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Orangeburg, SC Commercial Real Estate for Sale

82 results
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New Ranch Home with CG Zoning
$235,000
0.16 Acres

New Ranch Home with CG Zoning

109 NW Haddock Rd, Orangeburg, SC 29115

3-bedroom home with commercial zoning flexibility in Orangeburg, SC.

  • Commercial General (CG) zoning allows for residential or commercial use, providing exceptional flexibility.
  • Newly constructed 3‑bedroom, 2‑bath single‑story ranch home.
  • Adaptable floor plan suitable for residential living or conversion to professional/commercial space.
  • Ideal for owner‑occupants seeking residential living with future commercial flexibility or live/work potential.
  • Central heating and air conditioning.
Updated: Feb 11
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Versatile Commercial Property in Orangeburg
$185,000
1,750 SF

Versatile Commercial Property in Orangeburg

495 Dantlzer St, Orangeburg, SC 29115

Excellent investment for beauty, salon, spa, or health business.

  • Versatile commercial property ideal for beauty shop, salon, spa, or health and beauty‑related business.
  • Eight separate rooms and four separate entrances allow for flexible use.
  • Ample parking on a corner lot.
  • Separate garage with 12x24 roll‑up door provides additional storage.
  • Two separate HVAC units and breaker boxes support high‑demand commercial use.
Updated: Feb 6
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Orangeburg Commercial Property with Warehouse
$249,900
6,000 SF

Orangeburg Commercial Property with Warehouse

Two buildings ideal for office, retail, or warehouse use.

2874 Bamberg Rd, Orangeburg, SC 29115
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Commercial Property in Orangeburg, SC
$195,000
2,016 SF

Commercial Property in Orangeburg, SC

Commercial property for sale with existing lease and tenants.

610 Laurel St, Orangeburg, SC 29115
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Prime Commercial Property in Orangeburg
Contact for pricing

Prime Commercial Property in Orangeburg

High-visibility commercial property in downtown Orangeburg, suitable for various ventures.

141 Boulevard St, Orangeburg, SC 29115
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Prime Commercial Property in Orangeburg
Contact for pricing

Prime Commercial Property in Orangeburg

High-visibility retail storefront in downtown Orangeburg, suitable for various ventures.

141 Boulevard St, Orangeburg, SC 29115
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Prime Orangeburg Commercial Building
$269,000
1,529 SF

Prime Orangeburg Commercial Building

Versatile space, high traffic area, great investment.

750 Russell St, Orangeburg, SC 29115
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 this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer:  CMLS has not reviewed and
$200,000
1,644 SF

this property encourages creativity and customization. Don't miss the chance to make this commercial space your own while generating steady income. Disclaimer: CMLS has not reviewed and

therefore

495 Dantzler St, Orangeburg, SC 29115
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Prime Orangeburg Commercial Land
$475,000
2.22 Acres

Prime Orangeburg Commercial Land

2.22 Acres, High Visibility, $475,000

1474 Charleston Hwy, Orangeburg, SC 29115
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Prime Orangeburg Commercial Lot
$149,900
0.42 Acres

Prime Orangeburg Commercial Lot

0.42-acre lot, $149,900

362 John C Calhoun Dr, Orangeburg, SC 29115
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Orangeburg Industrial Warehouse
$395,000
16,800 SF

Orangeburg Industrial Warehouse

16,800 SF Warehouse - Downtown Location

780 Nottingham St, Orangeburg, SC 29115
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Orangeburg Industrial Warehouse
$11,700,000
260,863 SF

Orangeburg Industrial Warehouse

260,863 SF Warehouse, Newly Renovated

3771 Cameron Rd, Orangeburg, SC 29115
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Prime Orangeburg Storefront
$309,900
5,884 SF

Prime Orangeburg Storefront

5,884 SF Retail Space, Vacant

280 Meeting St, Orangeburg, SC 29115
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Prime Orangeburg Office Building
$399,900
5,840 SF

Prime Orangeburg Office Building

5,840 SF Office Space, $399,900

1408 Russell St, Orangeburg, SC 29115
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Orangeburg Retail Pharmacy Investment
$425,000
15,404 SF

Orangeburg Retail Pharmacy Investment

15,404 SF Pharmacy, 100% Occupied

946 State Rd, Orangeburg, SC 29115
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Magnolia Village Parkway Retail Investment
Contact for pricing

Magnolia Village Parkway Retail Investment

Retail property shadow-anchored to Walmart Supercenter and Lowe’s.

133 Magnolia Vlg Pkwy, Orangeburg, SC 29118
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Mixed-Use Retail Opportunity
Contact for pricing
29,000 SF

Mixed-Use Retail Opportunity

29,000 SF mixed-use or large retail opportunity for sale.

1204 Brickle St, Orangeburg, SC 29118
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Industrial Building on 2.19 Acres
Contact for pricing
13,593 SF

Industrial Building on 2.19 Acres

13,593 SF industrial building with laydown yard near Downtown.

840 Mill St, Orangeburg, SC 29115
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Retail Site in Orangeburg, SC
Contact for pricing

Retail Site in Orangeburg, SC

1.32-acre retail site with 4,869 SF available.

Orangeburg, SC 29118
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Magnolia Village Parkway Retail Investment
$2,810,000
3,725 SF

Magnolia Village Parkway Retail Investment

Retail property with long-term leases and national tenants.

135 Magnolia Vlg Pkwy, Orangeburg, SC
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Retail Property Near Port of Charleston
$6,623,094
4,050 SF

Retail Property Near Port of Charleston

Retail property near logistic thoroughfare and major Southeast metro areas.

3457 Five Chop Rd, Orangeburg, SC 29115
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Orangeburg Flex/Industrial Investment Opportunity
$825,000
13,298 SF

Orangeburg Flex/Industrial Investment Opportunity

Freestanding flex building with warehouse and fenced yard for sale.

351 John C Calhoun Dr, Orangeburg, SC 29115
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Versatile Retail/Office with Repair Shop
$189,900
1,990 SF

Versatile Retail/Office with Repair Shop

Retail/office space with repair shop and ample outdoor space.

4166 Rd N, Orangeburg, SC
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Office/Warehouse Space Near Downtown
Contact for pricing
17,960 SF

Office/Warehouse Space Near Downtown

Office/warehouse space with drive-through access and fenced backyard.

328 John C Calhoun Dr, Orangeburg, SC 29115
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Orangeburg, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 1568 commercial real estate investment opportunities in Orangeburg, SC with 82 listings featured on our commercial real estate marketplace. The current inventory includes 871,764,622 square feet of properties with an estimated value of $245,618,200.

Estimated prices for commercial real estate in Orangeburg, SC begin at $35,000, with an average of $722,406 and extend to $12,660,000.

In Orangeburg, SC, current investment values show:

  • Retail properties positioned at $716,869
  • Individual retail properties measuring $560,359
  • Office Properties & Spaces assessed at $516,506
  • Industrial properties calculated at $1,225,344
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