East Prairie, MO Commercial real estate for sale

Updated: Jul 30

Restaurant Building with Storage

115 East Pine Street, East Prairie, MO 63845

$300,000

1,600 sqft 0.31 AC lot

Restaurant equipment and supplies convey with the property
Two additional storage buildings and a generator included
0.3058‑acre site with on‑site parking
Commercial zoning in East Prairie, MO
Built in 2003 with central air conditioning

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Updated: Dec 15, 2025

Brick Flex Building with Loading

201-203 E. Pine, East Prairie, MO 63845

$185,000

9,700 sqft 0.44 AC lot

9,700‑square‑foot brick building constructed in 1972
0.44‑acre corner lot at 201‑203 E. Pine in East Prairie
Interior area measures 68'-72' with 10' ceilings
8‑10 overhead doors for deliveries or loading
Approximately 20 parking spaces

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 2 Active listings in East Prairie, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Days Inn & Suites Hotel

220 S Interstate Dr, Sikeston, MO 63801

Contact for pricing

40,148 sqft 10.50 AC lot

Hospitality property with renovated interiors, event facilities, dining areas, a pool, and fitness room.

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Interstate-Access Commercial Land

3,5,7,9 Charleston Plaza, Charleston, MO 63834

$950,000

11.04 AC lot

Commercial land offering substantial acreage near Interstate 57 in Charleston, Missouri.

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Commercial Land with Asphalt Surface

224 South Interstate Drive, Sikeston, MO 63801

$199,000

87,120 sqft

Commercial zoning and an asphalt surface support future build-to-suit development.

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Office Building with Open Floor Space

2380 S. Main, Charleston, MO 63834

$84,000

1,452 sqft 0.73 AC lot

Commercially zoned property with central heating and cooling, two private offices, and additional rear work area.

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Off-Market Properties in East Prairie, MO

Consider similar Off-Market properties in East Prairie, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.