Wise County, VA Commercial Real Estate for Lease

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Grocery Store with Drive-Through
Updated: Jun 8
Grocery Store with Drive-Through

102 E 5th Street, Big Stone Gap, VA 24219

Contact for pricing
1,858 sqft 0.30 AC lot
1,858‑square‑foot grocery and convenience store property
Drive‑through window included
0.3‑acre corner parcel at Shawnee Avenue and East 5th Street
Walk‑in coolers and programmable raised LED sign
New HVAC installation with heat pump heating and cooling
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Corner Auto Shop Property
Updated: Dec 29, 2025
Corner Auto Shop Property

1809 E 2nd Avenue, Big Stone Gap, VA 24219

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1,400 sqft 0.82 AC lot
0.82‑acre fenced site spanning 2 lots
1,400 square feet of property improvements
Prominent corner visible to traffic entering town from the eastern exit off US 19
Block construction completed in 1950
Public water and public sewer
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Historic Brick Storefront
Historic Brick Storefront

417 E Front Street, Coeburn, VA 24230

$3,500/Mo
200 sqft

Small street-level commercial unit with public water, public sewer, and a retained electric-company sign.

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Retail Building with Drive-Through
Retail Building with Drive-Through

102 5th Street, Big Stone Gap, VA 24219

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1,858 sqft

Corner retail building with a drive-through window, brand-new roof and HVAC, and walk-in coolers.

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Flexible Commercial Space with Warehouse Storage
Flexible Commercial Space with Warehouse Storage

213 E Front Street, Coeburn, VA 24230

$3,500/Mo
8,297 sqft 0.37 AC lot

Commercial rental with an expansive main area, warehouse storage, and a mix of hardwood and concrete flooring.

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Commercial Land Site in Wise, VA
Commercial Land Site in Wise, VA

132 Plaza Rd SW, Wise, VA 24293

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0.62 AC lot

Commercial land offering convenient access to major interstates and nearby retail anchored by Tractor Supply and Ashley Furniture.

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Retail Space in Stonewall Square
Retail Space in Stonewall Square

121-181 Plaza Rd SW, Wise, VA

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3,200 sqft 13.50 AC lot

Retail space available in Lexington, Virginia's Stonewall Square shopping mall.

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Retail Space in Ridgeview Centre
Retail Space in Ridgeview Centre

129 Ridge Circle, Wise, VA 24293

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11,608 sqft

Retail space available in a busy Wise, Virginia shopping center.

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Historic Office Building Unit
Historic Office Building Unit

417 Front St E, Coeburn, VA 24230

$3,500/Mo
200 sqft

Former city electric company office unit offered for rent, with required signage and damaged wiring from vandalism.

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Based on your search, we've compiled 52 Potential Opportunities for your consideration. Besides 9 Active listings in Wise County, VA, we suggest exploring alternatives. Similar 43 Properties for Sales.

Similar Spaces for Sale in Wise County, VA

Consider Similar Space for Sale. We found 43 Spaces matching your search parameters.

Restaurant and Store with Covered Porch
Restaurant and Store with Covered Porch

231 E 5th Street, Big Stone Gap, VA 24219

$789,900
6,200 sqft 0.60 AC lot

Restaurant property with a separate storefront, commercial kitchen, dining area, and covered outdoor seating.

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Self-Service Car Wash with Automatic Bay
Self-Service Car Wash with Automatic Bay

123 Woodland Dr, Wise, VA 24293

$764,500
3,822 sqft

Woodland Drive facility combines covered wash bays, an automatic lane, coin-changing equipment, and digital memberships.

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Gas Station and Convenience Store
Gas Station and Convenience Store

5722 Cranes Nest Road, Coeburn, VA 24230

$350,000
1,980 sqft 1.31 AC lot

Commercial-zoned property with fuel infrastructure, a separate garage, and adaptable interior space.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

16619 Broad Street, Saint Paul, VA 24283

$525,000
10,000 sqft 0.20 AC lot

Combines occupied residential units with a substantial ground-floor commercial area and dedicated parking.

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Mixed-Use Building with Apartment
Mixed-Use Building with Apartment

1225 Dante Road, Saint Paul, VA 24283

$150,000
2,240 sqft 0.44 AC lot

Ground-floor commercial space is paired with an upstairs two-bedroom apartment.

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Self-Service Car Wash with Automatic Bay
Self-Service Car Wash with Automatic Bay

123 WOODLAND DR, Wise, VA 24293

$764,500
3,822 sqft 0.90 AC lot

Operating wash facility with covered self-service bays, an automatic wash bay, and a coin changer.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

16619 Broad St, Saint Paul, VA 24283

$525,000
10,000 sqft

Fully occupied residential level paired with adaptable ground-floor commercial space.

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Convenience Store With Gas Pumps
Convenience Store With Gas Pumps

5722 Cranes Nest Rd, Coeburn, VA 24230

$350,000
1,980 sqft 1.30 AC lot

Established retail operation with underground fuel tanks, a separate garage, and additional convertible space.

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Stone Automotive Property
Stone Automotive Property

726 Norton Rd, Wise, VA 24293

$229,000
15,068 sqft

Hand-cut stone improvements span both sides of Varner Street, allowing multiple approaches to future commercial use.

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Mixed-Use Property with Apartment
Mixed-Use Property with Apartment

1225 Dante Rd, Saint Paul, VA 24283

$150,000
2,240 sqft

Storefront and restaurant space is paired with an upstairs residential unit near downtown amenities.

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Restaurant with Leased Commercial Space
Restaurant with Leased Commercial Space

516 W Main Street, Appalachia, VA 24216

$229,000
4,000 sqft 0.25 AC lot

Operating barbecue restaurant with conveyed equipment, public utilities, and a separately occupied commercial area.

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Mixed-Use Property with Retail Space
Mixed-Use Property with Retail Space

528 W Main Street, Wise, VA 24293

$325,000
4,482 sqft 0.29 AC lot

R-B-zoned property combines storefront retail, storage, paved parking, and two occupied apartments in Wise.

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Award-Winning Restaurant with Rental Income
Award-Winning Restaurant with Rental Income

516 W Main St, Appalachia, VA 24216

$229,000
4,000 sqft

Established BBQ restaurant with rental income in Appalachia, Virginia.

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Storefront Property with Apartments
Storefront Property with Apartments

528 W Main Street, Wise, VA 24293

$325,000
2,462 sqft 0.29 AC lot

Retail and storage space with two occupied apartments, paved parking, and R-B zoning in Wise.

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Established Animal Hospital For Sale
Established Animal Hospital For Sale

404 Hurricane Rd Ne, Wise, VA 24293

$420,000
2,752 sqft

Veterinary practice in business for 39 years, building only.

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Wise County, VA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Wise County, VA with 9 listings featured on our commercial real estate exchange. The current inventory includes 28,621 square feet of properties with an estimated lease value of $425.06.

Estimated lease rates for Commercial real estate in Wise County, VA begin at $5.06 SF/Yr, with an average of $141.69 SF/Yr and extend to $210 SF/Yr.
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