West Plains, MO Commercial real estate for sale

Updated: Sep 21

Mixed-Use Barndominium

6475 Private Road 1182, West Plains, MO 65775

$999,000

4.00 AC lot

4‑acre mixed‑use property with residential and commercial components
Two finished 1,000 square foot commercial spaces with separate entrances
Each commercial space includes its own half bathroom
Two‑story 80'x80' barndominium completed in 2024
Attached 40'x40' garage with 18' ceiling and concrete apron

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Updated: Sep 16

Highway-Front Restaurant Property

210 Jan Howard Expressway, West Plains, MO 65775

$499,900

0.60 AC lot

Approximately 2,000 sq. ft. commercial building on 0.6 acres
Frontage along US Highway 63 at 210 Jan Howard Expressway
Paved parking for approximately 26 vehicles
Updated interior with custom cabinetry and epoxy countertops
Multiple access points and two bathrooms

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Restaurant with Entertainment Space

5024 Us Highway 160, West Plains, MO 65775

$799,900

13.80 AC lot

A commercial kitchen, bar, event rooms and virtual golf stalls serve the existing restaurant and entertainment setup.

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Acreage Property with Workshop

11553 County Road 7070, West Plains, MO 65775

$799,900

2,263 sqft

A 2024 home with geothermal heating and cooling, extensive covered patios, and a detached shop with RV hookup.

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Mixed-Use Property with Residence

4828 Us Highway 160, West Plains, MO 65775

$319,900

2.50 AC lot

Highway-frontage property combines a shell commercial building with a detached residence, garage, and mobile home hookup.

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Steel Flex Space with Living Quarters

6167 Us-63, West Plains, MO 65775

$1,889,000

26.40 AC lot

Highway-fronted commercial property with offices, climate-controlled workspace, utility infrastructure, and additional land for operational flexibility.

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Two-Unit Warehouse with Loading Dock

1641/1643 Good Hard Drive, West Plains, MO 65775

$595,900

2.93 AC lot

Commercial warehouse property with divided operating areas, truck maneuverability, and Highway 63 access.

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Ranch with Barn

8896 State Route Zz, West Plains, MO 65775

$650,000

3,452 sqft

A single-level home, livestock pens, and a large utility barn support a working acreage property.

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Convenience Store with Fast-Food Tenant

312 Porter Wagoner Boulevard, West Plains, MO 65775

$750,000

0.59 AC lot

Convenience store building with an existing fast-food tenant and room for expansion.

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Mixed-Use Building with Apartment

313 Washington Avenue, West Plains, MO 65775

$355,000

0.05 AC lot

Two kitchens, private parking, and street-level commercial space support flexible live-work use.

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Farm with Remodeled Residence

1201 East US Highway 160, West Plains, MO 65775

$850,000

60 sqft

Ozarks acreage includes extensive farm improvements, pasture, ponds, and a separate guest or rental dwelling.

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Warehouse with Loading Docks

4428 County Road 4660, West Plains, MO 65775

$1,700,000

2.21 AC lot

Flexible warehouse layout includes office areas, customer-facing space, storage, loading access, and amenities for varied commercial operations.

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Multi-Section Flex Space

1015 Preacher Roe Boulevard, West Plains, MO 65775

$546,000

1.50 AC lot

Adaptable commercial facility with separate service areas, loading access, fenced storage yards, and office-style frontage.

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Two-Unit Warehouse Building

1641 Goodhard Drive, West Plains, MO 65775

Contact for pricing

3,900 sqft 2.93 AC lot

Divided warehouse layout with individual restrooms and heating and cooling.

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Office Building With Warehouse

902 S Hill Street, West Plains, MO 65775

$199,900

0.23 AC lot

Two-building commercial property with office space, a separate shop, and street frontage on both improvements.

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Mixed-Use Property with Highway Frontage

4828 HWY 160, West Plains, MO 65775

$319,900

2.50 AC lot

Includes a three-bedroom residence, three-car garage, and commercial shell on a multi-acre parcel.

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COMMERCIAL/INDUSTRIAL, West Plains, MO

4828 Us Highway 160, West Plains, MO 65775

$319,900

2.50 AC lot

Includes a three-bedroom residence, three-car garage, and commercial shell on a multi-acre parcel.

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Highway Frontage Commercial Land

1753 Private Road 8650, West Plains, MO 65775

$115,900

4.48 AC lot

Vacant commercial land with highway frontage and electricity available.

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Commercial Sale, West Plains, MO

4828 Us Highway 160, West Plains, MO 65775

$319,900

2.50 AC lot

Highway-frontage property combines a shell commercial building with a detached residence, garage, and mobile home hookup.

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Corner Convenience Store

804 Saint Louis Street, West Plains, MO 65775

$159,000

0.27 AC lot

Open layout with industrial kitchen, storage, office space, and two bathrooms.

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Ozarks Farmland and Hunting Land

000 County Road 8820, West Plains, MO 65775

$843,900

145.50 AC lot

Extensive acreage with open pasture, wooded areas, three ponds, and multiple building sites, including hay and crop potential.

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Automotive Property with Office

959 Preacher Roe Boulevard, West Plains, MO 65775

$169,000

0.60 AC lot

The site includes chip-sealed parking and two property accesses.

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Working Farm with Off-Grid Cabin

1420 State Route 14, West Plains, MO 65775

$299,000

576 sqft

Fenced pasture, two ponds, and an off-grid cabin support on-site agricultural use.

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Flex Space with Living Quarters

4359 Us Highway 160, West Plains, MO 65775

$215,000

0.50 AC lot

Mixed-use configuration combines open commercial space with finished living quarters.

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West Plains, MO Commercial Real Estate Market Trends and Statistics

Explore 156 commercial real estate for sale in West Plains, MO, showcased through 156 active listings on our real estate platform. These investment opportunities span a total of 15,820 square feet of properties for sale, with an estimated market value of $103,016,700.

Sale prices for business properties in West Plains, MO start at $40,000, averaging $780,429, and reaching up to $4,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
65775	$677.3K

Neighborhood

Average Price

65775

$677.3K

Featured West Plains Real Estate Agencies

Realmo connects you with licensed West Plains CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Westgate Realty, Inc.

74D North Kentucky Ave. West Plains, MO

Phone: (417) 257-2733

shaundugginsgroup.com

37 North Realty Group - West Plains

1704 N Kentucky Ave, Suite 2 West Plains, MO 65775

Phone: (417) 258-8001

www.37northrealty.com

Iron Brand Realty, LLC

804 Porter Wagoner Blvd. West Plains, MO

Phone: (417) 372-8076

ironbrandrealty.com