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    Mississippi County, MO Office Properties & Spaces for Sale

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    Saint Louis, MO Kansas City, MO Louis, MO
    East Prairie Commercial Building For Sale
    $185,000
    9,700 SF

    East Prairie Commercial Building For Sale

    201-203 E. Pine, East Prairie, MO 63845

    9700 sqft commercial building in East Prairie, Missouri.

    • Priced below last appraised value
    • Excellent location close to downtown East Prairie
    • 9700 square foot building suitable for retail or office use
    • 8‑10 overhead doors for deliveries or loading
    • Ample parking for approximately 20 cars
    Updated: Dec 15, 2025
    View details
    Charleston Commercial Property on Highway
    $110,000
    2,121 SF

    Charleston Commercial Property on Highway

    1113 E. Marshall, Charleston, MO 63834

    Commercial property with existing building and highway frontage in Charleston.

    • Excellent traffic exposure with over 300' of highway frontage.
    • Prime commercial location, just 1 mile from I‑57.
    • Existing building with over 2100 square feet of space.
    • 2+ acres of land offering additional space and commercial potential.
    • Suitable for retail or office space after renovation.
    Updated: Apr 10, 2025
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    Charleston, MO Commercial Investment Opportunity
    $575,000
    2,134 SF

    Charleston, MO Commercial Investment Opportunity

    High-traffic commercial property suitable for restaurant, retail, or office use.

    11 Truman St, Charleston, MO 63834
    View details
    Based on your search, we've compiled 108 Potential Opportunities for your consideration. Besides 3 Active listings in Mississippi County, MO, we suggest exploring several alternatives: similar 101 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Renovated Commercial Building in Cape Girardeau
    $239,900
    2,937 SF

    Renovated Commercial Building in Cape Girardeau

    Renovated commercial building with high visibility in a prime location.

    230 N Sprigg Street, Cape Girardeau, MO 63701
    View details
    Commercial Land in Dexter, MO
    $2,000,000
    2.96 Acres

    Commercial Land in Dexter, MO

    Commercial property suitable for business, subdivision possible.

    0 W Bus Hwy 60, Dexter, MO 63841
    View details
    Fulton Commercial Development Site
    $1,150,000
    33.60 Acres

    Fulton Commercial Development Site

    33-acre commercial development site in Fulton, KY, near I-69.

    Myatt Road, Fulton, KY 42041
    View details
    Union City Building Lots
    Contact for pricing

    Union City Building Lots

    Land for sale in Union City, Tennessee.

    604 Miles Avenue N (Lot 5), Union City, TN 38261
    View details

    Explore Off-Market Properties in Mississippi County, MO

    Consider similar Off-Market properties in Mississippi County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    115 Main St

    115 Main St

    OFFICE (GENERAL) • 4,453 SF
    Value Estimation by Request
    115 Main St, Charleston, MO 63834-1632
    View details
    801 Marshall St

    801 Marshall St

    OFFICE (GENERAL) • 7,032 SF
    Value Estimation by Request
    801 Marshall St, Charleston, MO 63834-1262
    View details
    204 1st St

    204 1st St

    OFFICE (GENERAL) • 1,664 SF
    Value Estimation by Request
    204 1st St, Charleston, MO 63834-1100
    View details
    208 Commercial St

    208 Commercial St

    OFFICE (GENERAL) • 2,150 SF
    Value Estimation by Request
    208 Commercial St, Charleston, MO 63834-1749
    View details
    109 Commercial St

    109 Commercial St

    OFFICE (GENERAL) • 520 SF
    Value Estimation by Request
    109 Commercial St, Charleston, MO 63834-1728
    View details
    2402 Main St

    2402 Main St

    MEDICAL BUILDING • 7,833 SF
    Value Estimation by Request
    2402 Main St, Charleston, MO 63834-8318
    View details
    3343 Hwy 80

    3343 Hwy 80

    OFFICE (GENERAL) • 614 SF
    Value Estimation by Request
    3343 Hwy 80, East Prairie, MO 63845-9194
    View details
    3980 Hwy 80

    3980 Hwy 80

    OFFICE (GENERAL) • 907 SF
    Value Estimation by Request
    3980 Hwy 80, East Prairie, MO 63845-8972
    View details
    208 Main St

    208 Main St

    OFFICE (GENERAL) • 2,137 SF
    Value Estimation by Request
    208 Main St, Charleston, MO 63834-1640
    View details
    307 Main St

    307 Main St

    OFFICE (GENERAL) • 1,165 SF
    Value Estimation by Request
    307 Main St, East Prairie, MO 63845-1125
    View details
    831 Hwy 105

    831 Hwy 105

    OFFICE (GENERAL) • 4,698 SF
    Value Estimation by Request
    831 Hwy 105, Charleston, MO 63834-8371
    View details
    1300 Plant Rd

    1300 Plant Rd

    OFFICE (GENERAL) • 8,338 SF
    Value Estimation by Request
    1300 Plant Rd, Charleston, MO 63834-2375
    View details
    905 Main St

    905 Main St

    OFFICE (GENERAL) • 1,920 SF
    Value Estimation by Request
    905 Main St, East Prairie, MO 63845-8133
    View details
    219 Main St

    219 Main St

    OFFICE (GENERAL) • 2,878 SF
    Value Estimation by Request
    219 Main St, East Prairie, MO 63845-1123
    View details
    625 Washington St

    625 Washington St

    OFFICE (GENERAL) • 1,133 SF
    Value Estimation by Request
    625 Washington St, East Prairie, MO 63845-1823
    View details
    1110 Marshall St

    1110 Marshall St

    OFFICE (GENERAL) • 2,688 SF
    Value Estimation by Request
    1110 Marshall St, Charleston, MO 63834-1353
    View details
    County Rd 326-barnsgbs

    County Rd 326-barnsgbs

    OFFICE (GENERAL) • 672 SF
    Value Estimation by Request
    County Rd 326-barnsgbs, Charleston, MO 63834
    View details
    400 Main St

    400 Main St

    MEDICAL BUILDING • 3,215 SF
    Value Estimation by Request
    400 Main St, Charleston, MO 63834-1644
    View details
    913 Washington St

    913 Washington St

    OFFICE (GENERAL) • 2,514 SF
    Value Estimation by Request
    913 Washington St, East Prairie, MO 63845-1052
    View details
    405 407th E Main-offic

    405 407th E Main-offic

    OFFICE (GENERAL) • 1,298 SF
    Value Estimation by Request
    405 407th E Main-offic, East Prairie, MO 63845
    View details
    611 633rd S Hwy

    611 633rd S Hwy

    OFFICE (GENERAL) • 973 SF
    Value Estimation by Request
    611 633rd S Hwy, East Prairie, MO 63845
    View details

    Mississippi County, MO Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 104 office properties & spaces for sale in Mississippi County, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 31,263,636 square feet of properties for sale, with an estimated market value of $14,900,000.

    Sale prices for office spaces in Mississippi County, MO start at $110,000, averaging $551,851, and reaching up to $865,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Mississippi, MO

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