Research Triangle Park, NC Commercial Real Estate for Lease

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Found 138 commercial real estate listings for lease in Research Triangle Park, NC, averaging $33/SF/YR. Use lease type data to compare options faster.
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Cost-Efficient Office Space at RTP Meridian. Contact us today to book a tour!
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Fenced Specialty Property
Updated: Sep 28
Fenced Specialty Property

3417 S Alston Avenue, Durham, NC 27713

$3,500/Mo
1,920 sqft 0.39 AC lot
0.39‑acre fenced site
NC zoning
Built in 1978
Central heating and central air conditioning
Public water and public sewer
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Office Units with Shared Common Area
Updated: Jun 29
Office Units with Shared Common Area

3201 Yorktown Avenue, Durham, NC 27713

$350/Mo
907 sqft 1.55 AC lot
907 square feet of office space
Private office rooms with shared common area
24‑hour access
Wi‑Fi and utilities included
Located near the Research Triangle Park, Downtown Durham, and highways
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Multi-Suite Office Space
Multi-Suite Office Space

1906 N Carolina 54, Durham, NC 27713

$550/Mo
4–7 people  1,072 sqft  Built 1984  1.1 acres

Four office suites offer central heating and air conditioning, with shared cleaning and utility services included.

53 parking spaces
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Smart Workspace Options at NC, Durham - 3511 Shannon Road. Contact us today to book a tour!
Smart Workspace Options at NC, Durham - 3511 Shannon Road. Contact us today to book a tour!

3511 Shannon Rd, Durham, NC 27707

Coworking
$129-$11,196/Mo per office
1–13 people  16 spaces  11–2,082 sqft

Flexible workspace in NC, Durham - 3511 Shannon Road. Book a tour & get info

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Medical Office Space with Reception Area
Medical Office Space with Reception Area

2609 N Duke Street, Durham, NC 27704

$18 SF/Yr
2,312 sqft  Built 1978  0.01 acres
Highway access

Lease-ready medical office with private rooms, conference space, dedicated parking, and ADA-compliant restrooms.

Reception area  Private offices  Conference rooms  ADA-compliant restrooms
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First-Floor Office Unit
First-Floor Office Unit

1906 Nc-54, Durham, NC 27713

$22,523/Mo
4–7 people  1,072 sqft  Built 1984  1.02 acres
8 private offices  Highway access + Road access

The suite includes private offices, a conference area, shared work space, and a kitchenette.

58 parking spaces  Kitchenette
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Workspace Solutions at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!
Workspace Solutions at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!

555 S Mangum St, Unit 100, Durham, NC 27701

Coworking American Tobacco Campus
$129-$54,775/Mo per office
1–17 people  16 spaces  11–2,612 sqft

Find fully flexible work and meeting space in NC, Durham - Spaces Mangum Street. Book a tour & get info

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Business-Ready Workspace at RTP Imperial. Contact us today to book a tour!
Business-Ready Workspace at RTP Imperial. Contact us today to book a tour!

4819 Emperor Blvd, Unit 400, Durham, NC 27703

Coworking
$129-$13,893/Mo per office
1–13 people  16 spaces  11–1,965 sqft

Flexible workspace in RTP Imperial. Book a tour & get info

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First-Floor Office Unit
First-Floor Office Unit

3604 Shannon Road Ste 105, Durham, NC 27707

$900/Mo
8–14 people  2,115 sqft  Built 2006  Floor 1
6 private offices  1 meeting room  Highway access

Furnished professional suite with six private offices, conference room, kitchenette, and two restrooms.

Furnished
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Specialty Property
Specialty Property

3417 S Alston Avenue, Durham, NC 27713

$3,500/Mo
1,920 sqft  2,500 sqft building  Built 1978  0.4 acres

The NC-zoned property includes a commercial building on nearly 0.4 acres.

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Canterbury Hall Office Units
Canterbury Hall Office Units

4815 Emperor Blvd, Durham, NC 27703

$27.50 SF/Yr
10–17 people  2,682 sqft

Office availability at Canterbury Hall supports a range of space requirements in Durham.

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Carlisle Place Office Units
Carlisle Place Office Units

4721 Emperor Blvd, Durham, NC 27703

$29.50 SF/Yr
14–24 people  3,666 sqft

Lease opportunity for office users at a named commercial property in Durham.

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Oxford Place Office Units
Oxford Place Office Units

1005 Slater Rd, Durham, NC 27703

$27.50 SF/Yr
5–9 people  1,476 sqft

Lease opportunity for office accommodations at Oxford Place in Durham, North Carolina.

