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    Mississippi County, MO Office Spaces for Sale

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    Kansas City, MO Louis, MO Saint Louis, MO
    East Prairie Commercial Building For Sale
    $185,000
    9,700 SF
    East Prairie Commercial Building For Sale

    201-203 E. Pine, East Prairie, MO 63845

    9700 sqft commercial building in East Prairie, Missouri.
    • Priced below last appraised value
    • Excellent location close to downtown East Prairie
    • 9700 square foot building suitable for retail or office use
    • 8‑10 overhead doors for deliveries or loading
    • Ample parking for approximately 20 cars
    Updated: Dec 15, 2025
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    Charleston, MO Commercial Investment Opportunity
    $575,000
    2,134 SF
    Charleston, MO Commercial Investment Opportunity

    11 Truman St, Charleston, MO 63834

    High-traffic commercial property suitable for restaurant, retail, or office use.
    • Prime location at the intersection of I‑57 and US Hwy 62, offering high visibility and accessibility.
    • Currently operating as a fully equipped, turnkey restaurant, ideal for immediate use or adaptation.
    • High‑traffic location ensures maximum exposure to local and passing customers.
    • Adaptable 2,134 square foot commercial space suitable for various business types.
    • Strategic location with easy access to major highways and proximity to residential and commercial areas.
    Updated: Mar 11, 2025
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    High-Frontage Retail or Office Building
    $99,900
    2,121 SF
    High-Frontage Retail or Office Building

    Commercial building on a highway-frontage site with space for retail or office redevelopment.

    1113 E. Marshall, Charleston, MO 63834

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 3 Active listings in Mississippi County, MO, we suggest exploring several alternatives: similar 69 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Ready For Development
    $199,000
    2.00 Acres
    Commercial Land Ready For Development

    Two-acre commercial lot available for development in Sikeston, Missouri.

    224 S Interstate Drive, Sikeston, MO 63801

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    Commercial Land in Sikeston, MO
    $195,000
    0.72 Acres
    Commercial Land in Sikeston, MO

    Vacant, level commercial lot available in Sikeston, Missouri.

    116 Hospitality Drive, Sikeston, MO 63801

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    Commercial Land on Highway 61
    $144,000
    1.01 Acres
    Commercial Land on Highway 61

    Commercial land on high-traffic route near Sikeston Industrial Park.

    103 Grove Estates, Sikeston, MO 63801

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    Cape Girardeau Commercial Land Opportunity
    $389,000
    10.20 Acres
    Cape Girardeau Commercial Land Opportunity

    7.5-acre commercial lot in prime Cape Girardeau location.

    0 Rear Commercial Street, Cape Girardeau, MO 63703

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    Off-Market Properties in Mississippi County, MO

    Consider similar Off-Market properties in Mississippi County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    115 Main St
    OFFICE (GENERAL)
    4,453 SF Lot: 0.39 Acres
    Value Estimation by Request

    115 Main St, Charleston, MO 63834-1632

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    801 Marshall St
    OFFICE (GENERAL)
    7,032 SF Lot: 0.33 Acres
    Value Estimation by Request

    801 Marshall St, Charleston, MO 63834-1262

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    204 1st St
    OFFICE (GENERAL)
    1,664 SF Lot: 0.10 Acres
    Value Estimation by Request

    204 1st St, Charleston, MO 63834-1100

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    208 Commercial St
    OFFICE (GENERAL)
    2,150 SF Lot: 0.16 Acres
    Value Estimation by Request

    208 Commercial St, Charleston, MO 63834-1749

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    109 Commercial St
    OFFICE (GENERAL)
    520 SF Lot: 0.02 Acres
    Value Estimation by Request

    109 Commercial St, Charleston, MO 63834-1728

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    2402 Main St
    MEDICAL BUILDING
    7,833 SF Lot: 1.51 Acres
    Value Estimation by Request

    2402 Main St, Charleston, MO 63834-8318

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    3343 Hwy 80
    OFFICE (GENERAL)
    614 SF Lot: 13.60 Acres
    Value Estimation by Request

    3343 Hwy 80, East Prairie, MO 63845-9194

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    3980 Hwy 80
    OFFICE (GENERAL)
    907 SF Lot: 0.52 Acres
    Value Estimation by Request

    3980 Hwy 80, East Prairie, MO 63845-8972

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    208 Main St
    OFFICE (GENERAL)
    2,137 SF Lot: 0.23 Acres
    Value Estimation by Request

    208 Main St, Charleston, MO 63834-1640

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    307 Main St
    OFFICE (GENERAL)
    1,165 SF Lot: 0.15 Acres
    Value Estimation by Request

    307 Main St, East Prairie, MO 63845-1125

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    831 Hwy 105
    OFFICE (GENERAL)
    4,698 SF Lot: 3.00 Acres
    Value Estimation by Request

    831 Hwy 105, Charleston, MO 63834-8371

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    1300 Plant Rd
    OFFICE (GENERAL)
    8,338 SF Lot: 19.34 Acres
    Value Estimation by Request

    1300 Plant Rd, Charleston, MO 63834-2375

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    905 Main St
    OFFICE (GENERAL)
    1,920 SF Lot: 2.04 Acres
    Value Estimation by Request

    905 Main St, East Prairie, MO 63845-8133

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    219 Main St
    OFFICE (GENERAL)
    2,878 SF Lot: 0.08 Acres
    Value Estimation by Request

    219 Main St, East Prairie, MO 63845-1123

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    625 Washington St
    OFFICE (GENERAL)
    1,133 SF
    Value Estimation by Request

    625 Washington St, East Prairie, MO 63845-1823

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    1110 Marshall St
    OFFICE (GENERAL)
    2,688 SF Lot: 1.44 Acres
    Value Estimation by Request

    1110 Marshall St, Charleston, MO 63834-1353

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    County Rd 326-barnsgbs
    OFFICE (GENERAL)
    672 SF Lot: 2.38 Acres
    Value Estimation by Request

    County Rd 326-barnsgbs, Charleston, MO 63834

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    400 Main St
    MEDICAL BUILDING
    3,215 SF Lot: 0.17 Acres
    Value Estimation by Request

    400 Main St, Charleston, MO 63834-1644

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    913 Washington St
    OFFICE (GENERAL)
    2,514 SF Lot: 0.90 Acres
    Value Estimation by Request

    913 Washington St, East Prairie, MO 63845-1052

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    405 407th E Main-offic
    OFFICE (GENERAL)
    1,298 SF
    Value Estimation by Request

    405 407th E Main-offic, East Prairie, MO 63845

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    611 633rd S Hwy
    OFFICE (GENERAL)
    973 SF Lot: 4.00 Acres
    Value Estimation by Request

    611 633rd S Hwy, East Prairie, MO 63845

    View details

    Mississippi County, MO Office Spaces Investment Opportunities Market Analysis

    Explore 72 office spaces for sale in Mississippi County, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 13,955 square feet of properties for sale, with an estimated market value of $870,000.

    Sale prices for office spaces in Mississippi County, MO start at $110,000, averaging $290,000, and reaching up to $575,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Office Spaces by market

    Browse Office Spaces for Sale Near Mississippi, MO

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