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    Downtown San Francisco, CA Commercial Real Estate for Sale

    12 results
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    Commercial Asset in Lower Nob Hill
    $2,795,000
    3,795 SF

    Commercial Asset in Lower Nob Hill

    729 Bush Street, San Francisco, CA 94108

    Two-story commercial building with redevelopment potential near Union Square.

    • Prime location in San Francisco's Lower Nob Hill/Downtown, near Union Square and the Financial District, offering high foot traffic and visibility.
    • Flexible RC‑4 zoning allows for a wide range of commercial uses.
    • Significant redevelopment potential, including vertical expansion and modern medical build‑outs.
    • Large 3,781‑sq ft lot, a rare find in this area.
    • Excellent transportation access via BART, cable cars, and MUNI.
    Updated: Sep 21, 2025
    View details
    San Francisco Mixed-Use Investment Property
    $1,650,000
    0.02 Acres

    San Francisco Mixed-Use Investment Property

    550-552 Grant Avenue, San Francisco, CA 94108

    Mixed-use property in San Francisco's Chinatown with retail and residential.

    • Prime location in San Francisco's Chinatown with high foot traffic.
    • Mixed‑use property suitable for investors or owner‑users.
    • Large retail storefront on Grant Avenue with mezzanine floor, waterbar, basement, office, and restroom.
    • Updated residential units: a 2‑bedroom/1‑bathroom unit and a 3‑bedroom/1.5‑bath unit.
    • Residential units face the park.
    Updated: Oct 15, 2025
    View details
    Former Tuxedo Building on Kearny
    $2,999,999
    4,727 SF

    Former Tuxedo Building on Kearny

    Three-story building with a basement in a vibrant area.

    227 Kearny Street, San Francisco, CA 94108
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    South of Market Full Building
    $12,000,000
    12,000 SF

    South of Market Full Building

    12,000 SF building in the heart of South of Market.

    667 Howard Street, San Francisco, CA 94105
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    Downtown San Francisco Commercial Duplex
    $1,295,000
    2,192 SF

    Downtown San Francisco Commercial Duplex

    Inspiring space ideal for creative, retail, or professional use.

    767 Bush Street, San Francisco, CA 94108
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    Versatile Commercial Building in Nob Hill
    $2,795,000
    5,072 SF

    Versatile Commercial Building in Nob Hill

    Two-story commercial building with redevelopment potential in a prime location.

    729 Bush Street, San Francisco, CA 94108
    View details
    Mixed-Use Building in Prime Location
    $5,200,000
    13,950 SF

    Mixed-Use Building in Prime Location

    Mixed-use building with retail, office, and residential units.

    450 Grant Avenue, San Francisco, CA 94108
    View details
    Renovated Mixed-Use Property For Sale
    $2,999,000
    5,500 SF

    Renovated Mixed-Use Property For Sale

    Mixed-use property with residential and office units, renovated in 2023.

    883 Sacramento Street, San Francisco, CA 94108
    View details
    South Beach Commercial Condo
    $988,000
    1,469 SF

    South Beach Commercial Condo

    1,469 SF commercial condo in San Francisco's South Beach.

    400 Beale Street #103, San Francisco, CA 94105
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    Prime Chinatown Mixed-Use Investment
    $1,650,000
    0.02 Acres

    Prime Chinatown Mixed-Use Investment

    Mixed-use property in San Francisco's Chinatown with retail and residential.

    550 Grant Avenue, San Francisco, CA 94108
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    Mixed-Use Trophy Corner Building
    $8,500,000
    20,845 SF

    Mixed-Use Trophy Corner Building

    Mixed-use building with hotel and retail in Union Square.

    507 Bush Street, San Francisco, CA 94108
    View details
    San Francisco Office Building For Sale
    $5,800,000
    19,212 SF

    San Francisco Office Building For Sale

    Office building with 19,212 square feet available for sale.

    924 Sansome St, San Francisco, CA 94111
    View details
    Based on your search, we've compiled 2045 Potential Opportunities for your consideration. Besides 12 Active listings in Downtown San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2025 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Sausalito Medical and Wellness Campus
    $2,849,999
    4,266 SF

    Sausalito Medical and Wellness Campus

    Two-building medical campus with garden and gated parking.

    111 2nd, Sausalito, CA 94965
    View details
    Sausalito Waterfront Office/Retail Opportunity
    $5,995,000
    8,400 SF

    Sausalito Waterfront Office/Retail Opportunity

    Prime Sausalito waterfront property with office, retail, and parking.