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Chelsea Place Office Units
Chelsea Place Office Units

1007 Slater Rd, Durham, NC 27703

$27.50 SF/Yr
5–9 people  1,494 sqft

Lease opportunities are available within a named office property in Durham.

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Standalone Flex Building
Standalone Flex Building

3821 Durham Chapel Hill Blvd, Durham, NC 27707

$23.11 SF/Yr
18,176 sqft  Built 1964

Available October 2027 with dedicated access and identity on a shared commercial parcel.

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Office Units
Office Units

4000 Sancar Way, Durham, NC 27713

$29.50 SF/Yr
5–8 people  1,332 sqft

Office space is available across a broad range of suite sizes.

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Corner Specialty Suite
Corner Specialty Suite

1858 Hillandale Road Ste 110, Durham, NC 27705

Omah Street
$3,400/Mo
1,728 sqft  Built 1997

Ste 110 corner suite located on Hillandale Road in Durham County, accessed via I-85 to Hillandale Rd.

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Renovated Historic Building in Durham
Renovated Historic Building in Durham

733 Foster St, Durham, NC 27701

Old North Durham
$26.95 SF/Yr
44–73 people  3 spaces  11,000 sqft

Turn-key, furnished office suites in walkable downtown location.

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Private-Office Coworking Space
Private-Office Coworking Space

3201 Yorktown Avenue Ste 117, Durham, NC 27713

Coworking
$350/Mo per office
3–6 people  907 sqft  Built 1988

Flexible workspace combines enclosed offices with shared common areas and round-the-clock access.

24 hour access  Wifi
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Erwin Road Mixed-Use Retail Space
Erwin Road Mixed-Use Retail Space

2812 & 2816 Erwin Rd, Durham, NC 27705

Duke West Campus
$25 SF/Yr
1,696 sqft

Class A retail space in mixed-use development near Duke University.

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Open-Plan Retail Suite
Open-Plan Retail Suite

4810 Hope Valley Road, Suite 107, Durham, NC 27707

Contact for pricing
Multi-tenant  2,652 sqft
18,480 VPD  Randy's Pizza, Wine & Design co-tenants  Highway access

Retail space with a private office, two restrooms, and ample parking in a mixed-use center.

Open floor plan  Private office  Two restrooms
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Professional Office Suite
Professional Office Suite

4210 N. Roxboro Street, Suite 140, Durham, NC 27704

$19 SF/Yr
1 space

Suite 140 supports professional services and medical office users within a maintained commercial center.

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Move-In Ready Office Building
Move-In Ready Office Building

313 Foster St, Durham, NC 27701

Central Park
Contact for pricing
16–27 people  4,125 sqft  Built 1930  2-story

Two-story office building with six offices, conference rooms, patio, and a rear loading dock plus three parking spaces.

3 parking spaces  Offices  Conference rooms  IT closet
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Flex Space with Showroom
Flex Space with Showroom

3220 Guess Road, Durham, NC 27705

Duke Homestead
Contact for pricing
6,864 sqft  3-phase  Built 1989
Highway access  Road access  Commercial Neighborhood

Glass retail frontage, warehouse storage, and a roll-up door create a versatile commercial configuration.

Multiple restrooms  Warehouse storage  Roll-up door  3 phase power
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Research Triangle Park, NC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Research Triangle Park, NC with 138 listings featured on our commercial real estate exchange. The current inventory includes 1,945,935 square feet of properties with an estimated lease value of $979.97.

Estimated lease rates for Commercial real estate in Research Triangle Park, NC begin at $4.63 SF/Yr, with an average of $32.67 SF/Yr and extend to $252.12 SF/Yr.

How to lease commercial real estate in Research Triangle Park, NC

  1. Define your requirements and budget. Pin down square footage, lease term, and a budget covering rent plus taxes, insurance, and maintenance.
  2. Pick the property type and submarket. Match office, retail, or industrial space to your needs and compare neighborhoods in Research Triangle Park, NC with Location Intelligence.
  3. Search through multiple channels. Combine listing platforms, driving your target area and networking to uncover off-market deals in Research Triangle Park, NC.
  4. Hire a tenant-rep broker. Landlords pay the commission, so a broker costs you nothing while unlocking better terms and hidden listings.
  5. Compare the true cost. Normalize offers to real occupancy cost with the Lease Calculator since base rent rarely tells the full story.
  6. Negotiate and review before signing. Push on free rent and TI allowances, then have an attorney review the lease before you sign.
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