Wise County, VA Commercial Real Estate for Lease

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Retail Storefront with Drive-Through
Updated: Jun 8
Retail Storefront with Drive-Through

102 E 5th Street, Big Stone Gap, VA 24219

$249,000/Mo
1,858 sqft
Corner location on Shawnee Ave and 5th St in downtown Big Stone Gap
Drive‑through window for customer service access
Brand new roof, plus new HVAC and heat pump heating and cooling
Super cold walk‑in coolers included for food storage needs
Large exterior raised programmable LED sign on the building
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Commercial Property in Big Stone Gap
Updated: Dec 29, 2025
Commercial Property in Big Stone Gap

1809 E 2nd Avenue, Big Stone Gap, VA 24219

$350,000/Mo
1,400 sqft
Prominent corner location visible to traffic entering town from US 19.
Nearly an acre of fenced land suitable for various uses.
Potential for re‑use as convenience retail or light industrial.
Existing buildings have utility for service and repair businesses.
Office building can be renovated for retail display.
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Retail/Warehouse Building
Retail/Warehouse Building

213 E Front Street, Coeburn, VA 24230

$3,500/Mo
8,297 sqft

Commercial rental with a very large main room and ample warehouse storage on a 0.37-acre site.

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Retail Building with Drive-Through
Retail Building with Drive-Through

102 5th Street, Big Stone Gap, VA 24219

$249,000 SF/Yr
1,858 sqft

Corner retail building with a drive-through window, brand-new roof and HVAC, and walk-in coolers.

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Historic Retail Space in Coeburn
Historic Retail Space in Coeburn

417 E Front Street, Coeburn, VA 24230

$3,500/Mo
200 sqft

Unique retail space with historical significance in Coeburn, Virginia.

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Retail Space in Stonewall Square
Retail Space in Stonewall Square

121-181 Plaza Rd SW, Wise, VA

Contact for pricing
3,200 sqft

Retail space available in Lexington, Virginia's Stonewall Square shopping mall.

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Commercial Land Site in Wise, VA
Commercial Land Site in Wise, VA

132 Plaza Rd SW, Wise, VA 24293

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Commercial land offering convenient access to major interstates and nearby retail anchored by Tractor Supply and Ashley Furniture.

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Historic Office Building Unit
Historic Office Building Unit

417 Front St E, Coeburn, VA 24230

$3,500/Mo
200 sqft

Former city electric company office unit offered for rent, with required signage and damaged wiring from vandalism.

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Retail Suite in Shopping Center
Retail Suite in Shopping Center

121-181 Plaza Rd SW, Wise, VA 24293

Contact for pricing
3,200 sqft

Available retail space within Stonewall Square shopping mall, anchored by Ollie’s with Food Lion and Harbor Freight among co-tenants.

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Anchored Shopping Center Retail Space
Anchored Shopping Center Retail Space

121-181 Plaza Rd SW, Wise, VA 24293

Contact for pricing
1,441 sqft

Shopping center anchored by Ollie’s Bargain Outlet, with Food Lion and Harbor Freight co-tenants.

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Shopping Center Retail Space
Shopping Center Retail Space

121-181 Plaza Rd SW, Wise, VA 24293

Contact for pricing
1,222 sqft

Retail suite within Stonewall Square shopping mall, anchored by Ollie’s Bargain Outlet with Food Lion and Harbor Freight among co-tenants.

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Anchored Retail Shopping Center
Anchored Retail Shopping Center

121-181 Plaza Rd SW, Wise, VA 24293

Contact for pricing
1,273 sqft

Shopping center anchored by Ollie’s with co-tenants including Food Lion and Harbor Freight, positioned between two major city roads.

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Retail Space in Ridgeview Centre
Retail Space in Ridgeview Centre

129 Ridge Circle, Wise, VA 24293

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11,608 sqft

Retail space available in a busy Wise, Virginia shopping center.

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Powell Valley Shopping Center Space
Powell Valley Shopping Center Space

1941 Neeley Rd, Big Stone Gap, VA 24219

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20,000 sqft

Retail and office spaces available in Big Stone Gap, Virginia.

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Retail and Office Space Available
Retail and Office Space Available

181 Plaza Rd SW, Wise, VA 24293

Contact for pricing
32,236 sqft

Retail and office opportunities in growing Wise, Virginia.

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Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 15 Active listings in Wise County, VA, we suggest exploring alternatives. Similar 36 Properties for Sales.

Similar Spaces for Sale in Wise County, VA

Consider Similar Space for Sale. We found 36 Spaces matching your search parameters.

Self-Serve Car Wash Facility
Self-Serve Car Wash Facility

123 WOODLAND DR, Wise, VA 24293

$764,500
3,822 sqft 0.90 AC lot

Self-serve car wash with 5 covered bays and an automatic bay, positioned near two arterial intersections.

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Award-Winning Restaurant with Rental Income
Award-Winning Restaurant with Rental Income

516 W Main Street, Appalachia, VA 24216

$229,000
4,000 sqft 0.25 AC lot

Turn-key restaurant with rental income in historic Appalachia, Virginia.

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Mixed-Use Store and Apartment
Mixed-Use Store and Apartment

1225 Dante Road, Saint Paul, VA 24283

$150,000
2,240 sqft 0.44 AC lot

A downstairs small store or restaurant space with a separate 2-bed, 1-bath apartment upstairs in a Gen Commercial zone.

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Retail Building with Apartments
Retail Building with Apartments

528 W Main Street, Wise, VA 24293

$325,000
4,482 sqft 0.29 AC lot

Retail space with large storefront windows and storage, plus two occupied apartments generating monthly rental income.

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Award-Winning Restaurant with Rental Income
Award-Winning Restaurant with Rental Income

516 W Main St, Appalachia, VA 24216

$229,000
4,000 sqft

Established BBQ restaurant with rental income in Appalachia, Virginia.

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Mixed-Use Property in Wise, Virginia
Mixed-Use Property in Wise, Virginia

528 W Main Street, Wise, VA 24293

$325,000
2,462 sqft 0.29 AC lot

Commercial space with apartments in the heart of Wise.

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Mixed-Use Building with Retail
Mixed-Use Building with Retail

528 W Main St, Wise, VA 24293

$325,000
2,462 sqft

Mixed-use building with approximately 2,000 sq ft of retail and storage plus two occupied apartments.

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Mixed-Use Property in Appalachia, VA
Mixed-Use Property in Appalachia, VA

106 Kentucky Avenue, Appalachia, VA 24216

$115,000
7,164 sqft 0.60 AC lot

Commercial and residential spaces with rental income potential in Appalachia.

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Commercial Land in Opportunity Zone
Commercial Land in Opportunity Zone

SW Woodland Drive, Wise, VA 24293

$325,000
1.07 AC lot

Prime commercial land in Wise, VA, with development potential.

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Wise County, VA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Wise County, VA with 15 listings featured on our commercial real estate exchange. The current inventory includes 8,697 square feet of properties with an estimated lease value of $425.06 /Mo.

Estimated lease rates for Commercial real estate in Wise County, VA begin at $5.06 SF/Yr, with an average of $141.69 SF/Yr and extend to $210 SF/Yr.
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