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    Clemson, SC Commercial Real Estate for Sale

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    Commercial Space in Downtown Clemson
    Pending
    $699,000

    Commercial Space in Downtown Clemson

    105 Sloan St, Clemson, SC 29631

    Rare opportunity to purchase commercial space in downtown Clemson.

    • Prime commercial location in downtown Clemson.
    • Approximately 2600 sq ft of commercial space.
    • Two separate spaces: 1300 sq ft upstairs and 1300 sq ft downstairs.
    • Downstairs space has an established business with a lease until 8/31/2028, providing immediate rental income.
    • Upstairs space is currently vacant, offering immediate occupancy or rental opportunity.
    Updated: Dec 14, 2025
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    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    990 Tiger Blvd, Clemson, SC 29631

    Commercial building in Clemson with ample parking and high traffic.

    • High‑traffic location on Hwy 123 with 30,000 vehicles per day.
    • Large 6000 square foot commercial building.
    • Ample parking available.
    • Durable construction with block and metal siding.
    • Metal roof for longevity.
    Updated: Nov 11, 2025
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    Clemson Development Opportunity
    $1,299,774
    7.66 Acres

    Clemson Development Opportunity

    7+ acres zoned for hotel or multifamily development near Clemson.

    76 Hwy W, Clemson, SC 29631
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    Gorgeous Townhome in Patrick Square
    $432,500
    1,620 SF

    Gorgeous Townhome in Patrick Square

    Practically new 2-bedroom, 2.5-bath townhome with modern features and amenities.

    174 Thomas Green Blvd, Clemson, SC 29631
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    Clemson Commercial Land - 7.66 Acres
    $1,299,774
    7.66 Acres

    Clemson Commercial Land - 7.66 Acres

    Prime Clemson location, ideal for hotel or multi-family development.

    00 Hwy 76 Hwy, Clemson, SC 29631
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    Based on your search, we've compiled 307 Potential Opportunities for your consideration. Besides 5 Active listings in Clemson, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 294 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Land Outparcels Available
    Contact for pricing

    Commercial Land Outparcels Available

    Two outparcels available on Calhoun Memorial Highway.

    608 Issaqueena Trl, Central, SC 29630
    View details
    Prime Central, SC Commercial Land
    Contact for pricing
    4.16 Acres

    Prime Central, SC Commercial Land

    4.16 Acres, Two Parcels Available

    608 Issaqueena Trl, Central, SC 29630
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    Luxury Condo Hotel Near Campus
    $292,110

    Luxury Condo Hotel Near Campus

    Studio condo in luxury hotel with rental management options.

    13500 Clemson Blvd, Seneca, SC 29678
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    Studio Condo Near Clemson Campus
    $270,000

    Studio Condo Near Clemson Campus

    Studio condo near Clemson University with rental management options.

    13500 Clemson Blvd, Seneca, SC 29678
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Medical Office Site Opportunity
    $499,000

    Medical Office Site Opportunity

    Prime location near Clemson University in Patrick Square.

    Chapman Hl Rd, Clemson, SC 29631
    View details
    Clemson Land for Multifamily Development
    $1,299,774
    7.66 Acres

    Clemson Land for Multifamily Development

    7+ acres in Clemson, SC, ideal for multifamily or hotel development.

    00 76 Hwy, Clemson, SC 29631
    View details
    Land for Medical Office Building
    $499,000

    Land for Medical Office Building

    Land available with approved plans for medical office building.

    105 Chapman Hl Rd, Clemson, SC
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    Clemson Land Parcels Available
    Contact for pricing

    Clemson Land Parcels Available

    Two outparcels available in Clemson, South Carolina.

    608 Issaqueena Trl, Clemson, SC 29631
    View details

    Explore Off-Market Properties in Clemson, SC

    Consider similar Off-Market properties in Clemson, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    500 Old Greenville Hwy

    500 Old Greenville Hwy

    Restaurants • 76,566 SF
    Value Estimation by Request
    500 Old Greenville Hwy, Clemson, SC 29631
    View details
    107 Canoy Ln

    107 Canoy Ln

    Retail properties • 44,128 SF
    Value Estimation by Request
    107 Canoy Ln, Clemson, SC 29631
    View details
    125 Anderson Hwy

    125 Anderson Hwy

    Office Properties & Spaces • 11,621 SF
    Value Estimation by Request
    125 Anderson Hwy, Clemson, SC 29631
    View details
    Franchise Restaurant For Sale Near Clemson University!

    Franchise Restaurant For Sale Near Clemson University!

