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Syracuse, NY Commercial Real Estate for Sale

359 results
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Turnkey Restaurant Opportunity in Syracuse
Pending
$450,000
4,393 SF

Turnkey Restaurant Opportunity in Syracuse

210 W Seneca Tpke, Syracuse, NY 13205

Fully renovated restaurant with equipment included, ready for immediate operation.

  • Turnkey opportunity: Fully renovated indoor dining area with updated infrastructure and well‑maintained equipment, ready for immediate operation.
  • High‑traffic corner location: Excellent exposure in a vibrant neighborhood, drawing customers from schools, community centers, hospitals, and colleges.
  • Versatile business potential: Suitable for various food service concepts or new development.
  • Sale includes the building, equipment, and fixtures, offering a comprehensive package.
  • Recent and upcoming improvements: Garage roof replacement, window glass replacement, and wall masonry work recently completed.
Updated: Nov 3, 2025
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Syracuse Mixed-Use Redevelopment Opportunity
$249,900
4,208 SF

Syracuse Mixed-Use Redevelopment Opportunity

200 W Seneca St & Marcellus St, Syracuse, NY 13204

Mixed-use property in Syracuse's Near West Side redevelopment area.

  • Prime location in the center of the Near West Side redevelopment area.
  • Potential for equity gain through minor renovations.
  • Income potential from a second‑floor apartment to subsidize a business.
  • Multiple funding sources are available.
  • Lot across the street available for parking.
Updated: Sep 10, 2025
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Spacious Income-Producing 9-Bedroom Home
$299,000
3,961 SF

Spacious Income-Producing 9-Bedroom Home

Versatile 9-bedroom home, ideal for residential or income use.

1039 Midland Ave, Syracuse, NY 13205
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Leased Retail Plaza Investment Opportunity
$2,650,000
36,536 SF

Leased Retail Plaza Investment Opportunity

Fully leased six-unit retail plaza in Syracuse, New York.

500 Butternut St, Syracuse, NY 13208
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Syracuse Commercial/Industrial Building For Sale
$399,000
4,408 SF

Syracuse Commercial/Industrial Building For Sale

4,408 sq ft commercial/industrial building in a busy area.

6730 Townline Rd, Syracuse, NY 13211
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610 Oak St, Syracuse
$425,000
6,755 SF

610 Oak St, Syracuse

Historic Firehouse Converted to Office Space

610 Oak St, Syracuse, NY 13203
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Multi-Tenant Income Property in Syracuse
Pending
$1,350,000
19,650 SF

Multi-Tenant Income Property in Syracuse

Well-maintained multi-tenant property with income potential, close to amenities.

404 Oak St, Syracuse, NY 13203
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610 Oak St
$425,000
7,000 SF

610 Oak St

Retail space near downtown.

610 Oak St, Syracuse, NY 13203
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Well-Maintained Duplex in Syracuse
$190,000
2,328 SF

Well-Maintained Duplex in Syracuse

Syracuse duplex with updates, flexible setup, and rental appeal.

154 Parkway Dr, Syracuse, NY 13207
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Charming Multifamily Home with History
$259,900
2,912 SF

Charming Multifamily Home with History

A century-old multifamily home with original charm and separate utilities.

507-509 S Wilbur Ave, Syracuse, NY 13204
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Syracuse Duplex: Investment Opportunity
$205,000
1,704 SF

Syracuse Duplex: Investment Opportunity

Well-maintained Syracuse duplex with steady rental income and tenant amenities.

1318 Oak St, Syracuse, NY 13203
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Corner Lot Mixed-Use Property
$219,900
4,728 SF

Corner Lot Mixed-Use Property

Mixed-use property in Northside neighborhood with storefront and apartment.

826 N Townsend St, Syracuse, NY 13208
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Brazen Cafe
$150,000
725 SF

Brazen Cafe

Investment properties • 725 SF

725 Irving Ave, Syracuse, NY 13210
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Syracuse Mixed-Use Investment
$117,500
0.10 Acres

Syracuse Mixed-Use Investment

Three-unit building, strong rental income.

1516 Valley Dr, Syracuse, NY 13207
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Prime Syracuse Office Building
$425,000
3,960 SF

Prime Syracuse Office Building

Downtown location, highway access, 3960 sq ft

117 Townsend St, Syracuse, NY 13203
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Syracuse Commercial Building - Prime Location
$189,900
3,045 SF

Syracuse Commercial Building - Prime Location

3,045 sq ft commercial space, ideal for various uses.

223 Marcellus St, Syracuse, NY 13204
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Syracuse Commercial Building - Great Investment
$699,000
11,320 SF

Syracuse Commercial Building - Great Investment

11,320 SF building, .76-acre lot, recent upgrades

1417 Valley Dr, Syracuse, NY 13207
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Mattydale Commercial Building For Sale
$200,000
2,688 SF

Mattydale Commercial Building For Sale

High-traffic location, versatile space, great potential.

2229 Brewerton Rd, Syracuse, NY 13211
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Historic Syracuse Bar - Turnkey Operation
$259,000
3,022 SF

Historic Syracuse Bar - Turnkey Operation

Established Bar, Prime Location, Ready to Operate

363 Seneca Tpke, Syracuse, NY 13207
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Syracuse Office Building - Prime Location
$425,000
4,696 SF

Syracuse Office Building - Prime Location

Modern office building, 4696 sq ft, 0.87 acres.

5575 Thompson Rd, Syracuse, NY 13214
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Syracuse Mixed-Use Commercial Property
$450,000
6,000 SF

Syracuse Mixed-Use Commercial Property

Downtown Revitalization Area, High Potential

241 South Ave, Syracuse, NY 13204
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Established Video Game Store in Syracuse
$325,000
10,800 SF

Established Video Game Store in Syracuse

Turnkey Retro Game Business - High Sales

437 Warren St, Syracuse, NY 13202
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Downtown Syracuse Commercial Gem
$1,100,000
32,208 SF

Downtown Syracuse Commercial Gem

Prime location, versatile space, high potential.

323 James St, Syracuse, NY 13203
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Syracuse Commercial Property - Huge Potential
$400,000
8,800 SF

Syracuse Commercial Property - Huge Potential

Prime Syracuse location, 8,800 sqft, redevelopment opportunity.

200 Florence Ave, Syracuse, NY 13205
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Syracuse, NY Commercial Real Estate Investment Opportunities Market Analysis

Explore 4998 commercial real estate investment opportunities in Syracuse, NY with 359 listings featured on our commercial real estate marketplace. The current inventory includes 176,735,701 square feet of properties with an estimated value of $1,340,818,600.

Estimated prices for commercial real estate in Syracuse, NY begin at $50,000, with an average of $558,209 and extend to $27,305,000.

In Syracuse, NY, current investment values show:

  • Mixed-use properties positioned at $400,079
  • Investment properties measuring $400,217
  • Other investment properties assessed at $398,597
  • Retail properties calculated at $673,368
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