    599 Bridgeway, Sausalito, CA 94965
    View details
    Vacant Land with High Visibility
    $8,000,000

    Vacant Land with High Visibility

    19,300 SF vacant land with mixed-use zoning.

    2321 Geneva Avenue, Daly City, CA 94014
    View details
    Daly City Industrial Space
    $4,995,000
    14,200 SF

    Daly City Industrial Space

    14,200 SqFt industrial property available in Daly City, CA.

    3275 Geneva Ave, Daly City, CA 94014
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Chinatown Vacant Lot For Sale
    $260,000
    1,245 SF

    Chinatown Vacant Lot For Sale

    Rare vacant lot in Chinatown's epicenter with parking potential.

    940 Washington St, San Francisco, CA
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    San Francisco Development Opportunity
    $2,500,000

    San Francisco Development Opportunity

    Prime North Beach location with development potential and existing income.

    65 Fresno St, San Francisco, CA 94133
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    SOMA Land with Development Potential
    $1,250,000
    3,746 SF

    SOMA Land with Development Potential

    Centrally located land suitable for storage, light industrial, development.

    173-175 Shipley St, San Francisco, CA
    View details
    Vacant Land in SoMa
    $1,195,000
    0.09 Acres

    Vacant Land in SoMa

    Vacant land with approved site permit in vibrant location.

    265 Shipley Street, San Francisco, CA 94107
    View details

    Explore Off-Market Properties in Downtown San Francisco, CA

    Consider similar Off-Market properties in Downtown San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    52 2nd St, Unit 54

    52 2nd St, Unit 54

    RETAIL STORES (PERSONAL SERVICES) • 5,656 SF
    Value Estimation
    $1,720,000
    52 2nd St, San Francisco, CA 94105-3427
    View details
    201 Folsom St, Unit 19G

    201 Folsom St, Unit 19G

    APARTMENT HOUSE (5+ UNITS) • 1,401 SF
    Value Estimation
    $1,850,000
    201 Folsom St, San Francisco, CA 94105-5075
    View details
    1075 California St

    1075 California St

    HOTEL • 143,673 SF
    Value Estimation
    $10,465,000
    1075 California St, San Francisco, CA 94108-2251
    View details
    732 Washington St

    732 Washington St

    PARKING LOT • 0.11 Acres
    Value Estimation by Request
    732 Washington St, San Francisco, CA 94108-1305
    View details
    1045 Sansome St

    1045 Sansome St

    OFFICE BUILDING • 89,010 SF
    Value Estimation
    $25,580,000
    1045 Sansome St, San Francisco, CA 94111-1311
    View details
    130 Sutter St, Unit 150

    130 Sutter St, Unit 150

    RETAIL STORES (PERSONAL SERVICES) • 108,432 SF
    Value Estimation
    $3,855,000
    130 Sutter St, San Francisco, CA 94104-4003
    View details
    1225 Clay St

    1225 Clay St

    APARTMENT HOUSE (5+ UNITS) • 8,418 SF
    Value Estimation
    $2,285,000
    1225 Clay St, San Francisco, CA 94108-1407
    View details
    30 Battery St

    30 Battery St

    PARKING GARAGE, PARKING STRUCTURE • 51,233 SF
    Value Estimation
    $2,435,000
    30 Battery St, San Francisco, CA 94111-5502
    View details
    1 Frnt St

    1 Frnt St

    OFFICE BUILDING • 605,459 SF
    Value Estimation
    $3,015,000
    1 Frnt St, San Francisco, CA 94111-5325
    View details
    318 Main St, Unit 4E

    318 Main St, Unit 4E

    APARTMENT HOUSE (5+ UNITS) • 1,098 SF
    Value Estimation by Request
    318 Main St, San Francisco, CA 94105-2182
    View details
    1225 Taylor St

    1225 Taylor St

    APARTMENT HOUSE (5+ UNITS) • 17,555 SF
    Value Estimation
    $7,615,000
    1225 Taylor St, San Francisco, CA 94108-1464
    View details
    134 Maiden Ln

    134 Maiden Ln

    RETAIL STORES (PERSONAL SERVICES) • 3,985 SF
    Value Estimation
    $1,595,000
    134 Maiden Ln, San Francisco, CA 94108-5302
    View details

    Downtown San Francisco, CA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2037 commercial real estate for sale in Downtown San Francisco, CA, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 9,812,391 square feet of properties for sale, with an estimated market value of $71,814,400.

    Sale prices for business properties in Downtown San Francisco, CA start at $599,000, averaging $3,122,365, and reaching up to $18,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Popular Searches in San Francisco, CA

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    Most Searched ZIP Codes in San Francisco, CA

    • 94108
    • 94105
    • 94111

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