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    Wise County, VA Commercial Real Estate for Sale

    24 results
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    Mixed-Use Property in Wise, Virginia
    $350,000
    4,482 SF

    Mixed-Use Property in Wise, Virginia

    528 W Main St, Wise, VA 24293

    Retail space with apartments in the heart of Wise.

    • Established business location with approximately 2000 sq ft of retail/storage space and income potential from day one.
    • Two occupied apartments generate approximately $2500/month in rental income.
    • Prime location in the heart of Wise, VA, with abundant traffic and convenient access to amenities.
    • Potential to add a studio apartment with a private entrance for additional income.
    • Large storefront windows ideal for retail displays.
    Updated: Feb 5
    View details
    Turnkey Commercial Space in Coeburn
    $275,000
    3,600 SF

    Turnkey Commercial Space in Coeburn

    118 NE Grand Ave, Coeburn, VA 24230

    Versatile 3,600 sqft commercial space suitable for various businesses.

    • Turnkey 3600 sqft commercial space suitable for diverse business ventures.
    • Includes a large garage bay previously used for ambulances.
    • Features a full kitchen, 2 bathrooms with showers, and multiple offices/waiting rooms.
    • Built in 2004 and well‑maintained with recent updates including a newer heat pump and paint.
    • Equipped with both heating and cooling via heat pump.
    Updated: Mar 3
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    Coeburn Commercial Unit For Sale
    $40,500
    675 SF

    Coeburn Commercial Unit For Sale

    Commercial unit featuring four rooms, half bath, and parking.

    340 E Front St, Coeburn, VA 24230
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    Refreshed Commercial Building in St. Paul
    $59,900
    1,000 SF

    Refreshed Commercial Building in St. Paul

    Newly refreshed commercial building in the heart of St. Paul.

    16557 Broad St, Saint Paul, VA 24283
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    Coeburn Multifamily Investment Opportunity
    $1,000,000
    10,000 SF

    Coeburn Multifamily Investment Opportunity

    Four properties with immediate income and significant upside potential.

    207 NE Diagonal Ave, Coeburn, VA 24230
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    Mixed-Use Property in Wise, Virginia
    $350,000
    2,462 SF

    Mixed-Use Property in Wise, Virginia

    Commercial space with apartments in the heart of Wise.

    528 W Main St, Wise, VA 24293
    View details
    Turnkey Restaurant in Prime Location
    $199,000
    960 SF

    Turnkey Restaurant in Prime Location

    Well-equipped restaurant for sale in high-traffic area.

    314 E Front St, Coeburn, VA 24230
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    Versatile Commercial Building, Big Stone Gap
    $269,900
    6,768 SF

    Versatile Commercial Building, Big Stone Gap

    Spacious commercial building in Big Stone Gap with endless potential.

    510 E Woods Ave, Big Stone Gap, VA 24219
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    Award-Winning Restaurant with Rental Income
    $229,000
    4,000 SF

    Award-Winning Restaurant with Rental Income

    Turn-key restaurant with rental income in historic Appalachia, Virginia.

    516 W Main St, Appalachia, VA 24216
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    Appalachia, VA Commercial Property
    $90,000
    2,874 SF

    Appalachia, VA Commercial Property

    One-story country church with potential for residential or commercial use.

    817 Oakdale St, Appalachia, VA 24216
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    Mixed-Use Property in Appalachia, VA
    $115,000
    7,164 SF

    Mixed-Use Property in Appalachia, VA

    Commercial and residential spaces with rental income potential in Appalachia.

    106 Kentucky Ave, Appalachia, VA 24216
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    Commercial Property in Downtown Wise
    $475,000
    2.09 Acres

    Commercial Property in Downtown Wise

    2.088 acres with retail space and development potential.

    119 NW Independence Ave, Wise, VA 24293
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    Coeburn Historic Mixed-Use Gem
    $485,000

    Coeburn Historic Mixed-Use Gem

    Three-story building with commercial and residential spaces in historic downtown.

    501 Front St, Coeburn, VA 24230
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    Prime Development Land on US-23
    $350,000
    51.29 Acres

    Prime Development Land on US-23

    50+ acres with US-23 frontage, ideal for commercial or residential.

    S Us Hwy 23, Wise, VA 24293
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    NNN Retail Investment Opportunity
    $1,491,750
    1.73 Acres

    NNN Retail Investment Opportunity

    Leased to Family Dollar with long-term renewal options.

    202 Front St, Coeburn, VA 24230
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    Family Dollar Leased Investment Property
    $1,491,750
    8,400 SF

    Family Dollar Leased Investment Property

    NNN leased investment property with long-term tenant.

    202 Front St, Coeburn, VA 24230
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    Big Stone Gap Corner Property
    Contact for pricing
    9,400 SF

    Big Stone Gap Corner Property

    Prominent corner location suitable for retail or light industrial.

    1809 2Nd Ave E, Big Stone Gap, VA 24219
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    202 Front St
    $1,578,000
    8,400 SF

    202 Front St

    Retail properties & Spaces • 8,400 SF

    202 Front St, Coeburn, VA 24230
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    Downtown Coeburn Mixed-Use Building
    $285,000
    7,722 SF

    Downtown Coeburn Mixed-Use Building

    7,722 SF, 7 Units, Owner Financing Available

    501 High Ave, Coeburn, VA 24230
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    Downtown Norton Commercial Gem
    $425,000
    19,345 SF

    Downtown Norton Commercial Gem

    19,000 SF, 0.5-acre lot, high potential

    702 Park Ave, Norton, VA 24273
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    Prime Norton Commercial Space
    $165,000
    7,248 SF

    Prime Norton Commercial Space

    7,248 SF, 0.5-Acre Lot, $165,000

    508 Park Ave, Norton, VA 24273
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    Coeburn Commercial Space: Turn-Key Salon
    $65,000
    640 SF

    Coeburn Commercial Space: Turn-Key Salon

    Own Your Salon! Prime Coeburn Location.

    410 Quillen Ave, Coeburn, VA 24230
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    Commercial Space on Front Street
    Contact for pricing

    Commercial Space on Front Street

    Large commercial space suitable for various business ventures.

    213 E Front St, Coeburn, VA 24230
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    Historic Building with Unique Signage
    Contact for pricing

    Historic Building with Unique Signage

    Unique historic building with original signage in Coeburn, Virginia.

    417 Front St, Coeburn, VA 24230
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 24 Active Listings in Wise County, VA

    Wise County, VA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 24 commercial real estate for sale in Wise County, VA, showcased through 24 active listings on our real estate platform. These investment opportunities span a total of 2,728,163 square feet of properties for sale, with an estimated market value of $9,019,800.

    Sale prices for business properties in Wise County, VA start at $40,500, averaging $474,726, and reaching up to $1,578,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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