Sign Up Successful!
You now have access to more from Realmo!
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    De Soto, MO Commercial Real Estate for Sale

    Notify Me
    List
    Map
    Established Tire Business with Real Estate
    $115,000
    2,541 SF

    Established Tire Business with Real Estate

    112 W Kelley St, De Soto, MO 63020

    Operating used tire business with real estate in De Soto.

    • Established used tire business with real estate included, offering immediate business opportunity.
    • Commercial building featuring a customer area, office, bathroom, and convenient 4‑bay lean‑to.
    • Includes business equipment, inventory, and tire stock (quantity subject to change).
    • Potential for continued business growth and real estate value appreciation.
    • 1920 two‑story house with rehab potential for rental income or business use.
    Updated: Jan 11
    View details
    De Soto Church Building on 5+ Acres
    $399,900
    3,739 SF

    De Soto Church Building on 5+ Acres

    4041 Maple Downs Ct, De Soto, MO 63020

    Church building with spacious sanctuary and high-visibility location.

    • Spacious 5+/- acre property with high visibility location.
    • Large sanctuary with high ceilings and ample natural light, seating for approximately 140.
    • Newer construction (built in 2007) and in move‑in ready condition.
    • Large paved parking area with 40+ spaces and room for expansion.
    • Zoned HVAC systems for efficient climate control.
    Updated: Aug 28, 2025
    View details
    De Soto Retail Business Opportunity
    $850,000
    15,500 SF

    De Soto Retail Business Opportunity

    Own a business and a piece of history!

    400 S Main St, De Soto, MO 63020
    View details
    De Soto Investment Property Portfolio
    $680,000
    0.34 Acres

    De Soto Investment Property Portfolio

    Eight-unit portfolio in growing rental market near schools and highways.

    206 Kronos Dr, De Soto, MO 63020
    View details
    Commercial Land with Pole Barn
    $319,900
    3.50 Acres

    Commercial Land with Pole Barn

    3.5 acres of commercial land with automotive shop potential.

    13659 Klondike Dr, De Soto, MO 63020
    View details
    Based on your search, we've compiled 366 Potential Opportunities for your consideration. Besides 5 Active listings in De Soto, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 357 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Spacious Multi-Home Property on 5.4 Acres
    $425,000
    2,588 SF

    Spacious Multi-Home Property on 5.4 Acres

    Three homes on 5.4 acres, ideal for homesteading or rental income.

    1818 Hunter Rd, Festus, MO 63028
    View details
    Festus Multi-Tenant Property For Sale
    Pending
    $1,150,000
    3,420 SF

    Festus Multi-Tenant Property For Sale

    Multi-tenant property on 12 acres near Hwy 67.

    3041 Meyer Rd, Festus, MO 63028
    View details
    Hillsboro Retail Center Investment
    Pending
    $950,000
    19,936 SF

    Hillsboro Retail Center Investment

    Fully occupied retail center in Hillsboro, MO with 10% cap rate.

    10814 Business 21, Hillsboro, MO 63050
    View details
    Hillsboro Land with Modern Home
    $325,000
    10.15 Acres

    Hillsboro Land with Modern Home

    Secluded 10-acre property with a 2021-built manufactured home.

    150 Dubuque Ln, Hillsboro, MO 63050
    View details

    Explore Off-Market Properties in De Soto, MO

    Consider similar Off-Market properties in De Soto, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    6020 Nmi Dr

    6020 Nmi Dr

    MINI-WAREHOUSE, STORAGE • 20,754 SF
    Value Estimation
    $465,000
    6020 Nmi Dr, De Soto, MO 63020-3587
    View details
    116th Easton St

    116th Easton St

    DISTRIBUTION WAREHOUSE • 12,550 SF
    Value Estimation
    $290,000
    116th Easton St, De Soto, MO 63020-1706
    View details
    309 Main St

    309 Main St

    MINI-WAREHOUSE, STORAGE • 7,030 SF
    Value Estimation
    $280,000
    309 Main St, De Soto, MO 63020-2141
    View details
    510 Main St

