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    Research Triangle Park, NC Commercial Real Estate for Sale

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    Raleigh, NC Chapel Hill, NC Morrisville, NC
    138 listings
    Retail Building with Basement Access
    $5,000,000
    8,000 SF
    Retail Building with Basement Access

    501 N Mangum Street, Durham, NC 27701

    Freestanding retail building with a separately accessible basement, fenced lot, and parking for flexible redevelopment or occupancy.
    • 8,000 SF building in downtown Durham (former Public Hardware retail).
    • Includes a 4,000 SF basement accessible via walk‑in and roll‑up doors.
    • Fenced lot with parking on site.
    • City of Durham previously approved for a 15‑story building with 4 parking levels and 200+ multi‑family units (approval listed under A - D2300216 / 501 N Mangum Street).
    • Public utilities: public water and public sewer.
    Updated: Jun 10
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    Durham Commercial Land Opportunity
    $1,300,000
    2,386 SF
    Durham Commercial Land Opportunity

    3421 N Duke Street, Durham, NC 27704

    Two adjacent properties for sale in Durham's growing corridor.
    • Two adjacent properties (3413 & 3421 N Duke St) sold together, offering a larger footprint.
    • Prime location on the growing N Duke Street corridor with strong visibility.
    • Excellent potential for investors, small business owners, or future development.
    • Spacious lots provide flexibility for various uses (office, service‑based business, redevelopment).
    • Conveniently located minutes from downtown Durham, Duke University, and major highways.
    Updated: Apr 9
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    Established Durham Mechanical Shop For Sale
    $1,000,000
    4,000 SF
    Established Durham Mechanical Shop For Sale

    Income-producing mechanical shop with five service bays and ample parking.

    2410 Angier Avenue, Durham, NC 27703

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    Live-Work Craftsman Office Bungalow
    $499,500
    1,922 SF
    Live-Work Craftsman Office Bungalow

    1930s craftsman home in an Office/Institutional district offering multiple rooms for live-work or office use.

    1814 Chapel Hill Road, Durham, NC 27707

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    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF
    Colonial Square Office/Medical Building

    Multi-functional commercial building in Durham's Independence Park.

    4400 Ben Franklin Boulevard, Durham, NC 27704

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    Development Opportunity in Growing Area
    $750,000
    2.10 Acres
    Development Opportunity in Growing Area

    2.1 acre lot in fast growing Durham area.

    800 Olive Branch Road, Durham, NC 27703

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    Durham Commercial Investment Opportunity
    $730,000
    2,640 SF
    Durham Commercial Investment Opportunity

    Tenant-occupied commercial property in Durham with high visibility.

    901 E Trinity Avenue, Durham, NC 27704

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    Prime Development Site in Durham
    $150,000
    0.46 Acres
    Prime Development Site in Durham

    High-visibility commercial land near downtown Durham with significant frontage.

    3133 Fayetteville St, Durham, NC 27707

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    Land Parcel Near Research Triangle
    $590,000
    7.69 Acres
    Land Parcel Near Research Triangle

    7.8-acre land parcel in southeast Durham near RTP.

    4348 S Alston Avenue, Durham, NC 27713

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    Colonial Duplex Near Downtown Durham
    $310,000
    1,892 SF
    Colonial Duplex Near Downtown Durham

    Two-unit property near downtown Durham with renovation potential.

    708 S Roxboro Street, Durham, NC 27707

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    Retail Building with Basement Access
    $5,000,000
    8,000 SF
    Retail Building with Basement Access

    Retail building offers a second level with walk-in and roll-up access plus fenced lot parking for operations or reuse.

    501 N Mangum Street Unit 501, Durham, NC 27701

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    90+ Acres in North Durham
    $2,995,000
    90.66 Acres
    90+ Acres in North Durham

    Rare, versatile land suitable for development or private estate.

    6900 / 6918 Russell Road, Durham, NC 27712

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    Durham Land Near Bethesda Church
    $170,000
    0.26 Acres
    Durham Land Near Bethesda Church

    Vacant lot near church and school, potential for small business.

    1820 S Miami Boulevard, Durham, NC 27703

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    Multi-Tenant Retail Corner Building
    $850,000
    Multi-Tenant Retail Corner Building

    Single-story retail corner property with an in-place tenant through 2028, offering stable investment income.

    1715 Holloway St, Durham, NC 27703

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    Industrial Flex with Laydown Yard
    $1,500,000
    6,831 SF
    Industrial Flex with Laydown Yard

    Leased industrial flex with heated warehouse, office, and concrete laydown yard on about 1.4 acres.

    1101 E Cornwallis, Durham, NC 27713

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    Renovated Office Buildings For Sale
    $2,375,100
    5,220 SF
    Renovated Office Buildings For Sale

    Two renovated office buildings ideal for owner-user or investment.

    2117 Guess Road, Durham, NC 27705

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    33 Acres Near Lake Jordan
    $3,000,000
    33.48 Acres
    33 Acres Near Lake Jordan

    33 acres of land near Lake Jordan preservation lands.

    7571 Nc Hwy 751, Durham, NC 27713

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    Downtown Durham Retail Opportunity
    $830,000
    2,386 SF
    Downtown Durham Retail Opportunity

    2,386 SF retail property in prime downtown location.

    112 E MAIN ST, Durham, NC 27701

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    Downtown Durham Redevelopment Opportunity
    $1,000,000
    Downtown Durham Redevelopment Opportunity

    Mixed-use redevelopment opportunity in vibrant Downtown Durham on Main Street.

    113 West Main Street, Durham, NC 27701

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    Craftsman Live-Work Bungalow
    $499,500
    1,922 SF
    Craftsman Live-Work Bungalow

    A 1930s craftsman bungalow with flexible live/work layout and multiple interior rooms that can support office or institutional use.

    1814 Chapel Hill Road Unit 1814, Durham, NC 27707

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    High-Visibility Retail Storefront
    Contact for pricing
    2,904 SF
    High-Visibility Retail Storefront

    General Commercial property with prominent US 70 frontage and an accessory unit for flexible retail or service use.

    2104 US HWY 70 E, Durham, NC 27703

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    Prime Commercial Development Opportunity
    $1,375,000
    Prime Commercial Development Opportunity

    Zoned IP land near Imperial Center Business Park.

    5422 Page Road, Durham, NC 27703

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    Durham Restaurant with Drive-Thru
    $925,000
    2,088 SF
    Durham Restaurant with Drive-Thru

    Commercial building with drive-thru, ideal for restaurant or redevelopment.

    3203 N Roxboro, Durham, NC 27704

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    Established Durham Mechanical Shop For Sale
    $1,000,000
    4,000 SF
    Established Durham Mechanical Shop For Sale

    Income-producing mechanical shop with five service bays and ample parking.

    2410 Angier #B, Durham, NC 27703

    View details

    Research Triangle Park, NC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 138 commercial real estate for sale in Research Triangle Park, NC, showcased through 138 active listings on our real estate platform. These investment opportunities span a total of 240,209 square feet of properties for sale, with an estimated market value of $72,254,400.

    Sale prices for business properties in Research Triangle Park, NC start at $68,400, averaging $1,720,342, and reaching up to $6,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 5

    Listings Trend

    New vs delisted commercial listings in Durham County

    New Delisted

    Total CRE Inventory on Market (SF)

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