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    Mississippi County, MO Commercial Real Estate for Sale

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    Saint Louis, MO Kansas City, MO Louis, MO
    12 results
    East Prairie Commercial Building For Sale
    $185,000
    9,700 SF

    East Prairie Commercial Building For Sale

    201-203 E. Pine, East Prairie, MO 63845

    9700 sqft commercial building in East Prairie, Missouri.

    • Priced below last appraised value
    • Excellent location close to downtown East Prairie
    • 9700 square foot building suitable for retail or office use
    • 8‑10 overhead doors for deliveries or loading
    • Ample parking for approximately 20 cars
    Updated: Dec 15, 2025
    View details
    Remodeled Commercial Property in Charleston
    $350,000
    4,173 SF

    Remodeled Commercial Property in Charleston

    506 S Main Street, Charleston, MO 63834

    Turnkey commercial property with residential zoning in prime location.

    • Prime location with high visibility.
    • Turnkey, beautifully remodeled commercial property.
    • Zoned for commercial/residential use.
    • Substantial 4173 Sq Ft of space.
    • New roof, windows, flooring, and bathrooms.
    Updated: Jan 23
    View details
    Charleston, MO Commercial Land Opportunity
    $950,000
    11.04 Acres

    Charleston, MO Commercial Land Opportunity

    11.04 acre commercial land with high visibility and access.

    3,5,7,9 Charleston Plaza, Charleston, MO 63834
    View details
    Productive Farm in Bertrand, Missouri
    $1,100,000
    230.00 Acres

    Productive Farm in Bertrand, Missouri

    230-acre farm with income potential and expansion opportunities.

    000 County Road 429, Bertrand, MO 63823
    View details
    Charleston Commercial Property on Highway
    $110,000
    2,121 SF

    Charleston Commercial Property on Highway

    Commercial property with existing building and highway frontage in Charleston.

    1113 E. Marshall, Charleston, MO 63834
    View details
    Remodeled Mixed-Use Property For Sale
    $425,000
    4,173 SF

    Remodeled Mixed-Use Property For Sale

    Turnkey, remodeled mixed-use property with commercial/residential zoning.

    506 S Main Street, Charleston, MO 63834
    View details
    Farmland in Desirable Farming Area
    $655,000

    Farmland in Desirable Farming Area

    66.23 acres of farmland perfect for agricultural use.

    Hwy 60, Wyatt, MO 63882
    View details
    RV Park with Restaurant
    $740,000
    3,876 SF

    RV Park with Restaurant

    RV park with restaurant, store, cabins, and highway frontage.

    4067 W. 404 Road, Bertrand, MO 63823
    View details
    Retail Building on Highway 105
    $84,000
    1,452 SF

    Retail Building on Highway 105

    Retail building with great visibility and expansion potential.

    2380 S. Main, Charleston, MO 63834
    View details
    17-Acre Parcel Near Dogwood Community
    $260,000
    17.00 Acres

    17-Acre Parcel Near Dogwood Community

    17-acre parcel with tillable land and rental properties.

    2447 West 416th Road, East Prairie, MO 63845
    View details
    Charleston, MO Commercial Investment Opportunity
    $575,000
    2,134 SF

    Charleston, MO Commercial Investment Opportunity

    High-traffic commercial property suitable for restaurant, retail, or office use.

    11 Truman St, Charleston, MO 63834
    View details
    478 Acres Excellent Soybean Land
    $4,541,000
    478.00 Acres

    478 Acres Excellent Soybean Land

    478 acres of soybean land, suitable for duck hunting.

    East Prairie, MO 63845
    View details
    Based on your search, we've compiled 587 Potential Opportunities for your consideration. Besides 12 Active listings in Mississippi County, MO, we suggest exploring several alternatives: similar 575 Off-Market properties to explore as potential leads

    Explore Off-Market Properties in Mississippi County, MO

    Consider similar Off-Market properties in Mississippi County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    102 Garfield St

    102 Garfield St

    COMMERCIAL (GENERAL) • 0.88 Acres
    Value Estimation by Request
    102 Garfield St, East Prairie, MO 63845-1556
    View details
    115 Main St

    115 Main St

    OFFICE (GENERAL) • 4,453 SF
    Value Estimation by Request
    115 Main St, Charleston, MO 63834-1632
    View details
    203 Washington St

    203 Washington St

    RETAIL STORES (PERSONAL SERVICES) • 2,173 SF
    Value Estimation by Request
    203 Washington St, East Prairie, MO 63845-1527
    View details
    Aly Behind 606th Helena

    Aly Behind 606th Helena

    WAREHOUSE, STORAGE • 1,571 SF
    Value Estimation by Request
    Aly Behind 606th Helena, Charleston, MO 63834
    View details
    801 Marshall St

    801 Marshall St

    OFFICE (GENERAL) • 7,032 SF
    Value Estimation by Request
    801 Marshall St, Charleston, MO 63834-1262
    View details
    204 1st St

    204 1st St

    OFFICE (GENERAL) • 1,664 SF
    Value Estimation by Request
    204 1st St, Charleston, MO 63834-1100
    View details
    105 Ctr St

    105 Ctr St

    RETAIL STORES (PERSONAL SERVICES) • 1,612 SF
    Value Estimation by Request
    105 Ctr St, Charleston, MO 63834-1602
    View details
    208 Commercial St

    208 Commercial St

    OFFICE (GENERAL) • 2,150 SF
    Value Estimation by Request
    208 Commercial St, Charleston, MO 63834-1749
    View details
    Garfield

    Garfield

    CAR WASH • 2,478 SF
    Value Estimation by Request
    Garfield, East Prairie, MO 63845
    View details
    201 Ctr St

    201 Ctr St

    FUNERAL HOME • 5,588 SF
    Value Estimation by Request
    201 Ctr St, Charleston, MO 63834-1604
    View details
    931 Main St

    931 Main St

    SERVICE STATION (FULL SERVICE) • 1,305 SF
    Value Estimation by Request
    931 Main St, East Prairie, MO 63845-8133
    View details
    121 Pne St

    121 Pne St

    RETAIL STORES (PERSONAL SERVICES) • 1,686 SF
    Value Estimation by Request
    121 Pne St, East Prairie, MO 63845-1137
    View details

    Mississippi County, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 587 commercial real estate for sale in Mississippi County, MO, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 27,629 square feet of properties for sale, with an estimated market value of $2,469,000.

    Sale prices for business properties in Mississippi County, MO start at $84,000, averaging $352,714, and reaching up to $740,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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