Wise County, VA Commercial Real Estate for Sale

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31 properties
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Self-Serve Car Wash Facility
Updated: Mar 4
Self-Serve Car Wash Facility

123 WOODLAND DR, Wise, VA 24293

$764,500
3,822 sqft 0.90 AC lot
Car wash built in 2003 with a metal roof
On‑site features 5 covered self‑serve bays plus 1 automatic wash bay
Includes coin changer for the wash facility
Currently has 210 annual digital memberships
Reports overall gross income over $160,000 per year
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Award-Winning Restaurant with Rental Income
Updated: Oct 3, 2025
Award-Winning Restaurant with Rental Income

516 W Main Street, Appalachia, VA 24216

$229,000
4,000 sqft 0.25 AC lot
Established, Award‑Winning BBQ Restaurant: A proven track record with multiple 'Best of the Best' awards and a loyal customer base.
Immediate Rental Income: Includes a second commercial space currently leased to Complete Cardio, generating revenue.
Turn‑Key Operation: Fully equipped restaurant with all equipment included, such as catering supplies, smoker on trailer, and delivery van.
Prime Location: Located in the only town named 'Appalachia' in the Appalachian region, a popular stop for motorsport tourism.
Transition Support: Current owner willing to stay on during the transition for support and guidance.
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Mixed-Use Store and Apartment
Mixed-Use Store and Apartment

1225 Dante Road, Saint Paul, VA 24283

$150,000
2,240 sqft 0.44 AC lot

A downstairs small store or restaurant space with a separate 2-bed, 1-bath apartment upstairs in a Gen Commercial zone.

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Award-Winning Restaurant with Rental Income
Award-Winning Restaurant with Rental Income

516 W Main St, Appalachia, VA 24216

$229,000
4,000 sqft

Established BBQ restaurant with rental income in Appalachia, Virginia.

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Mixed-Use Property in Wise, Virginia
Mixed-Use Property in Wise, Virginia

528 W Main Street, Wise, VA 24293

$325,000
2,462 sqft 0.29 AC lot

Commercial space with apartments in the heart of Wise.

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Retail Building with Apartments
Retail Building with Apartments

528 W Main Street, Wise, VA 24293

$325,000
4,482 sqft 0.29 AC lot

Retail space with large storefront windows and storage, plus two occupied apartments generating monthly rental income.

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Commercial Land in Opportunity Zone
Commercial Land in Opportunity Zone

SW Woodland Drive, Wise, VA 24293

$325,000
1.07 AC lot

Prime commercial land in Wise, VA, with development potential.

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Mixed-Use Building with Retail
Mixed-Use Building with Retail

528 W Main St, Wise, VA 24293

$325,000
2,462 sqft

Mixed-use building with approximately 2,000 sq ft of retail and storage plus two occupied apartments.

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Wise, VA Opportunity Zone Land
Wise, VA Opportunity Zone Land

SW Woodland Drive, Wise, VA 24293

$325,000

Land in Wise's retail corridor, ideal for retail/flex development.

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Mixed-Use Property in Appalachia, VA
Mixed-Use Property in Appalachia, VA

106 Kentucky Avenue, Appalachia, VA 24216

$115,000
7,164 sqft 0.60 AC lot

Commercial and residential spaces with rental income potential in Appalachia.

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Warehouse and Office Space Available
Warehouse and Office Space Available

6512 Main Street, Wise, VA 24293

$149,000
4,200 sqft

Warehouse and office space near US 23 in Wise, VA.

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Corner Development Land with Utilities
Corner Development Land with Utilities

Hurricane Road, Wise, VA 24293

$179,000
21.22 AC lot

Level, partially cleared acreage with over 1,000 feet of road frontage and public water and sewer available.

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Mixed-Use Multifamily with Storefront
Mixed-Use Multifamily with Storefront

201 S 5th Street, Big Stone Gap, VA 24219

$149,000
0.20 AC lot

Income-producing property with storefront tenant and four apartments, including one unit requiring full rehab after fire damage.

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Established Animal Hospital For Sale
Established Animal Hospital For Sale

404 NE Hurricane Road, Wise, VA 24293

$425,000
2,752 sqft

Veterinary practice in business for 39 years, building only.

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Commercial Property in Downtown Wise
Commercial Property in Downtown Wise

119 NW Independence Avenue, Wise, VA 24293

$475,000
8,900 sqft 2.09 AC lot

2.088 acres with retail space and development potential.

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Appalachia, VA Commercial Property
Appalachia, VA Commercial Property

817 Oakdale Street, Appalachia, VA 24216

$90,000
2,874 sqft 0.19 AC lot

One-story country church with potential for residential or commercial use.

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Prime Land in Opportunity Zone
Prime Land in Opportunity Zone

143 Woodland Dr SW, Wise, VA 24293

$325,000
1.07 AC lot

Land in regional hub with tax advantages and high traffic.

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Leased Retail Building with Parking
Leased Retail Building with Parking

202 FRONT ST, Coeburn, VA 24230

$1,491,750
8,400 sqft 1.73 AC lot

Retail building leased to Family Dollar with five 5-year terms starting July 1, 2024 and 31 parking spaces.

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Big Stone Gap Corner Property
Big Stone Gap Corner Property

1809 2nd Ave E, Big Stone Gap, VA

$350,000
9,400 sqft 0.82 AC lot

Prominent corner location suitable for retail or light industrial.

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Coeburn Commercial Unit For Sale
Coeburn Commercial Unit For Sale

340 E Front Street, Coeburn, VA 24230

$35,500
675 sqft 0.02 AC lot

675 SF commercial unit in Coeburn Business Building.

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Family Dollar Leased Investment Property
Family Dollar Leased Investment Property

202 Front St, Coeburn, VA 24230

$1,491,750
8,400 sqft

Leased to Family Dollar, offering an 8% cap rate.

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Mixed-Use Building with Apartments
Mixed-Use Building with Apartments

501 Front Street, Coeburn, VA 24230

$485,000

Three-story mixed-use building on Front Street includes commercial space plus multiple apartments across upper floors.

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Renovated Commercial Building For Sale
Renovated Commercial Building For Sale

11231 Indian Creek Road, Pound, VA 24279

$193,333
1,624 sqft

Renovated commercial building with drive-through and security system.

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Prime Development Land on US-23
Prime Development Land on US-23

S Us Hwy 23, Wise, VA 24293

$350,000
51.29 AC lot

50+ acres with US-23 frontage, ideal for commercial or residential.

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Wise County, VA Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Wise County, VA, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 86,254 square feet of properties for sale, with an estimated market value of $7,684,333.

Sale prices for business properties in Wise County, VA start at $35,500, averaging $404,438, and reaching up to $1,491,750 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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