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    Downtown San Francisco, CA Commercial Real Estate for Sale

    20 results
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    Commercial Asset in Lower Nob Hill
    $2,795,000
    3,795 SF

    Commercial Asset in Lower Nob Hill

    729 Bush St, San Francisco, CA 94108

    Two-story commercial building with redevelopment potential near Union Square.

    • Prime location in San Francisco's Lower Nob Hill/Downtown, near Union Square and the Financial District, offering high foot traffic and visibility.
    • Flexible RC‑4 zoning allows for a wide range of commercial uses.
    • Significant redevelopment potential, including vertical expansion and modern medical build‑outs.
    • Large 3,781‑sq ft lot, a rare find in this area.
    • Excellent transportation access via BART, cable cars, and MUNI.
    Updated: Dec 30, 2025
    View details
    Financial District Restaurant
    $3,750,000
    5,500 SF

    Financial District Restaurant

    525 Commercial St, San Francisco, CA 94111

    Turn-key restaurant, prime location.

    • $3,750,000 asking price for this owner‑user restaurant opportunity.
    • 5,500 square foot, three‑story free‑standing restaurant building in San Francisco's Financial District.
    • Features two full kitchens, ample seating across multiple levels, and potential for outdoor seating.
    • Located on Commercial Street, benefiting from high pedestrian traffic and proximity to major office towers.
    • Zoned C‑3‑O, with potential for future expansion including a rooftop patio.
    Updated: Dec 11, 2024
    View details
    Clintonville Medical Office Building
    $6,800,000
    19,212 SF

    Clintonville Medical Office Building

    Prime Clintonville location, 1860 sq ft.

    924 Sansome St, San Francisco, CA 94111
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    Historic Office Building in North Waterfront
    Contact for pricing
    44,976 SF

    Historic Office Building in North Waterfront

    44,976 SF historic office building in San Francisco's North Waterfront.

    55 Union St, San Francisco, CA 94111
    View details
    South of Market Full Building
    $12,000,000
    12,000 SF

    South of Market Full Building

    12,000 SF building in the heart of South of Market.

    667 Howard St, San Francisco, CA 94105
    View details
    Grant Avenue Retail Opportunity
    $2,900,000
    9,160 SF

    Grant Avenue Retail Opportunity

    Four-unit commercial property with former restaurant space for sale.

    522-528 Grant Ave, San Francisco, CA 94108
    View details
    Mission Critical Lab Facility
    Contact for pricing
    49,560 SF

    Mission Critical Lab Facility

    49,560 SF lab facility 100% leased to Google.

    40 Jessie St, San Francisco, CA 94105
    View details
    Renovated Office Building For Sale
    $7,500,000
    12,500 SF

    Renovated Office Building For Sale

    Newly renovated office building with creative spaces and conference rooms.

    632 Commercial St, San Francisco, CA 94111
    View details
    Commercial Condo in Vibrant Community
    $599,000
    1,875 SF

    Commercial Condo in Vibrant Community

    1,875 SF commercial condo, 1,320 SF available for occupancy.

    929 Clay St, San Francisco, CA 94108
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    Union Square Retail Opportunity
    Contact for pricing
    39,913 SF

    Union Square Retail Opportunity

    Prime retail space in the heart of Union Square.

    212 Stockton St, San Francisco, CA 94108
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    Prime Retail Space Near Union
    Contact for pricing
    7,079 SF

    Prime Retail Space Near Union

    Retail space with high visibility near Union Square and Chinatown.

    311 Grant Ave, San Francisco, CA 94108
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    Union Square Mixed-Use Building
    Contact for pricing
    18,818 SF

    Union Square Mixed-Use Building

    Mixed-use building in Union Square with retail and office space.

    45-50 Maiden Ln, San Francisco, CA 94108
    View details
    Prime Location Retail Building
    $4,500,000
    12,222 SF

    Prime Location Retail Building

    Standalone building in prime location with convenient access to transit.

    435-443 Broadway St, San Francisco, CA 94111
    View details
    Chinatown Commercial Condo Units
    $500,000
    6,678 SF

    Chinatown Commercial Condo Units

    Seven commercial condo units in high-traffic Chinatown location.

    950 Stockton St, San Francisco, CA 94108
    View details
    Mixed-Use Property in Financial District
    $8,000,000
    23,265 SF

    Mixed-Use Property in Financial District

    36-unit mixed-use property in San Francisco's Financial District/Chinatown.

    819-831 Sacramento St, San Francisco, CA 94108
    View details
    Mixed-Use Property in San Francisco
    $1,125,000
    3,468 SF

    Mixed-Use Property in San Francisco

    Mixed-use property with retail and residential units in San Francisco.

    732 Sacramento St, San Francisco, CA 94108
    View details
    Union Square Retail Investment Opportunity
    Contact for pricing
    11,500 SF

    Union Square Retail Investment Opportunity

    Prime retail property in Union Square's luxury zone.

    152 Geary St, San Francisco, CA 94108
    View details
    Union Square Three-Story Building
    $3,500,000
    5,175 SF

    Union Square Three-Story Building

    Three-story building in Union Square neighborhood of San Francisco.

    124-126 Sutter St, San Francisco, CA 94104
    View details
    Mixed-Use Property in Telegraph Hill
    $4,300,000
    8,829 SF

    Mixed-Use Property in Telegraph Hill

    45-unit mixed-use property with retail and SRO units.

    371-377 Broadway St, San Francisco, CA 94111
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in Downtown San Francisco, CA, we suggest to view alternatives - similar 28016 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Downtown San Francisco, CA

    Consider similar Off-Market properties in Downtown San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    58 Maiden Ln

    58 Maiden Ln

    Office space • 39,000 SF
    Value Estimation by Request
    58 Maiden Ln, San Francisco, CA 94108
    View details
    80 Grant Ave

    80 Grant Ave

    Retail properties • 4,000 SF
    Value Estimation by Request
    80 Grant Ave, San Francisco, CA 94108
    View details
    1300 Battery St

    1300 Battery St

    Restaurants • 3,997 SF
    Value Estimation by Request
    1300 Battery St, San Francisco, CA 94111
    View details
    212 Sutter St

    212 Sutter St

    Office Properties & Spaces • 6,000 SF
    Value Estimation by Request
    212 Sutter St, San Francisco, CA 94108
    View details

    Downtown San Francisco, CA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 2014 commercial real estate investment opportunities in Downtown San Francisco, CA with 20 listings featured on our commercial real estate marketplace. The current inventory includes 497,790,368 square feet of properties with an estimated value of $13,507,901,400.

    Estimated prices for commercial real estate in Downtown San Francisco, CA begin at $50,000, with an average of $1,298,711 and extend to $29,710,000.

    In Downtown San Francisco, CA, current investment values show:

    • Multifamily properties positioned at $1,329,997
    • Residential income properties measuring $1,329,997
    • Apartment buildings assessed at $1,318,920
    • Other apartment buildings calculated at $1,658,757
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    Popular Searches in San Francisco, CA

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    Most Searched ZIP Codes in San Francisco, CA

    • 94103
    • 94110
    • 94109
    • 94124
    • 94112
    • 94107
    • 94102
    • 94133
    • 94108
    • 94118
    • 94122
    • 94131

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