Street location ideal for retail, restaurant, or office.

615 Main St, Hyannis, MA 02601
View details
Downtown Hyannis Retail Space Available
$2,325 / Mo
16,184 SF

Downtown Hyannis Retail Space Available

900 SF open retail space on Main Street.

357 Main St, Hyannis, MA 02601
View details
Prime Office Space in Hyannis
$84 SF/Yr
4,004 SF

Prime Office Space in Hyannis

Professional office space for lease in downtown Hyannis.

33 Bassett Ln, Barnstable, MA 02630
View details
Main Street Retail and Residence
$46,200
2,112 SF

Main Street Retail and Residence

Prime Hyannis location with retail space and on-site residence.

547 Main St, Hyannis, MA 02601
View details
Prime Hyannis Retail Space Available
$2,475 / Mo
1,188 SF

Prime Hyannis Retail Space Available

1,200 sq ft retail space in meticulously maintained complex.

11 Enterprise Rd, Hyannis, MA 02601
View details
New Retail/Restaurant Space Available
$33 SF/Yr
4,533 SF

New Retail/Restaurant Space Available

New construction retail/restaurant space at Staples Plaza in Hyannis.

378B Barnstable Rd, Barnstable, MA 02630
View details
Hyannis Office Space Available
$1,900 / Mo
7,792 SF

Hyannis Office Space Available

Office space for rent in Hyannis, multiple units available.

1047 Falmouth Rd, Hyannis, MA 02601
View details
Hyannis Office Space Available
$900 / Mo
7,792 SF

Hyannis Office Space Available

Office space for rent in Hyannis, Massachusetts.

1047 Falmouth Rd, Hyannis, MA 02601
View details
Hyannis Commercial Space Available
$23 SF/Yr
7,792 SF

Hyannis Commercial Space Available

Versatile commercial space in Hyannis with showroom and office potential.

1047 Falmouth Rd, Hyannis, MA 02601
View details
Retail Unit in Hyannis Plaza
$2,438 / Mo
1,500 SF

Retail Unit in Hyannis Plaza

Retail space for lease in Hyannis Plaza, Barnstable, MA.

317 Falmouth Rd, Barnstable, MA 02630
View details
Professional Office Space For Rent
$1,900 / Mo

Professional Office Space For Rent

2,380 SF office space in dynamic commercial corridor.

5 Mark Ln, Hyannis, MA 02601
View details
Former Walgreens End Cap Opportunity
Contact for pricing

Former Walgreens End Cap Opportunity

11,800 SF retail space with high traffic counts.

Barnstable, MA 02648
View details
Commercial Condominium For Lease
$525,000
972 SF

Commercial Condominium For Lease

Commercial condominium for lease with option to purchase.

68 Ctr St, Hyannis, MA
View details
Retail Space Available For Lease
Contact for pricing
17,645 SF

Retail Space Available For Lease

17,645 SF retail space with strong co-tenancy.

665 Iyannough Rd, Barnstable, MA 02601
View details
Cape Cod Mall Land Available
Contact for pricing

Cape Cod Mall Land Available

2.07 AC available within the Cape Cod Mall.

Hyannis, MA 02601
View details
Retail Space Available For Lease
$5,999 / Mo
4,200 SF

Retail Space Available For Lease

Retail space available for lease, totaling 4,200 square feet.

431 Yarmouth Rd, Hyannis, MA 02601
View details
Hyannis Plaza Retail Space
Contact for pricing
1,500 SF

Hyannis Plaza Retail Space

Retail unit in Hyannis Plaza with open floor plan.

489 Bearses Way, Hyannis, MA
View details
Hyannis Restaurant Space For Lease
$0.02 SF/Yr
1,860 SF

Hyannis Restaurant Space For Lease

High-traffic corner, 1860 sq ft, approved site plan.

215 Main Street Hyannis, MA 02601, Hyannis, MA 02601
View details
Prime Retail Space Available
Contact for pricing
2,800 SF

Prime Retail Space Available

2,800 SF retail space for lease in Centerville, MA.

1600 Falmouth Rd, Centerville, MA
View details
Retail Space in Hyannis
Contact for pricing
25,208 SF

Retail Space in Hyannis

Retail property for lease in high-traffic Cape Cod location.

65 Independence Dr, Hyannis, MA
View details
Osterville Office Space For Rent
$1,800 / Mo
1,000 SF

Osterville Office Space For Rent

Professional office suite in desirable Osterville, Cape Cod.

5 Parker Rd, Barnstable, MA 02655
View details
Medical Office Space Near Hospital
$3,500 / Mo
1,864 SF

Medical Office Space Near Hospital

Prime medical office space in Hyannis near Cape Cod Hospital.

51 Main St, Barnstable, MA 02601
View details

Barnstable, MA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Barnstable, MA with 77 listings featured on our commercial real estate exchange. The current inventory includes 3,312,999,360 square feet of properties with an estimated lease value of $323 /Mo.

Estimated lease rates for Commercial real estate in Barnstable, MA begin at $1.39 SF/Yr, with an average of $21 SF/Yr and extend to $84 SF/Yr.
List
Map