    Restaurants • 1,525 SF
    Value Estimation by Request
    0 Franchise Restaurant For Sale Near Clemson University!, Clemson, SC 29631
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    Sub Franchise for Sale with Growth Potential! Invest In Success Est

    Sub Franchise for Sale with Growth Potential! Invest In Success Est

    Restaurants • 1,500 SF
    Value Estimation by Request
    Sub Franchise for Sale with Growth Potential! Invest In Success Est, Clemson, SC 29631
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    114 Earle St

    114 Earle St

    Restaurants • 253,000 SF
    Value Estimation by Request
    114 Earle St, Clemson, SC 29631
    View details
    1067 Tiger Blvd

    1067 Tiger Blvd

    Restaurants
    Value Estimation by Request
    1067 Tiger Blvd, Clemson, SC 29631
    View details
    00 Hwy 76 Hwy

    00 Hwy 76 Hwy

    Commercial real estate • 7.66 Acres
    Value Estimation by Request
    00 Hwy 76 Hwy, Clemson, SC 29631
    View details
    111 Cadet

    111 Cadet

    Commercial real estate • 5,228 SF
    Value Estimation by Request
    111 Cadet, Clemson, SC 29631
    View details
    Restaurant for Sale in Thriving Clemson SC! Exciting Opportunity Turn Ky

    Restaurant for Sale in Thriving Clemson SC! Exciting Opportunity Turn Ky

    Restaurants • 1,500 SF
    Value Estimation by Request
    Restaurant for Sale in Thriving Clemson SC! Exciting Opportunity Turn Ky, Clemson, SC 29631
    View details
    215 Charleston Ave

    215 Charleston Ave

    APARTMENT HOUSE (UNDER 5 UNITS) • 3,650 SF
    Value Estimation
    $1,660,000
    215 Charleston Ave, Clemson, SC 29631-2857
    View details
    1380 Tiger Blvd

    1380 Tiger Blvd

    FINANCIAL BUILDING • 3,228 SF
    Value Estimation
    $355,000
    1380 Tiger Blvd, Clemson, SC 29631-2602
    View details
    673 Old Greenville Hwy

    673 Old Greenville Hwy

    PROFESSIONAL CLUBS/ASSOCIATIONS • 9,869 SF
    Value Estimation by Request
    673 Old Greenville Hwy, Clemson, SC 29631-3361
    View details
    1015 Old Stone Church Rd

    1015 Old Stone Church Rd

    AUTO REPAIR, GARAGE • 9,184 SF
    Value Estimation
    $280,000
    1015 Old Stone Church Rd, Clemson, SC 29631-2240
    View details
    501 Frst Ln Ste A

    501 Frst Ln Ste A

    OFFICE BUILDING • 5,196 SF
    Value Estimation
    $320,000
    501 Frst Ln Ste A, Clemson, SC 29631-2621
    View details
    100 Thomas Grn Blvd

    100 Thomas Grn Blvd

    PROFESSIONAL CLUBS/ASSOCIATIONS • 7,692 SF
    Value Estimation by Request
    100 Thomas Grn Blvd, Clemson, SC 29631-2165
    View details
    131 Freedom Dr, Unit E

    131 Freedom Dr, Unit E

    APARTMENT HOUSE (UNDER 5 UNITS) • 2,415 SF
    Value Estimation
    $1,085,000
    131 Freedom Dr, Clemson, SC 29631-2634
    View details
    207 Pendleton Rd

    207 Pendleton Rd

    COMMERCIAL (GENERAL) • 3,038 SF
    Value Estimation
    $790,000
    207 Pendleton Rd, Clemson, SC 29631-2206
    View details
    141 Cochran Rd, Unit 1

    141 Cochran Rd, Unit 1

    APARTMENT HOUSE (UNDER 5 UNITS) • 3,360 SF
    Value Estimation
    $220,000
    141 Cochran Rd, Clemson, SC 29631-2610
    View details

    Clemson, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 282 commercial real estate investment opportunities in Clemson, SC on our commercial real estate marketplace. The current inventory includes 6,942,378 square feet of properties with an estimated value of $107,953,312.

    Estimated prices for commercial real estate in Clemson, SC begin at $105,000, with an average of $1,384,016 and extend to $17,830,000.

    In Clemson, SC, current investment values show:

    • Retail properties positioned at $1,460,961
    • Office Properties & Spaces measuring $793,947
    • Individual retail properties assessed at $1,384,686
    • Multifamily properties calculated at $2,229,659
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    Browse Commercial real estate for Sale Near Clemson, SC

    Popular Searches in Clemson, SC

    Most Searched ZIP Codes in Clemson, SC

    • 29631

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