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Orangeburg, SC Commercial Real Estate for Sale

89 results
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New Ranch Home with CG Zoning
$250,000
0.16 Acres

New Ranch Home with CG Zoning

109 NW Haddock Rd, Orangeburg, SC 29115

New 3-bedroom ranch with commercial zoning flexibility.

  • Commercial General (CG) zoning allows for residential or commercial use, providing exceptional flexibility.
  • Newly constructed 3‑bedroom, 2‑bath ranch home built in 2025.
  • Single‑story ranch design offers an adaptable floor plan for residential or professional use.
  • Central electric heating and cooling, plus ceiling fans, ensure year‑round comfort.
  • Includes a porch and fenced privacy.
Updated: Jan 5
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Commercial Property in Orangeburg, SC
$195,000
2,016 SF

Commercial Property in Orangeburg, SC

610 Laurel St, Orangeburg, SC 29115

Commercial property for sale with existing lease and tenants.

  • Income‑generating property with existing lease in place ($1800/month)
  • Relatively new roof and plumbing
  • Durable brick construction
  • Central heating and air conditioning
  • Existing tenants described as 'excellent'
Updated: Mar 10, 2025
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Restaurant Building in High-Traffic Area
$150,000
448 SF

Restaurant Building in High-Traffic Area

Vacant restaurant building with high visibility and commercial zoning.

1168 John C. Calhoun Dr, Orangeburg, SC 29115
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Prime Commercial Property in Orangeburg
$60,000

Prime Commercial Property in Orangeburg

High-visibility commercial property in downtown Orangeburg, suitable for various ventures.

141 Boulevard St, Orangeburg, SC 29115
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Prime Commercial Property in Orangeburg
$60,000

Prime Commercial Property in Orangeburg

High-visibility retail storefront in downtown Orangeburg, suitable for various ventures.

141 Boulevard St, Orangeburg, SC 29115
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Prime Orangeburg Commercial Building
$269,000
1,529 SF

Prime Orangeburg Commercial Building

Versatile space, high traffic area, great investment.

750 Russell St, Orangeburg, SC 29115
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 this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer:  CMLS has not reviewed and
$200,000
1,644 SF

this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer: CMLS has not reviewed and

therefore

495 Dantzler St, Orangeburg, SC 29115
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Prime Orangeburg Commercial Land
$475,000
2.22 Acres

Prime Orangeburg Commercial Land

2.22 Acres, High Visibility, $475,000

1474 Charleston Hwy, Orangeburg, SC 29115
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Prime Orangeburg Commercial Lot
$149,900
0.42 Acres

Prime Orangeburg Commercial Lot

0.42-acre lot, $149,900

362 John C Calhoun Dr, Orangeburg, SC 29115
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Orangeburg Industrial Warehouse
$395,000
16,800 SF

Orangeburg Industrial Warehouse

16,800 SF Warehouse - Downtown Location

780 Nottingham St, Orangeburg, SC 29115
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Orangeburg Industrial Warehouse
$11,700,000
260,863 SF

Orangeburg Industrial Warehouse

260,863 SF Warehouse, Newly Renovated

3771 Cameron Rd, Orangeburg, SC 29115
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Prime Orangeburg Storefront
$309,900
5,884 SF

Prime Orangeburg Storefront

5,884 SF Retail Space, Vacant

280 Meeting St, Orangeburg, SC 29115
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Prime Orangeburg Office Building
$399,900
5,840 SF

Prime Orangeburg Office Building

5,840 SF Office Space, $399,900

1408 Russell St, Orangeburg, SC 29115
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Orangeburg Retail Pharmacy Investment
$425,000
15,404 SF

Orangeburg Retail Pharmacy Investment

15,404 SF Pharmacy, 100% Occupied

946 State Rd, Orangeburg, SC 29115
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Magnolia Village Parkway Retail Investment
Contact for pricing

Magnolia Village Parkway Retail Investment

Retail property shadow-anchored to Walmart Supercenter and Lowe’s.

133 Magnolia Vlg Pkwy, Orangeburg, SC 29118
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Mixed-Use Retail Opportunity
Contact for pricing
29,000 SF

Mixed-Use Retail Opportunity

29,000 SF mixed-use or large retail opportunity for sale.

1204 Brickle St, Orangeburg, SC 29118
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Industrial Building on 2.19 Acres
$570,000
13,593 SF

Industrial Building on 2.19 Acres

13,593 SF industrial building with laydown yard near Downtown.

840 Mill St, Orangeburg, SC 29115
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Magnolia Village Parkway Retail Investment
$2,810,000
3,725 SF

Magnolia Village Parkway Retail Investment

Retail property with long-term leases and national tenants.

135 Magnolia Vlg Pkwy, Orangeburg, SC
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Renovated Medical Office with Expansion
$1,300,000
5,676 SF

Renovated Medical Office with Expansion

Medical office with lease, renovation, and expansion potential.

2650 Saint Matthews Rd, Orangeburg, SC 29118
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Retail Property Near Port of Charleston
$6,623,094
4,050 SF

Retail Property Near Port of Charleston

Retail property near logistic thoroughfare and major Southeast metro areas.

3457 Five Chop Rd, Orangeburg, SC 29115
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Orangeburg Flex/Industrial Investment Opportunity
$825,000
13,298 SF

Orangeburg Flex/Industrial Investment Opportunity

Freestanding flex building with warehouse and fenced yard for sale.

351 John C Calhoun Dr, Orangeburg, SC 29115
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Repurposed Retail Space with Lease
$1,320,000
8,320 SF

Repurposed Retail Space with Lease

Retail property with a new 10-year NNN lease.

480 Stonewall Jackson Blvd, Orangeburg, SC 29115
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Versatile Retail/Office with Repair Shop
$189,900
1,990 SF

Versatile Retail/Office with Repair Shop

Retail/office space with repair shop and ample outdoor space.

4166 Rd N, Orangeburg, SC
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Office/Warehouse Space Near Downtown
$1,300,000
17,960 SF

Office/Warehouse Space Near Downtown

Office/warehouse space with drive-through access and fenced backyard.

328 John C Calhoun Dr, Orangeburg, SC 29115
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Orangeburg, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 1568 commercial real estate investment opportunities in Orangeburg, SC with 89 listings featured on our commercial real estate marketplace. The current inventory includes 876,499,594 square feet of properties with an estimated value of $247,204,950.

Estimated prices for commercial real estate in Orangeburg, SC begin at $35,000, with an average of $714,465 and extend to $12,660,000.

In Orangeburg, SC, current investment values show:

  • Retail properties positioned at $722,172
  • Individual retail properties measuring $564,925
  • Office Properties & Spaces assessed at $526,052
  • Industrial properties calculated at $1,275,853
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