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    Florence, CO Commercial Real Estate for Sale

    35 results
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    Historic Building in Florence's Golden Block
    $349,500
    0.08 Acres

    Historic Building in Florence's Golden Block

    111 W Main St, Florence, CO 81226

    Refurbished commercial building in Florence's thriving downtown district.

    • Prime "Golden Block" location in Florence's Antique Capital of America with high foot traffic and excellent visibility.
    • Optional turnkey business: existing successful retail business available for purchase.
    • Refurbished historic building featuring exposed brick walls and updated flooring.
    • Flexible zoning suitable for retail, gallery, boutique, or other commercial ventures.
    • Practical amenities including a private garage, additional storage, rear staff parking, and a private restroom with utility sink.
    Updated: Mar 13
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    Historic Building in Florence's Golden Block
    $399,400
    0.08 Acres

    Historic Building in Florence's Golden Block

    111 W Main St, Florence, CO 81226

    Turnkey business opportunity in Florence's thriving downtown retail area.

    • Prime location in Florence's "Golden Block," the city's most coveted retail area.
    • Turnkey retail business opportunity, including inventory, fixtures, branding, and systems.
    • Historic building with exposed brick and updated flooring.
    • Flexible zoning allows for various commercial uses.
    • Private garage and additional storage space.
    Updated: Jan 10
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    Mixed-Use Investment in Historic Downtown
    $675,000
    0.08 Acres

    Mixed-Use Investment in Historic Downtown

    Live-work investment opportunity in Florence's Historic Downtown on Main Street.

    122 W Main St, Florence, CO 81226
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    Historic Downtown Florence Live-Work Space
    $675,000
    0.08 Acres

    Historic Downtown Florence Live-Work Space

    Live-work investment opportunity in historic downtown Florence, Colorado.

    122 W Main St, Florence, CO 81226
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    Mixed-Use Building in Florence, CO
    $300,000

    Mixed-Use Building in Florence, CO

    Classic mixed-use building with remodeling potential on Main Street.

    108 W Main St, Florence, CO 81226
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    Mixed-Use Property on Main Street
    $550,000
    15,519 SF

    Mixed-Use Property on Main Street

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 Main St, Florence, CO 81226
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    Main Street Mixed-Use Opportunity
    $550,000
    0.22 Acres

    Main Street Mixed-Use Opportunity

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 E Main St, Florence, CO 81226
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    Historic Mixed-Use Building with Loft
    $480,000
    2,850 SF

    Historic Mixed-Use Building with Loft

    Main Street investment opportunity with business spaces and luxury loft.

    119 Main St, Florence, CO 81226
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    Historic Mixed-Use Building on Main
    $450,000
    0.07 Acres

    Historic Mixed-Use Building on Main

    Charming mixed-use building with retail and residential units.

    100 E Main St, Florence, CO 81226
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    Historic Mixed-Use Building on Main
    $450,000
    0.07 Acres

    Historic Mixed-Use Building on Main

    Charming historic mixed-use building in Florence, Colorado.

    100 E Main St, Florence, CO 81226
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    Mixed-Use Building in Florence, CO
    $300,000
    0.17 Acres

    Mixed-Use Building in Florence, CO

    Classic mixed-use building with remodeling potential on Main Street.

    108 W Main St, Florence, CO 81226
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    Historic Downtown Florence Mixed-Use Building
    $480,000
    0.08 Acres

    Historic Downtown Florence Mixed-Use Building

    Mixed-use building with business spaces and luxury loft in Florence.

    119 W Main St, Florence, CO 81226
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    Commercial Land with Income Streams
    $285,000
    4.70 Acres

    Commercial Land with Income Streams

    4.7 acres with U-Haul dealership and propane refill operation.

    280 Moore Dr, Florence, CO 81226
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    Florence Land with Water Share
    $112,500
    3.78 Acres

    Florence Land with Water Share

    3.78 acres with water rights near Arkansas River.

    County Road 119, Florence, CO 81226
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    Versatile Industrial Property in Florence, CO
    $242,000
    4.63 Acres

    Versatile Industrial Property in Florence, CO

    4.63-acre industrial property equipped for commercial and contractor uses.

    120 E Cir Pl, Florence, CO 81226
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    Land Near Arkansas River
    $64,900
    3.17 Acres

    Land Near Arkansas River

    3+ acre lot near Arkansas River, Florence, Colorado.

    County Road 119, Florence, CO 81226
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    Historic Mixed-Use Property in Florence
    $480,000
    2,850 SF

    Historic Mixed-Use Property in Florence

    Mixed-use property with business spaces and luxury loft in Florence.

    119 W Main St, Florence, CO 81226
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    Land Near Arkansas River
    $125,000
    5.66 Acres

    Land Near Arkansas River

    5+ acre lot near Arkansas River, Florence, Colorado.

    County Road 119, Florence, CO 81226
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    Highway-Frontage Land Ready For Development
    $1,200,000
    26.76 Acres

    Highway-Frontage Land Ready For Development

    26+ acres of prime land with highway frontage and utilities.

    00 Shoop, Florence, CO 81226
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    Agricultural Land in Rainbow Park
    $112,500
    3.78 Acres

    Agricultural Land in Rainbow Park

    3.78 acres with agricultural water near Arkansas River.

    County Road 119, Florence, CO 81226
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    Main Street Mixed-Use Opportunity
    $550,000
    13,519 SF

    Main Street Mixed-Use Opportunity

    Mixed-use property with restaurant, retail, and apartment potential.

    102-106 Main St, Florence, CO 81226
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    Prime Highway Frontage Land
    $1,200,000
    26.76 Acres

    Prime Highway Frontage Land

    26+ acres with stoplight access and water infrastructure.

    Shoop Dr, Florence, CO 81226
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    2.89 Acre Lot in Florence
    $150,000
    2.89 Acres

    2.89 Acre Lot in Florence

    2.89 acre lot with country feel near Florence, Colorado.

    County Road 119, Florence, CO 81226
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    20 Acres with Mountain Views
    $99,999
    20.00 Acres

    20 Acres with Mountain Views

    20 acres of land with mountain views near Florence.

    709 County Road 108, Florence, CO 81226
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    Florence, CO Commercial Real Estate Investment Opportunities Market Analysis

    Explore 37 commercial real estate for sale in Florence, CO, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 4,698,294 square feet of properties for sale, with an estimated market value of $12,300,699.

    Sale prices for business properties in Florence, CO start at $64,900, averaging $439,310, and reaching up to $1,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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