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Desoto County, MS Commercial Real Estate for Sale

310 results
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Olive Branch Commercial Site For Sale
$210,000
3,400 SF

Olive Branch Commercial Site For Sale

8205 Highway 178, Olive Branch, MS 38654

Commercial site with existing building, suitable for various business uses.

  • Prime commercial location at the southeast corner of Hwy 178 and Maywood Drive.
  • Existing 3,400 sf building with roll‑up door and canopy.
  • All utilities are available on site.
  • Fenced portion of the lot around the building and canopy.
  • Suitable for various businesses such as automobile repair, tire shop, or produce stand.
Updated: Oct 20, 2025
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Versatile Commercial Building in Southaven
$425,000
3,754 SF

Versatile Commercial Building in Southaven

1310 E Goodman Rd, Southaven, MS 38671

Multi-purpose building with studio, offices, and flex space.

  • Large 3754 sq ft multi‑purpose building
  • Includes a 700 sq ft studio with mirrors and hardwood floor
  • Multiple entrances allow for multiple private offices
  • Additional private office with two open rooms and private bathroom
  • Located in a growing area close to shopping, restaurants, and residential areas
Updated: Oct 13, 2025
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Southaven Commercial Property For Sale
Pending
$999,990
5,000 SF

Southaven Commercial Property For Sale

Two office buildings on 1.2 acres in high-demand area.

5185 Getwell Rd, Southaven, MS 38672
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Former Bank Building on Goodman
$799,000
2,786 SF

Former Bank Building on Goodman

2786 SF commercial building with drive-thru and ample parking.

2304 Goodman Rd, Horn Lake, MS 38637
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Southaven Commercial Property For Sale
$160,000
1,100 SF

Southaven Commercial Property For Sale

Commercial property with potential for various uses in Southaven, MS.

55 E Stateline Rd, Southaven, MS 38671
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Modern Gas Station and Store
$3,500,000
5,570 SF

Modern Gas Station and Store

High-performing gas station and convenience store in Olive Branch, MS.

7641 Hacks Cross Rd, Olive Branch, MS 38654
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Veterinary Practice in Growing Area
$990,000

Veterinary Practice in Growing Area

Successful veterinary practice for sale in rapidly growing North Mississippi.

5165 Getwell Rd, Southaven, MS 38671
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Established Car Wash Business Opportunity
$250,000
1,840 SF

Established Car Wash Business Opportunity

Turnkey car wash business in a strategic, growing area.

1999 Highway 301 S, Lake Cormorant, MS 38641
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Hernando Commercial Automotive Business Opportunity
$440,000
1,800 SF

Hernando Commercial Automotive Business Opportunity

Established automotive business with shop, office, and included equipment.

310 E St S, Hernando, MS 38632
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Established Car Wash Business Opportunity
$550,000
3,663 SF

Established Car Wash Business Opportunity

Turnkey car wash business in prime location near Hernando square.

2934 Highway 51 S, Hernando, MS 38632
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Southaven Commercial Land Opportunity
$299,900
41,382 SF

Southaven Commercial Land Opportunity

Prime 0.95-acre lot, ideal for development.

10 Airways Blvd, Southaven, MS 38671
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High-Visibility Retail Lot, Southaven
$650,000
43,125 SF

High-Visibility Retail Lot, Southaven

Prime I-55 location, high traffic count.

420 Church Rd Rd, Southaven, MS 38671
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Highly Successful Vet Practice For Sale
$990,000

Highly Successful Vet Practice For Sale

Prime Southaven Location, High Growth Area

5165 Getwell Rd, Southaven, MS 38671
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Hernando Office Building - Prime Location
$600,000
2,371 SF

Hernando Office Building - Prime Location

Historic Charm, Modern Potential, High Visibility

2475 Memphis St, Hernando, MS 38632
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Hilton Garden Inn Olive Branch
Contact for pricing
3.98 Acres

Hilton Garden Inn Olive Branch

121-Room Hotel, Memphis Submarket

7890 Craft-Goodman Rd, Olive Branch, MS 38654
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High-Demand Truck Stop & C-Store
$5,495,000

High-Demand Truck Stop & C-Store

Olive Branch, MS - Exceptional Investment Opportunity

7532 Hacks Cross Rd, Olive Branch, MS 38654
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Prime Olive Branch Retail Land
$900,000

Prime Olive Branch Retail Land

High-traffic QSR/Restaurant Site

7575 Goodman Rd, Olive Branch, MS 38654
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Church Road Shopping Center
$3,750,000
12,000 SF

Church Road Shopping Center

High-Yield Retail Investment in Olive Branch, MS

5025 Church Road Ext, Olive Branch, MS 38654
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Luxury Olive Branch Hotel Investment
Contact for pricing
3.97 Acres

Luxury Olive Branch Hotel Investment

95-Room Marriott Suites Hotel in MS

7840 Craft-Goodman Rd, Olive Branch, MS 38654
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Horn Lake Medical Investment Opportunity
$3,709,593
4,503 SF

Horn Lake Medical Investment Opportunity

NNN leased medical office in growing Memphis suburb.

4033 Fountain Ln, Horn Lake, MS
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NN Investment Property with Options
$3,679,090
11,945 SF

NN Investment Property with Options

Long-term investment opportunity with drive-thru and extension options.

6040 Goodman Rd, Walls, MS 38680
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Mid South Center Shopping Center
$4,342,778
42,130 SF

Mid South Center Shopping Center

42,130 SF shopping center with 97% occupancy.

6219 Highway 305 N, Olive Branch, MS 38654
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Retail Property in Growing Olive Branch
$3,041,354
10,640 SF

Retail Property in Growing Olive Branch

Retail property located in a fast-growing area near industrial parks.

14800 Goodman Rd, Olive Branch, MS 38654
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Olive Branch Warehouse with Rail
Contact for pricing
95,000 SF

Olive Branch Warehouse with Rail

95,000 SF warehouse with rail access and heavy power.

10633 High Point Rd, Olive Branch, MS 38654
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Desoto County, MS Commercial Real Estate Investment Opportunities Market Analysis

Explore 1790 commercial real estate investment opportunities in Desoto County, MS with 310 listings featured on our commercial real estate marketplace. The current inventory includes 268,223,492 square feet of properties with an estimated value of $766,192,396.

Estimated prices for commercial real estate in Desoto County, MS begin at $48,000, with an average of $595,332 and extend to $8,900,000.

In Desoto County, MS, current investment values show:

  • Other commercial real estate positioned at $649,961
  • Retail properties measuring $583,488
  • Land assessed at $537,075
  • Office Properties & Spaces calculated at $529,508
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