    510 Main St

    DISTRIBUTION WAREHOUSE • 0.21 Acres
    Value Estimation
    $265,000
    510 Main St, De Soto, MO 63020-2204
    View details
    De Soto, MO 63020

    De Soto, MO 63020

    MINI-WAREHOUSE, STORAGE • 12,300 SF
    Value Estimation
    $340,000
    De Soto, MO 63020
    View details
    De Soto, MO 63020

    De Soto, MO 63020

    DISTRIBUTION WAREHOUSE • 0.36 Acres
    Value Estimation
    $260,000
    De Soto, MO 63020
    View details
    13239 State Rte 21

    13239 State Rte 21

    MANUFACTURING (LIGHT) • 3,500 SF
    Value Estimation
    $300,000
    13239 State Rte 21, De Soto, MO 63020-4323
    View details
    5390 State Rd P P

    5390 State Rd P P

    DISTRIBUTION WAREHOUSE • 0.29 Acres
    Value Estimation
    $265,000
    5390 State Rd P P, De Soto, MO 63020
    View details
    300 Main St

    300 Main St

    DISTRIBUTION WAREHOUSE • 0.21 Acres
    Value Estimation
    $265,000
    300 Main St, De Soto, MO 63020
    View details
    517 Main St

    517 Main St

    DISTRIBUTION WAREHOUSE • 0.32 Acres
    Value Estimation
    $260,000
    517 Main St, De Soto, MO 63020-2227
    View details
    4290 Fountain City Rd

    4290 Fountain City Rd

    DISTRIBUTION WAREHOUSE • 1,920 SF
    Value Estimation
    $255,000
    4290 Fountain City Rd, De Soto, MO 63020
    View details
    106 Stone St

    106 Stone St

    DISTRIBUTION WAREHOUSE • 1,120 SF
    Value Estimation
    $240,000
    106 Stone St, De Soto, MO 63020-2403
    View details
    De Soto, MO 63020

    De Soto, MO 63020

    MANUFACTURING (LIGHT) • 0.04 Acres
    Value Estimation
    $300,000
    De Soto, MO 63020
    View details
    116 Easton St

    116 Easton St

    DISTRIBUTION WAREHOUSE • 4,450 SF
    Value Estimation
    $265,000
    116 Easton St, De Soto, MO 63020-1706
    View details
    918 Main St

    918 Main St

    LUMBERYARD, BUILDING MATERIALS • 0.55 Acres
    Value Estimation
    $295,000
    918 Main St, De Soto, MO 63020-2328
    View details
    12521 State Rte 21

    12521 State Rte 21

    MINI-WAREHOUSE, STORAGE • 832 SF
    Value Estimation
    $380,000
    12521 State Rte 21, De Soto, MO 63020-3316
    View details
    4025 Fountain City Rd

    4025 Fountain City Rd

    DISTRIBUTION WAREHOUSE • 5.33 Acres
    Value Estimation
    $275,000
    4025 Fountain City Rd, De Soto, MO 63020-3430
    View details
    12507 Old County Rd

    12507 Old County Rd

    DISTRIBUTION WAREHOUSE • 1.78 Acres
    Value Estimation
    $265,000
    12507 Old County Rd, De Soto, MO 63020-3190
    View details
    1815 Rock Rd

    1815 Rock Rd

    MINI-WAREHOUSE, STORAGE • 14,812 SF
    Value Estimation
    $345,000
    1815 Rock Rd, De Soto, MO 63020
    View details

    De Soto, MO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 329 commercial real estate investment opportunities in De Soto, MO on our commercial real estate marketplace. The current inventory includes 57,246,831 square feet of properties with an estimated value of $67,978,200.

    Estimated prices for commercial real estate in De Soto, MO begin at $55,000, with an average of $325,254 and extend to $950,000.

    In De Soto, MO, current investment values show:

    • Retail properties positioned at $343,410
    • Individual retail properties measuring $404,390
    • Multifamily properties assessed at $314,242
    • Residential income properties calculated at $314,242
    List
    Map

    Browse Commercial real estate for Sale Near De Soto, MO

    Popular Searches in De Soto, MO

    Most Searched ZIP Codes in De Soto, MO

    • 63020
    • 63087

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.