Research Triangle Park, NC Commercial Real Estate for Lease

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135 properties
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Private Office Suite Space
Updated: Jun 29
Private Office Suite Space

3201 Yorktown Avenue, Durham, NC 27713

$350/Mo
907 sqft
Built in 1988
Private office rooms with shared common area
24‑hour access
WiFi and utilities included
Convenient location near RTP, Downtown, and highways
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Prime Medical Office Space Available
Updated: Dec 4, 2024
Prime Medical Office Space Available

2609 N Duke Street, Durham, NC 27704

$18 SF/Yr
2,312 sqft
Prime medical/office space in a highly sought‑after location on Durham's North Duke Street corridor.
Excellent visibility and easy access to major roads and highways.
Dedicated parking with ample spaces for clients and staff.
Versatile space ideal for medical, dental, or general office use.
Includes reception area, private offices, conference rooms, and ADA‑compliant restrooms.
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First-Floor Office Suite
First-Floor Office Suite

1906 Carolina 54, Durham, NC 27713

$45,045/Mo
2,145 sqft

First-floor office suite divisible into two smaller spaces with ample off-street parking and updated interior finishes.

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CG-Zoned Commercial Space
CG-Zoned Commercial Space

2810 Hillsborough Road, Durham, NC 27705

$18 SF/Yr
2,978 sqft

High-visibility commercial suite on Hillsborough Road with Commercial General zoning for a broad range of uses.

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Flex Space with Laydown Yard
Flex Space with Laydown Yard

2528 S Alston Avenue, Durham, NC 27713

$4,500/Mo
1,233 sqft

Industrial flex space with a small office setup, offering laydown yard and storage.

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Office Space in Stratford Hall
Office Space in Stratford Hall

1009 Slater Rd, Durham, NC 27703

$28.50 SF/Yr
1,800 sqft

Office suites within Stratford Hall are available for lease, offering multiple floor-area options.

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Second-Floor Office Suite
Second-Floor Office Suite

1910 Sedwick Rd, BLDG 500, Durham, NC 27713

$1,500/Mo
1,100 sqft

Second-floor office suites available in Building 500, offering approximately 1,100 SF each plus utilities.

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Corner Specialty Suite
Corner Specialty Suite

1858 Hillandale Road Ste 110, Durham, NC 27705

$3,400/Mo
1,728 sqft

Ste 110 corner suite located on Hillandale Road in Durham County, accessed via I-85 to Hillandale Rd.

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Roxboro Road Professional Office Space
Roxboro Road Professional Office Space

4210 N. Roxboro Street, Suite 140, Durham, NC 27704

$20.50 SF/Yr
2,408 sqft

Office space ideal for professional services and medical offices.

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Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!
Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!

555 Mangum St, Unit 100, Durham, NC 27701

16 available spaces from 11 to 2,612 sqft
$129-$54,775/Mo

Find fully flexible work and meeting space in NC, Durham - Spaces Mangum Street. Book a tour & get info

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Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!
Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!

4819 Emperor Blvd, Unit 400, Durham, NC 27703

16 available spaces from 11 to 1,965 sqft
$129-$13,893/Mo

Flexible workspace in RTP Imperial. Book a tour & get info

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Office Building Sublease Space
Office Building Sublease Space

505 S Duke St, Durham, NC 27701

Contact for pricing
4,897 sqft

Office space in the BB&T Building is available for sublease with 4,897 to 9,794 SF.

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First Floor Office Unit For Lease
First Floor Office Unit For Lease

100-a-1906 E Nc Highway 54, Durham, NC 27713

$45,045 SF/Yr
2,145 sqft

Flexible office unit with ample parking and high traffic count.

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Move-In Ready Office Building
Move-In Ready Office Building

313 Foster St, Durham, NC 27701

Contact for pricing
4,125 sqft

Two-story office building with six offices, conference rooms, patio, and a rear loading dock plus three parking spaces.

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Retail-Office Suite with Dedicated Parking
Retail-Office Suite with Dedicated Parking

600 Foster St, Durham, NC 27701

Contact for pricing
2,285 sqft

Short-term suite with flexible use options, finished concrete floors, high ceilings, natural light, and dedicated parking.

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Downtown Retail Space with Terrace
Downtown Retail Space with Terrace

500 East Main Street, Durham, NC 27701

$26 SF/Yr

Ground-floor retail in a 248-unit luxury apartment building with an outdoor dining terrace and structured customer parking.

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Luxury Mixed-Use Development Near Duke
Luxury Mixed-Use Development Near Duke

2812 & 2816 Erwin Rd |, Durham, NC 27705

$25 SF/Yr
118,000 sqft

Class A mixed-use development near Duke University and hospitals.

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Industrial Warehouse for Lease
Industrial Warehouse for Lease

1111 Neville Street, Durham, NC 27701

Contact for pricing
3,360 sqft

Industrial warehouse space suited for storage, warehousing, or light distribution near downtown access.

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Industrial Warehouse Space
Industrial Warehouse Space

1111 Neville St, Durham, NC 27701

Contact for pricing
3,360 sqft

Warehouse space for storage, warehousing, or light distribution near downtown Durham and major transportation routes.

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Office Suites for Lease
Office Suites for Lease

112 S Duke St, Durham, NC 27701

Contact for pricing
1,349 sqft

Multiple office unit sizes are available for lease at Peabody Place.

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Downtown Office Suites
Downtown Office Suites

905 W Main St, Durham, NC 27701

Contact for pricing
918 sqft

Office suites are available for lease at 905 W Main St in Durham, with space ranging from 918 to 21,918 SF.

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Office Suite Sublease Opportunity
Office Suite Sublease Opportunity

2645 Meridian Pkwy, Durham, NC 27713

Contact for pricing
2,166 sqft

Sublease office space is available at 2645 Meridian Pkwy in Durham, with 2,870 square feet of rentable area.

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Downtown Durham Retail Space Available
Downtown Durham Retail Space Available

400 West Main Street, Durham, NC 27701

Contact for pricing
12,473 sqft

Prime retail spaces in a vibrant downtown location.

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Office Space in Durham
Office Space in Durham

324 Blackwell Street, Durham, NC 27701

$29.95 SF/Yr
9,778 sqft

Office space available for lease in Durham, North Carolina.

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Research Triangle Park, NC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Research Triangle Park, NC with 135 listings featured on our commercial real estate exchange. The current inventory includes 372,660 square feet of properties with an estimated lease value of $1,107 /Mo.

Estimated lease rates for Commercial real estate in Research Triangle Park, NC begin at $4.63 SF/Yr, with an average of $52.72 SF/Yr and extend to $252 SF/Yr.
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