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    Wise County, VA Commercial Real Estate for Sale

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    Richmond, VA Roanoke, VA Fredericksburg, VA
    35 results
    Car Wash Investment Opportunity
    $764,500
    3,822 SF

    Car Wash Investment Opportunity

    123 WOODLAND DR, Wise, VA 24293

    Car wash with income potential in Wise, Virginia.

    • High Traffic Location on Woodland Drive near Norton Rd & Orby Cantrell Hwy, with 26,937 combined traffic count.
    • Strong Income Potential: Gross income exceeds $160,000 per year.
    • Existing Membership Base: 210 annual digital memberships already in place.
    • Multiple Wash Options, featuring 5 self‑serve bays and 1 automatic wash bay.
    • On‑site coin changer for customer convenience.
    Updated: Mar 4
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    Mixed-Use Property in Wise, VA
    $325,000
    4,482 SF

    Mixed-Use Property in Wise, VA

    528 W Main Street, Wise, VA 24293

    Retail space and apartments in the heart of Wise, Virginia.

    • Established business location with immediate income potential of approximately $2500/month.
    • Approximately 2000 sq ft of versatile retail/office space.
    • Prime location in the heart of Wise, Virginia, with high traffic flow and abundant paved parking.
    • Two well‑maintained apartments included, one 3‑bedroom and one 2‑bedroom, both fully equipped.
    • Potential to add a studio apartment with a private entrance for further income.
    Updated: Jan 29
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    Commercial Property in Wise, Virginia
    $188,000
    1,344 SF

    Commercial Property in Wise, Virginia

    Versatile commercial property on approximately 1 acre in Wise, Virginia.

    118 Washington Road, Wise, VA 24293
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    Award-Winning Restaurant with Rental Income
    $229,000
    4,000 SF

    Award-Winning Restaurant with Rental Income

    Turn-key restaurant with rental income in historic Appalachia, Virginia.

    516 W Main Street, Appalachia, VA 24216
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    Mixed-Use Property in Wise, Virginia
    $325,000
    2,462 SF

    Mixed-Use Property in Wise, Virginia

    Commercial space with apartments in the heart of Wise.

    528 W Main Street, Wise, VA 24293
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    Mixed-Use Store and Apartment
    $150,000
    2,240 SF

    Mixed-Use Store and Apartment

    A downstairs small store or restaurant space with a separate 2-bed, 1-bath apartment upstairs in a Gen Commercial zone.

    1225 Dante Road, Saint Paul, VA 24283
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    Turnkey Commercial Space in Coeburn
    $275,000
    3,600 SF

    Turnkey Commercial Space in Coeburn

    Versatile 3,600 sqft commercial space suitable for various businesses.

    118 NE Grand Avenue, Coeburn, VA 24230
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    Refreshed Commercial Building in St. Paul
    $59,900
    1,000 SF

    Refreshed Commercial Building in St. Paul

    Newly refreshed commercial building in the heart of St. Paul.

    16557 Broad Street, Saint Paul, VA 24283
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    Commercial Land in Opportunity Zone
    $325,000
    1.07 Acres

    Commercial Land in Opportunity Zone

    Prime commercial land in Wise, VA, with development potential.

    SW Woodland Drive, Wise, VA 24293
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    Wise, VA Opportunity Zone Land
    $325,000

    Wise, VA Opportunity Zone Land

    Land in Wise's retail corridor, ideal for retail/flex development.

    SW Woodland Drive, Wise, VA 24293
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    Corner Development Land with Utilities
    $179,000
    21.22 Acres

    Corner Development Land with Utilities

    Level, partially cleared acreage with over 1,000 feet of road frontage and public water and sewer available.

    Hurricane Road, Wise, VA 24293
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    Versatile Commercial Building, Big Stone Gap
    $269,900
    6,768 SF

    Versatile Commercial Building, Big Stone Gap

    Spacious commercial building in Big Stone Gap with endless potential.

    510 E Wood Avenue, Big Stone Gap, VA 24219
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    Mixed-Use Investment Opportunity
    $149,000
    0.20 Acres

    Mixed-Use Investment Opportunity

    Cash-flowing property with commercial space and apartments near amenities.

    201 S 5th Street, Big Stone Gap, VA 24219
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    Commercial Property in Downtown Wise
    $475,000
    8,900 SF

    Commercial Property in Downtown Wise

    2.088 acres with retail space and development potential.

    119 NW Independence Avenue, Wise, VA 24293
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    Turnkey Restaurant in Prime Location
    $199,000
    960 SF

    Turnkey Restaurant in Prime Location

    Profitable, fully equipped restaurant in high-traffic area, ready for new owner.

    314 E Front Street, Coeburn, VA 24230
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    Mixed-Use Property in Appalachia, VA
    $115,000
    7,164 SF

    Mixed-Use Property in Appalachia, VA

    Commercial and residential spaces with rental income potential in Appalachia.

    106 Kentucky Avenue, Appalachia, VA 24216
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    26 Acres in Coeburn, VA
    $265,000
    26.06 Acres

    26 Acres in Coeburn, VA

    26-acre parcel with development potential in Coeburn, Virginia.

    11210 Riverview Road, Coeburn, VA 24230
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    Coeburn Commercial Unit For Sale
    $35,500
    675 SF

    Coeburn Commercial Unit For Sale

    675 SF commercial unit in Coeburn Business Building.

    340 E Front Street, Coeburn, VA 24230
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    Appalachia, VA Commercial Property
    $90,000
    2,874 SF

    Appalachia, VA Commercial Property

    One-story country church with potential for residential or commercial use.

    817 Oakdale Street, Appalachia, VA 24216
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    Prime Land in Opportunity Zone
    $325,000
    1.07 Acres

    Prime Land in Opportunity Zone

    Land in regional hub with tax advantages and high traffic.

    143 Woodland Dr SW, Wise, VA 24293
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    Award-Winning Restaurant with Rental Income
    $229,000
    4,000 SF

    Award-Winning Restaurant with Rental Income

    Established BBQ restaurant with rental income in Appalachia, Virginia.

    516 W Main St, Appalachia, VA 24216
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    Established Animal Hospital For Sale
    $450,000
    2,752 SF

    Established Animal Hospital For Sale

    Veterinary practice in business for 39 years, building only.

    404 NE Hurricane Road, Wise, VA 24293
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    Family Dollar Leased Investment Property
    $1,491,750
    8,400 SF

    Family Dollar Leased Investment Property

    NNN leased investment property with long-term tenant.

    202 FRONT ST, Coeburn, VA 24230
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    Turnkey Restaurant in Prime Location
    $199,000
    0.09 Acres

    Turnkey Restaurant in Prime Location

    Profitable, fully equipped restaurant with loyal customer base and exterior seating.

    314 E Front Street, Coeburn, VA 24230
    View details

    Wise County, VA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Wise County, VA, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 265,420 square feet of properties for sale, with an estimated market value of $6,783,827.

    Sale prices for business properties in Wise County, VA start at $35,500, averaging $308,355, and reaching up to $1,491,750 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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